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1248978 
Journal Article 
Association of arsenic levels in soil and water with urinary arsenic concentration of residents in the vicinity of closed metal mines 
Cho, Y; Seo, S; Choi, SH; Lee, S; Kim, K; Kim, HJ; Choi, JW 
In Press 
International Journal of Hygiene and Environmental Health
ISSN: 1438-4639
EISSN: 1618-131X 
English 
WOS:000317873700005 
Arsenic (As) pollution in the surroundings of metal mines has been observed, and may induce serious health problems, in particular cancer. Health hazard attributed to As in contaminated soil and water in the vicinity of closed or abandoned metal mines may be high. Little is known about how environmental exposure to As has affected the health of resident near closed metal mines. The objectives of this study were to compare the urinary level of As for those living near closed metal mines (the exposed group) with that of non-exposed group; and to investigate the correlation between As levels in soil (Soil(As)) and water (Water(As)) and the urinary levels (Urine(As)) of residents in the exposed group. Data for Soil(As) and Water(As) were obtained from the national environmental survey performed between 2003 and 2005 by the Ministry of Environment in Korea. To measure Urine(As), 2674 and 237 subjects were selected from 67 closed metal mines (exposed areas) and two rural areas (non-exposed areas), respectively. Five milliliters of urine samples were taken, and graphite furnace atomic absorption spectrometry was used to analyze Urine(As). Of all the exposed areas, high Soil(As) and Water(As) areas that exceed the Korean standards of As in soil (6mg/kg-soil) and stream or groundwater (0.05mg/l-water) were classified to evaluate the health risks in high polluted areas. Also, high Urine(As) group was defined as 20μg/g creatinine or more. Student's t-test was performed to compare the Urine(As) level between the exposed and non-exposed groups. The odds ratio (OR) was calculated by a logistic analysis to evaluate the risk for high Urine(As) level from high Soil(As) and Water(As) areas. The mean of urinary As were 8.90±8.34μg/g-creatinine for the exposed group and 7.68±4.98μg/g creatinine for the non-exposed group, respectively; and the significant difference of urinary As level was observed between both groups (p<0.05). Moreover, the means for urinary As of people in areas with high As level in soil and water were significantly higher than that for the control areas (p<0.001), and these differences were more pronounced for the As level in water. The odds of subjects with high Urine(As) were positively and significantly associated with living in the areas with high As level in soil (OR=1.62; 95% C.I.=1.13-2.31). These associations were much stronger for the areas with high Water(As) (OR=3.79; 95% C.I.=2.32-6.19). These results indicate that the high level of As in environment may increase the risk of having high urinary As level of people in the exposed areas. 
Closed metal mines; Arsenic contamination; Arsenic exposure; Urinary arsenic 
IRIS
• Arsenic
     Initial Lit Search
          PubMed
     Lit Search May 2013-June 2013
          PubMed
          WOS
          Considered New
     Lit Search June 2013-July 2013
          PubMed
          Considered New
     Lit Search Aug 2013-Sept 2013
          ToxNet
          Considered New
     Lit Search Sept 2013-Oct 2013
          ToxNet
          Excluded
               Toxnet Duplicates
     Lit Search Oct 2013-Nov 2013
          ToxNet
          Excluded
               Toxnet Duplicates
     Lit Search Nov 2013-Dec 2013
          ToxNet
          Excluded
               Toxnet Duplicates
     Lit Search Dec 2013-Jan 2014
          ToxNet
          Excluded
               Toxnet Duplicates
     Supplementary Lit Search
          PubMed
          WOS
          ToxNet
          Considered
     Considered
     Cluster Filter
     Other Studies
          Exposure Assessment
 
Adolescent 
Adult 
Aged 
Aged, 80 and over 
Arsenic 
Child 
Environmental Monitoring 
Female 
Humans 
Male 
Metals, Heavy 
Middle Aged 
Mining 
Republic of Korea 
Soil Pollutants 
Water Pollutants, Chemical 
Young Adult 
 

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