National human exposure assessment survey (NHEXAS): Distributions and associations of lead, arsenic, and volatile organic compounds in EPA Region 5 | Health & Environmental Research Online (HERO)

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National human exposure assessment survey (NHEXAS): Distributions and associations of lead, arsenic, and volatile organic compounds in EPA Region 5

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HERO ID

014003

Reference Type

Journal Article

Title

National human exposure assessment survey (NHEXAS): Distributions and associations of lead, arsenic, and volatile organic compounds in EPA Region 5

Author(s)

Clayton, CA; Pellizzari, ED; Whitmore, RW; Perritt RL Quackenboss, JJ

Year

1999

Journal

Journal of Exposure Science and Environmental Epidemiology
ISSN: 1559-0631
EISSN: 1559-064X

Volume

Issue

Page Numbers

381-392

Language

English

PMID

10554141

DOI

10.1038/sj.jea.7500055

Abstract

The National Human Exposure Assessment Survey (NHEXAS) Phase I field study conducted in EPA Region 5 provides extensive exposure data on approximately 250 study participants selected via probability sampling. Associated environmental media and biomarker (blood, urine) concentration data were also obtained to aid in the understanding of relationships of the exposures to both contaminant sources and doses. Distributional parameters for arsenic (As), lead (Pb), and four volatile organic compounds (VOCs)--benzene, chloroform, tetrachloroethylene, and trichloroethylene--were estimated for each of the relevant media using weighted data analysis techniques. Inter-media associations were investigated through correlation analysis, and longitudinal correlations and models were used to investigate longitudinal patterns. Solid food appeared to be a major contributor to urine As levels, while Pb levels in household (HH) dust, personal air, and beverages all were significantly associated with blood Pb levels. Relatively high(>0.50) longitudinal correlations were observed for tap water Pb and As, as compared to only moderate longitudinal correlations for the personal air VOCs.

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