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PFUnA (2058-94-8)


250 References Were Found:

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Temporal and spatial trends of perfluorinated compounds in ringed seal (Phoca hispida) from Greenland

Authors: Bossi, R; Riget, FF; Dietz, R (2005) Environmental Science and Technology 39:7416-7422. HERO ID: 1332755

[Less] Perfluorinated compounds (PFCs), such as perfluorooctane sulfonate (PFOS) and related compounds, have . . . [More] Perfluorinated compounds (PFCs), such as perfluorooctane sulfonate (PFOS) and related compounds, have been identified as global pollutants and have shown their bioaccumulation into higher trophic levels in the food chain. PFCs have been found in remote areas far from sources, such as the Arctic. In this study spatial and temporal trends in the concentrations of selected PFCs were measured using archived liver samples of ringed seal (Phoca hispida) from East and West Greenland. The samples were collected in four different years at each location, between 1986 and 2003 in East Greenland and between 1982 and 2003 in West Greenland. PFOS was the major contributor to the burden of PFCs in samples, followed by perfluoroundecanoic acid (PFUnA). Perfluorononanoic acid (PFNA) and perfluorodecanoic acid (PFDA) were also detected in most samples. Perfluorohexane sulfonate (PFHxS) and perfluorooctane sulfonamide (PFOSA) were only found sporadically. Perfluorooctanoic acid was not found in detectable concentrations in any sample. Regression analysis of logarithmic transformed PFOS, PFDA, and PFUnA median concentrations indicated a significant temporal trend with increasing concentrations at both locations. A spatial trend in PFOS concentrations (ANOVA, p < 0.0001) was observed between the two sampling locations, with significantly higher concentrations in seals from East Greenland.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Biochemical effect evaluation of perfluorooctane sulfonic acid-contaminated wood mice (Apodemus sylvaticus)

Authors: Hoff, PT; Scheirs, J; Van de Vijver, K; Van Dongen, W; Esmans, EL; Blust, R; De Coen, W (2004) Environmental Health Perspectives 112:681-686. HERO ID: 3860778

[Less] Wood mice (Apodemus sylvaticus) were captured at Blokkersdijk, a nature reserve in the immediate vicinity . . . [More] Wood mice (Apodemus sylvaticus) were captured at Blokkersdijk, a nature reserve in the immediate vicinity of a fluorochemical plant in Antwerp, Belgium, and at Galgenweel, 3 kilometers farther away. The liver perfluorooctane sulfonic acid (PFOS) concentrations in the Blokkersdijk mice were extremely high (0.47-178.55 micro g/g wet weight). Perfluorononanoic, perfluorodecanoic, perfluoroundecanoic, and perfluorododecanoic acids were found sporadically in the liver tissue of the Blokkersdijk mice. The liver PFOS concentrations at Galgenweel were significantly lower than those at Blokkersdijk (0.14-1.11 micro g/g wet weight). Further results suggest sex independence of the liver PFOS levels, increased levels of PFOS bioaccumulation in older mice, and maternal PFOS transfer to the young. Several liver end points were significantly elevated in the Blokkersdijk mice: liver weight, relative liver weight, peroxisomal beta-oxidation activity, microsomal lipid peroxidation level, and mitochondrial fraction protein content. For the mitochondrial fraction catalase activity, no significant difference between locations was found. The liver weight, relative liver weight, and liver microsomal lipid peroxidation level increased significantly with the liver PFOS concentration. No indications for PFOS-mediated effects on the serum triglyceride, cholesterol, or potassium levels were obtained. The liver PFOS concentration was negatively related to the serum alanine aminotransferase activity.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Isolating isomers of perfluorocarboxylates in polar bears (Ursus maritimus) from two geographical locations

Authors: De Silva, AO; Mabury, SA (2004) Environmental Science and Technology 38:6538-6545. HERO ID: 3858667

[Less] The source of involatile, anthropogenic perfluorocarboxylate anions (PFCAs) in biota from remote regions . . . [More] The source of involatile, anthropogenic perfluorocarboxylate anions (PFCAs) in biota from remote regions is of heightened interest due to the persistence, toxicity, and bioaccumulation of these materials. Large-scale production of fluorinated compounds is carried out primarily by one of two methods: electrochemical fluorination (ECF) and telomerization. Products of the two processes may be distinguished based on constitutional isomer pattern as ECF products are characteristically comprised of a variety of constitutional isomers. The objective of this research was to develop a method for identifying the constitutional isomer profile of PFCAs in environmental samples and to apply the method to polar bear livers from two different locations. Resolution of constitutional isomers of derivatized PFCAs (8-13 carbons) was accomplished via GC-MS. Seven isomers of an authentic ECF perfluorooctanoate (PFOA) standard were separated. The linear isomer comprised 78% of this standard. Isomer profiles of PFCAs in liver samples of 15 polar bears (Ursus maritimus) from the Canadian Arctic and eastern Greenland were determined by GC-MS. The PFOA isomer pattern in Greenland polar bear samples showed a variety of branched isomers while only the linear PFOA isomer was determined in Canadian samples. Samples of both locations had primarily (>99%) linear isomers of perfluorononanoate and perfluorotridecanoate. Branched isomers of perfluorodecanoate, perfluoroundecanoate, and perfluorododecanoate were determined in the polar bear samples. Unlike the PFOA isomer signature, only a single branched isomer peak on the chromatograms was observed for these longer chain PFCAs. The presence of branched isomers suggests some contribution from ECF sources. However, in comparison to the amount of branched isomers in the ECF PFOA standard, such minor percentages of branched PFCAs may suggest additional input from an exclusively linear isomer source.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Perfluorooctanesulfonate and related fluorochemicals in human blood from several countries

Authors: Kannan, K; Corsolini, S; Falandysz, J; Fillmann, G; Kumar, KS; Loganathan, BG; Mohd, MA; Olivero, J; Van Wouwe, N; Yang, JH; Aldoust, KM (2004) Environmental Science and Technology 38:4489-4495. HERO ID: 1290849

[Less] Perfluorooctanesulfonyl fluoride based compounds have been used in a wide variety of consumer products, . . . [More] Perfluorooctanesulfonyl fluoride based compounds have been used in a wide variety of consumer products, such as carpets, upholstery, and textiles. These compounds degrade to perfluorooctanesulfonate (PFOS), a persistent metabolite that accumulates in tissues of humans and wildlife. Previous studies have reported the occurrence of PFOS, perfluorohexanesulfonate (PFHxS), perfluorooctanoate (PFOA), and perfluorooctanesulfonamide (PFOSA) in human sera collected from the United States. In this study, concentrations of PFOS, PFHxS, PFOA, and PFOSA were measured in 473 human blood/serum/plasma samples collected from the United States, Colombia, Brazil, Belgium, Italy, Poland, India, Malaysia, and Korea. Among the four perfluorochemicals measured, PFOS was the predominant compound found in blood. Concentrations of PFOS were the highest in the samples collected from the United States and Poland (>30 ng/mL); moderate in Korea, Belgium, Malaysia, Brazil, Italy, and Colombia (3 to 29 ng/mL); and lowest in India (<3 ng/mL). PFOA was the next most abundant perfluorochemical in blood samples, although the frequency of occurrence of this compound was relatively low. No age- or gender-related differences in the concentrations of PFOS and PFOA were found in serum samples. The degree of association between the concentrations of four perfluorochemicals varied, depending on the origin of the samples. These results suggested the existence of sources with varying levels and compositions of perfluorochemicals, and differences in exposure patterns to these chemicals, in various countries. In addition to the four target fluorochemicals measured, qualitative analysis of selected blood samples showed the presence of other perfluorochemicals such as perfluorodecanesulfonate (PFDS), perfluoroheptanoic acid (PFHpA), perfluorononanoic acid (PFNA), perfluorodecanoic acid (PFDA), perfluorododecanoic acid (PFDoA), and perfluoroundecanoic acid (PFUnDA) in serum samples, at concentrations approximately 5- to 10-fold lower than the concentration of PFOS. Further studies should focus on identifying sources and pathways of human exposure to perfluorochemicals.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Time-resolved fluorescence quenching study of aqueous solutions of perfluorinated surfactants with the use of protiated luminophore and quencher

Authors: Szajdzinska-Pietek, E; Wolszczak, M (2000) Langmuir 16:1675-1680. HERO ID: 3749162

[Less] Application of fluorescence methods to study micellar solutions of perfluorinated surfactants is very . . . [More] Application of fluorescence methods to study micellar solutions of perfluorinated surfactants is very scarce because good probes and quenchers could not be found; polycyclic aromatic compounds, the most popular fluorescent probes, are difficult to solubilize into fluorinated surfactant micelles. We have found that the incompatibility of protiated probes with perfluorinated chains of surfactant host may be counterbalanced by positive electrostatic interactions. We present the use of a cationic derivative of pyrene,1-pyrenebutyltrimethylammonium bromide, as a luminophore and cationic quenchers, 1-trimethylammonium-2,2,6,6-tetramethyl-piperidine-1-oxyl iodide (nitroxide radical known as CAT1) and 1,1'-dimethyl-4,4'bipyridinium dichloride (methyl viologen), to examine aqueous solutions of two anionic fluorinated surfactants, ammonium perfluorooctanoate (APFO) and tetraethylammonium perfluorooctyl sulfonate (TEAPFOS). On the basis of the Infelta-Tachiya model, we have determined from time-resolved fluorescence quenching data the micellar aggregation numbers, the rate constants of intramicellar quenching, and the rate constants of the quencher exit from the aggregates. The results indicate formation of ellipsoidal micelles in APFO solution, with the aggregation numbers increasing versus surfactant concentration (from 33 at 0.06 M APFO to 109 at 0.5 M APFO), and threadlike micelles in TEAPFOS solution, which consist of interconnected spherical units each containing at least 52 surfactant molecules.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Micelle formation of lithium 1-perfluoroundecanoate

Authors: Moroi, Y; Take'uchi, M; Yoshida, N; Yamauchi, A (1998) Journal of Colloid and Interface Science 197:221-229. HERO ID: 3860725

[Less] Solution properties of lithium 1-perfluoroundecanoate have been studied by electroconductivity and membrane . . . [More] Solution properties of lithium 1-perfluoroundecanoate have been studied by electroconductivity and membrane potential measurements. The degree of counterion binding to micelles was not precisely determined by the Corrin-Harkins plots. The aggregation numbers and the degrees of counterion binding over the temperature range from 288.2 to 313.2 K have been evaluated by a new method that combined the above two measurements and the mass-action model. The thermodynamic parameters of micellization were determined from the temperature dependence of the parameters obtained. The surfactant with a long perfluoroalkyl chain showed micellization properties much different from the corresponding hydrocarbon surfactant in that the temperature dependence of the aggregation number, the degree of counterion binding, the enthalpy change of micellization, and the entropy change of micellization are much greater. (C) 1998 Academic Press.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Solubilization of n-Alkylbenzenes into Lithium 1-Perfluoroundecanoate Micelles

Authors: Take'uchi; Moroi (1998) Journal of Colloid and Interface Science 197:230-235. HERO ID: 1469403

[Less] The solubilization of benzene, toluene, ethylbenzene, n-propylbenzene, n-butylbenzene, n-pentylbenzene, . . . [More] The solubilization of benzene, toluene, ethylbenzene, n-propylbenzene, n-butylbenzene, n-pentylbenzene, n-hexylbenzene, and some arenes into lithium 1-perfluoroundecanoate micelles was measured with increasing the surfactant concentration. Concentrations of all the solubilizates in equilibrium were determined spectrophotometrically at 293.2, 298.2, 303.2, and 308.2 K. The concentration of benzene, toluene, naphthalene, anthracene, and pyrene was not found to increase under the same condition. The first stepwise association constants (K1) between solubilizate monomer and vacant micelle were evaluated from the equilibrium concentration of solubilizate and were found to increase with increasing hydrophobicity of the solubilizate molecules for the alkylbenzenes. The thermodynamic parameters in this system were compared with those for solubilization into 1-dodecanesulfonic acid micelles. These solubilizates were all solubilized on the surface region of the fluorocarbon micelles, which is different from the previous result that the solubilizates with longer alkyl chains were in the inner part of the above-mentioned hydrocarbon micelles. Copyright 1998 Academic Press. Copyright 1998Academic Press

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Influence of carbon chain length on the hepatic effects of perfluorinated fatty acids. A 19F- and 31P-NMR investigation

Authors: Goecke-Flora, CM; Reo, NV (1996) Chemical Research in Toxicology 9:689-695. HERO ID: 2906765

[Less] Using nuclear magnetic resonance (NMR) spectroscopy, we investigated the importance of carbon chain . . . [More] Using nuclear magnetic resonance (NMR) spectroscopy, we investigated the importance of carbon chain length with regard to the hepatic effects associated with perfluoro-n-carboxylic acids. Male F-344 rats were administered a single intraperitoneal dose of either perfluoro-n-heptanoic acid (C7-PFA), perfluoro-n-nonanoic acid (C9-PFA), or perfluoro-n-undecanoic acid (C11-PFA). Data from previous studies involving perfluoro-n-octanoic acid (C8-PFA) and perfluoro-n-decanoic acid (C10-PFA) are included for comparison. Food consumption/body weight was monitored daily for all groups. C9- and C11-PFA treatment yields a prolonged hypophagic response while C7-PFA shows a more acute response. Fluorine-19 NMR spectra of urine and bile samples show no evidence of fluorometabolites and suggest that the distribution of perfluorocarbons into urine or bile is dependent upon carbon chain length. The aqueous solubility of C7-PFA appears to facilitate rapid urinary excretion, similar to that observed for C8-PFA. The relative hydrophobicity of C9- and C11-PFA appears to favor biliary enterohepatic recirculation, yielding a more protracted toxicity, similar to C10-PFA. Phosphorus-31 NMR studies of liver in vivo and liver extracts show that perfluorocarbons of > or = C9 carbons produce a significant increase in liver phosphocholine concentration. These data are discussed with regard to the impact of these chemicals on hepatic phospholipid metabolism. Hepatic peroxisomal fatty acyl CoA-oxidase activity (FAO) was measured to determine if C7-, C9-, and C11-PFA are peroxisome proliferators. Data indicate that the induction of peroxisomal enzyme activity by perfluorocarbons requires a chain length greater than seven carbons. In general, these results demonstrate the significance of carbon chain length in the hepatotoxic response and provide clues toward understanding the processes involved in the biological activities associated with exposure to these compounds.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

STRUCTURAL INVESTIGATIONS OF POLYION COMPLEX LANGMUIR-BLODGETT-FILMS CONTAINING FLUOROCARBON CHAINS

Authors: Kobayashi, K; Takasago, M; Taru, Y; Takaoka, K (1994) HERO ID: 3937166

[Less] The structures of the polyion complex Langmuir-Blodgett (LB) film, in particular the effects of the . . . [More] The structures of the polyion complex Langmuir-Blodgett (LB) film, in particular the effects of the side-chain of the polymer cation on the structure, were investigated by using X-ray diffraction, ellipsometry, Fourier-transform infrared reflection-absorption spectroscopy and contact angle measurement. It was found that the side-chain of polymer cations affects the layered structure and surface structure of polyion complex LB films, and that the LB film of perfluoroundecanoic acid (PFUA)-poly(vinylbenzyltrimethylammonium chloride) containing a longer side-chain has a more disordered structure than those of PFUA-poly(vinylamine) and PFUA-poly(allylamine), which have a well-ordered layered structure.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

STRUCTURAL CHARACTERIZATION OF POLYION COMPLEX LANGMUIR-BLODGETT-FILMS OF PERFLUOROUNDECANOIC ACID-POLYETHYLENEIMINE

Authors: Kobayashi, K; Takaoka, K; Ochiai, S; Taru, Y; Takasago, M (1992) HERO ID: 3937248

[Less] The structural characterization of polyion complex LB films of perfluoroundecanoic acid-polyethyleneimine . . . [More] The structural characterization of polyion complex LB films of perfluoroundecanoic acid-polyethyleneimine was studied using Fourier transform infrared spectroscopy and X-ray photoelectron spectroscopy. From these results, it was found that the fluorocarbon chains in the LB films are located close to the LB film-air interface and are considerably tilted with respect to the surface normal.