Health & Environmental Research Online (HERO)


PFHxA (307-24-4)


326 References Were Found:

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Monolayer Properties of Long-Chain Alkylammonium Perfluorohexanoates on the Concentrated Sodium Chloride Solution

Authors: Shibata,; Moroi,; Saito,; Matuura, (1996) Journal of Colloid and Interface Science 184:175-180. HERO ID: 3859797

[Less] Surface pressure (pi)- and surface potential (DeltaV)-area (A) isotherms were obtained for monolayers . . . [More] Surface pressure (pi)- and surface potential (DeltaV)-area (A) isotherms were obtained for monolayers of alkylammonium perfluorohexanoates of four different alkyl chains (m) on water and 4.4 M NaCl solutions as a function of molecular area of various temperatures by the Langmuir and the ionizing electrode methods. As for octadecylammonium perfluorohexanoate (C18F11), the pi-A curves of these long-hydro-short-fluoro chain salt showed three phase transition points. Judging from the surface potential and the apparent molar quantity together with our previous data on the transitions, the first was assigned to the transition from the expanded (E) phase to the condensed (C-I) phase, the second from the C-I phase to another condensed (C-I') phase, and the third from the (C-I') phase to another condensed (C-II) phase. From the surface potential, the apparent molar entropy change, and the phase diagram, the orientation of long-hydro-short-fluoro chain salts in the monolayer state was discussed.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Perfluorinated acid alternatives to trifluoroacetic acid for reversed-phase high-performance liquid chromatography

Authors: Pearson, JD; Mccroskey, MC (1996) Journal of Chromatography A 746:277-281. HERO ID: 3858375

[Less] Over the past decade trifluoroacetic acid (TFA) has become the ion-pairing agent (IPA) of choice for . . . [More] Over the past decade trifluoroacetic acid (TFA) has become the ion-pairing agent (IPA) of choice for reversed-phase high-performance liquid chromatography (RP-HPLC) of peptides and proteins. Reagent grade TFA is highly pure, water soluble, transparent at 220 nm and readily volatile. A drawback of this universal appeal is that several alternative perfluorinated carboxylic acids tend to be overlooked when TFA does not work in a particular separation. Examples are given comparing TFA selectivity with those of pentafluoropropionic acid, heptafluorobutyric acid, perfluoropentanoic acid, perfluorohexanoic acid and perfluoroheptanoic acid. We have found that increasing the IPA n-alkyl chain length can resolve sample components that otherwise co-elute in the void volume of TFA-based RP-HPLC. Examples are given for the resolution of an oligoglycine series and enhanced selectivity for a bovine hypothalamic extract.

Technical Report
Technical Report

Letter from 3M to USEPA regarding mechanistic two-year study of hepatic tumor induction in rats fed ammonium perfluoroalkyl carboxylates dated 10/11/93

Author: 3M (1993) HERO ID: 3797537

[Less] The test substance included ammonium perfluoroalkyl carboxylates (CAS No. 68259-11-0) which contains . . . [More] The test substance included ammonium perfluoroalkyl carboxylates (CAS No. 68259-11-0) which contains 93 to 97% ammonium perfluorooctanoate (CAS No. 3825-26-1), and smaller amounts of ammonium perfluoroheptanoate (CAS No. 6130-43-4) and ammonium perfluorohexanoate (CAS No. 21615-47-4). The test substance was investigated in a mechanistic bioassay investigating extra hepatic tumor induction by compounds which induce peroxisome proliferation. In this mechanistic bioassay, 300 ppm of the test substance was fed to rats as part of their diet for 2-years. In addition to an ad libitum control, a second control group was pair-fed to the 300 ppm test group to control for the effects of reduced body weight. Increased incidences of combined (single, multiple) hepatic adenomas, Leydig cell adenomas, and pancreatic acinar cell adenomas were seen in the 300 ppm test group when compared to either the ad libitum or pair-fed controls. The tumor incidences (liver, testis, pancreas) were outside the historical control incidence range for DuPont Haskell Laboratory. In addition, age- adjustment statistics also support the conclusion that the tumor incidence was elevated for the liver (both controls), pancreas (pair-fed control), and testis (pair-fed control).

Technical Report
Technical Report

Support: Letter from 3M to USEPA regarding mechanistic two-year study of hepatic tumor induction in rats fed ammonium perfluoroalkyl carboxylates dated 101193

Author: Haskell Laboratories (1993) (Doc# 89-941000007). St. Paul, MN: 3M Company. HERO ID: 3797581

[Less] The test substance included ammonium perfluoroalkyl carboxylates (CAS No. 68259-11-0) which contains . . . [More] The test substance included ammonium perfluoroalkyl carboxylates (CAS No. 68259-11-0) which contains 93 to 97% ammonium perfluorooctanoate (CAS No. 3825-26-1), and smaller amounts of ammonium perfluoroheptanoate (CAS No. 6130-43-4) and ammonium perfluorohexanoate (CAS No. 21615-47-4). The test substance was investigated in a mechanistic bioassay investigating extra hepatic tumor induction by compounds which induce peroxisome proliferation. In this mechanistic bioassay, 300 ppm of the test substance was fed to rats as part of their diet for 2-years. In addition to an ad libitum control, a second control group was pair-fed to the 300 ppm test group to control for the effects of reduced body weight. Increased incidences of combined (single, multiple) hepatic adenomas, Leydig cell adenomas, and pancreatic acinar cell adenomas were seen in the 300 ppm test group when compared to either the ad libitum or pair-fed controls. The tumor incidences (liver, testis, pancreas) were outside the historical control incidence range for DuPont Haskell Laboratory. In addition, age- adjustment statistics also support the conclusion that the tumor incidence was elevated for the liver (both controls), pancreas (pair-fed control), and testis (pair-fed control).

Technical Report
Technical Report

Acute oral toxicity screen with T-2712CoC in albino rats. Experiment no. 0479AR0680

Author: Riker Labs (1979) (8EHQ-04-15674A; 88040000247). St. Paul, MN: 3M Company. [TSCA Submission] HERO ID: 3921144


Technical Report
Technical Report

Read-across for 90-day rat oral repeated-dose toxicity for selected perfluoroalkyl acids: A case study

Authors: Schultz, T.W.; Mellor, C.; Przybylak, K.; Escher, S; Judson, R.; Tsakovka, I.; and Richarz, A. European Chemicals Agency. HERO ID: 3878944