Health & Environmental Research Online (HERO)


PFHxS (355-46-4)


810 References Were Found:

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Hypothalamic sites sensitive to morphine and naloxone: effects on feeding behavior

Authors: Woods, JS; Leibowitz, SF (1985) Pharmacology, Biochemistry and Behavior 23:431-438. HERO ID: 4240590

[Less] Three experiments investigated the feeding response of brain cannulated rats to hypothalamic injection . . . [More] Three experiments investigated the feeding response of brain cannulated rats to hypothalamic injection of norepinephrine (NE), the opiate agonist morphine sulfate (MO) and the opiate antagonist naloxone (NAL). Morphine elicited feeding in a dose-dependent manner when injected into the paraventricular nucleus (PVN) of satiated rats, at doses of 0.78 to 100 nmoles, with a threshold dose of 1.56 nmoles. Naloxone, at doses of 3.13 to 200 nmoles, was injected into the PVN of food-deprived rats and was found to produce a dose-dependent suppression of feeding (threshold dose of 6.25 nmoles). Animals with brain cannulas aimed at the PVN, the perifornical hypothalamus (PFH), the dorsomedial (DMN) and ventromedial (VNM) nuclei were compared for their sensitivity to the feeding stimulatory effects of NE and MO (except in the DMN) and the feeding suppressive effects of NAL. Consistent with earlier reports, the PVN-cannulated animals exhibited a reliable increase in feeding after NE injection; the VMN cannula yielded a small feeding response, whereas the DMN and PFH were insensitive to NE. Morphine, in contrast, strongly stimulated eating after administration into PFH, as well as the PVN, apparently dissociating the NE and MO eating responses. The VMN, however, was generally unresponsive to both MO and NE. With regard to NAL's suppressive effect on feeding, the PVN and PFH, which were sensitive to MO, also exhibited responsiveness to opiate antagonism suggesting the existence in these areas of opiate receptors that modulate feeding.(ABSTRACT TRUNCATED AT 250 WORDS)

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Determination of the course of brainstem catecholamine fibers mediating amphetamine anorexia

Authors: Mccabe, JT; Leibowitz, SF (1984) Brain Research 311:211-224. HERO ID: 4240587

[Less] Previous studies suggest that brainstem catecholamine (CA) fibers which mediate amphetamine (AMPH)-induced . . . [More] Previous studies suggest that brainstem catecholamine (CA) fibers which mediate amphetamine (AMPH)-induced anorexia ascend through the midlateral medical forebrain bundle and perifornical region and terminate in the perifornical hypothalamic region (PFH) at the level of the hypothalamic ventromedial nucleus. Through studies of wire-knife cuts (KCs) placed in the lower brainstem, the present paper further delineates the course of fibers mediating AMPH feeding suppression, as they ascend through the medullary, pontine and midbrain tegmentum. The results indicate that the crucial CA fibers ascend through the ventrolateral medulla just dorsal to the nucleus of the seventh cranial nerve, 1.1-1.9 mm lateral to midline. In their rostral course, these fibers apparently maintain a relatively straight position in the ventral pons and then enter the ventrolateral midbrain just dorsal to the medial lemniscus, between 0.7 and 1.1 mm lateral to midline. These medullary fibers, possibly originating from the norepinephrine/epinephrine-containing ventrolateral cell group (A1/C1), then appear to join additional fibers from the scattered dopamine-containing neurons positioned in the caudal midbrain (A8 CA cell group). Together, these dopamine, epinephrine and norepinephrine systems are believed to ascend into the medial aspect of the medial forebrain bundle on their way to the PFH at the level of the ventromedial nucleus.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

In Vitro Screening Of The Effect Of Hydrazine Derivatives On Hepatic Aryl Hydrocarbon Hydroxylase Activity

Authors: Al-Turk, WA; Raha, CR; Murray, WJ; Heinicke, RJ (1983) HERO ID: 4240422

[Less] The effects of 14 hydrazine derivatives on hepatic microsomal arylhydrocarbon-hydroxylase (AHH) activity . . . [More] The effects of 14 hydrazine derivatives on hepatic microsomal arylhydrocarbon-hydroxylase (AHH) activity were studied in-vitro. The following compounds were tested at 0, 0.1, 2, 3, or 4 millimolar (mM): hydrazine-hydrate (7803578) (HH); methylhydrazine (60344) (MH); 1,1-dimethylhydrazine (57147) (1,1-DMH); 1-methyl-1-formylhydrazine (MFH); 1-propyl-1-formylhydrazine (PFH); 1,1-dipropylhydrazine (1,1-DPH); 1,1-diallylhydrazine (1,1-DAH); 1,1-dibutylhydrazine (1,1-DBH); 1,2-dimethylhydrazine (540738) (1,2-DMH); 1,2-diallylhydrazine (1,2-DAH); 1,2-dibutylhydrazine (1,2-DBH); phenylhydrazine (PH); 1-acetyl-2-p-(hydroxy-methyl)-phenylhydrazine (AHMPH); and 1-gamma-glutamyl-2-p-(hydroxy-methyl)-phenylhydrazine (GHMPH). Fresh liver microsomes were obtained from Sprague-Dawley-rats and incubated with the hydrazines at 0 to 4 millimolar (mM) in trisodium-isocitrate, magnesium-chloride, isocitrate-dehydrogenase, and benzo(a)pyrene; AHH activity was assayed spectrophotofluorometrically. At 0.1mM, significant decreases in AHH activity were seen for 1,1-DMH; 1,1-DAH; 1,1-DBH; and PH. At 1mM, significant decreases were seen for HH; MFH; PFH; 1,1-DPH; 1,2-DAH; 1,2-DBH; AHMPH; and GHMPH. Significant decreases were seen for 1,2-DMH at 2mM and MH at 4mM. PH was the most potent compound tested, with 85 percent inhibition at 0.1mM. The authors conclude that all the hydrazine derivatives tested inhibit hepatic AHH activity; the degree of inhibition is dependent on concentration and structure.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Ovulation induction with intermittent subcutaneous LHRH

Authors: Keogh, EJ; Mallal, SA; Giles, PFH; Evans, DV (1981) HERO ID: 4240387

[Less] IPA COPYRIGHT: ASHP The case of an anovulatory infertile patient who successfully conceived after . . . [More] IPA COPYRIGHT: ASHP The case of an anovulatory infertile patient who successfully conceived after intermittent SC administration of luteinizing hormone releasing hormone (gonadorelin; I) into the abdominal wall via a scalp vein needle using a programmed, battery operated, syringe driver is presented.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Tumorigenesis by N-n-propyl-N-formylhydrazine in mice

Authors: Toth, B; Nagel, D; Patil, K (1980) British Journal of Cancer 42:922-928. HERO ID: 4240348

[Less] HEEP COPYRIGHT: BIOL ABS. Continuous administration of 0.04% N-n-propyl-N-formylhydrazine (PFH) for . . . [More] HEEP COPYRIGHT: BIOL ABS. Continuous administration of 0.04% N-n-propyl-N-formylhydrazine (PFH) for life in drinking water to 6 wk old randomly bred Swiss mice induced tumors of the lungs, preputial glands, liver and gall bladder. The tumor incidences in these 4 tissues were 91, 22, 8 and 6%; in the untreated controls they were 25, 0, 0.5 and 0.5%, respectively. The higher dose of 0.08% PFH, given under identical conditions, induced only tumors of the lungs, liver and gall bladder in lower incidences, since the compound was too toxic for the mice. Histopathologically, the tumors were classified as adenomas and adenocarcinomas of the lungs, squamous cell papillomas, carcinomas and fibrosarcoma of preputial glands, benign hepatomas, liver cell carcinoma and adenomas and adenocarcinoma of the gall bladder. The investigation is part of a structure/activity relationship inquiry aimed at revealing the mechanism of action of the N-alkyl-N-formylhydrazine series of chemicals.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

A PFHS (PRECIPITATION FROM HOMOGENEOUS SOLUTIONS) METHOD FOR GRAVIMETRIC ESTIMATION OF GALLIUM(III) AND INDIUM(III)

Authors: Kakkar, KK; Rupainwar, DC (1976) HERO ID: 4240883


Technical Report
Technical Report

Precipitation of mercury sulfide from homogeneous solution. Graveimetric determination of mercury

Author: Vassiliades GS CVVasilikiotis (1969) HERO ID: 1370766

[Less] HAPAB A rapid, selective semimicro gravimetric method for the determination of mercury is presented. . . . [More] HAPAB A rapid, selective semimicro gravimetric method for the determination of mercury is presented. The method takes advantage of the principle of precipitation from homogenous solution ( PFHS ). Of various compounds tested. N-allylothio-urea ( ATU ) was found to be a good PHFS reagent for mercury. The sample of mercury as mercuric chloride was reacted with a six-fold excess of ATU over mercury. After heating to 60 C, ammonium hydroxide solution was added to obtain a pH of 9. The black precipitate ( mercury sulfide ) which was formed was washed, dried and weighed for mercury determination. Mercury, in quantities of 2 to 100 mg, was determined in 12 samples without impurities and in 11 samples in the presence of diverse ions, with a mean relative error of less than 1%. The reagent appears to be selective for mercury in the presence of masking agents, which do not prevent the precipitation of mercury sulfide. The following anions, tested in the form of their sodium, ammonium and potassium salts, do not interfere with the analysis; acetate, arsenate, arsenite, carbonate, chloride, citrate, ferrocyanate, nitrate, nitrite, sulfate, tartrate, thiocyanate and thiosulfate; cyanide, iodide and phosphte do interfere. Of those cations which form insoluble sulfides, only silver interfere. Analysis 69/10/00, 366 1969

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Gravimetric determination of nickel with quinoxaline-2,3-dithiol by precipitation from homogeneous solution

Authors: Dalziel, JA; Slawinski, AK (1968) HERO ID: 4240324

[Less] The investigation of quinoxaline-2,3-dithiol as a gravimetric reagent for nickel is described. A derivative . . . [More] The investigation of quinoxaline-2,3-dithiol as a gravimetric reagent for nickel is described. A derivative of the dithiol, S-2-(3-mercaptoquinoxalinyl)thiuronium chloride is used as a generating agent in a PFHS method because of its relative stability and solubility in aqueous ethanol. Nickel, 2.5-25.0 mug, can be precipitated at pH 2-3 as (C(8)H(5)N(2)S(2))(2)Ni. After filtration the precipitates are washed first with aqueous ethanol to remove traces of absorbed reagent and then with benzene to remove a small amount of decomposition product of the reagent, the characterization of which is described. The precipitates are stable and can be dried in air at 110-120 degrees . Errors of less than 0.15 % are obtained in the analysis of solutions containing 25 mg of nickel. The selectivity of the reagent is discussed and some suggestions are made for masking the interference of other elements.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

On homogeneous nucleation in barium sulphate precipitation from homogeneous solution

Authors: Mealor, D; Townshend, A (1966) HERO ID: 4240325

[Less] Unsuccessful attempts to induce homogeneous nucleation of barium sulphate by a PFHS technique in which . . . [More] Unsuccessful attempts to induce homogeneous nucleation of barium sulphate by a PFHS technique in which potential hetero-nuclei are removed by a preliminary precipitation are described. In all instances, only heterogeneous nucleation was observed.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

A comparative study of methods for precipitating calcium oxalate from homogeneous solution

Authors: Bashar, A; Townshend, A (1966) Talanta 13:1123-1128. HERO ID: 4240326

[Less] A PFHS of calcium oxalate has been examined and the optimum conditions for the precipitation established. . . . [More] A PFHS of calcium oxalate has been examined and the optimum conditions for the precipitation established. This method, and two other methods employing PFHS for the gravimetric determination of calcium as the oxalate are compared with the conventional and acetic acid-medium methods. All the methods work well in the absence of magnesium, but the urea hydrolysis procedure, in the absence of an initial precipitate, is recommended as the best method when magnesium is present. Crystal sizes have been measured by microscopy.