Health & Environmental Research Online (HERO)


Malonates (108-58-8 & 105-53-3)


196 References Were Found:

Technical Report
Technical Report

Chemview: genetic toxicity in vivo: test substance: 95481-62-2. Dibasic Ester.

Author: EPA (1988) HERO ID: 5097554


Technical Report
Technical Report

Reaction mass of 1,5-dimethyl glutarate, 1,6-dimethyl adipate and 1,4-dimethyl succinate: repeated dose toxicity: inhalation: 003 supporting | experimental result

Author: ECHA (1987) Helsinki, Finland: ECHA. HERO ID: 5097458


Technical Report
Technical Report

90-day inhalation toxicity study in rats with dibasic esters (DBE) - 2 with attachments and cover letter dated 120187

Author: E I Dupont De Nemours & Co (1987) (589). HERO ID: 5097737


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Sorption-desorption phenomena of chemicals from polymer paint films

Authors: Schwope, AD; Klein, J; Sidman, KR; Reid, RC (1986) Journal of Hazardous Materials 13:353-368. HERO ID: 4931349

Abstract: Biosis copyright: biol abs. rrm human personnel skin diethylmalonate toxic chemicals model

Book/Book Chapter
Book/ Chapter

Diethyl malonate

(1986) In Geiger, DL; Poirier, SH; Brooke, LT; Call, DJ (Eds.), Acute toxicities of organic chemicals to fathead minnows (Pimephales promelas): Volume III (pp. 177-178). Superior, WI: University of Wisconsin-Superior, Center for Lake Superior Environmental Studies. HERO ID: 4939288


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Effect of various growth conditions on spore formation and bacillomycin L production in Bacillus subtilis

Authors: Chevanet, C; Besson, F; Michel, G (1986) Canadian Journal of Microbiology 32:254-258. HERO ID: 4923751

[Less] Bacillomycin L is produced by Bacillus subtilis NCIB 8872 in the stationary phase; it is excreted into . . . [More] Bacillomycin L is produced by Bacillus subtilis NCIB 8872 in the stationary phase; it is excreted into the culture medium, without prior accumulation in the bacterial cells. The production of bacillomycin L is largely dependent on the composition of the culture medium. The action of specific inhibitors of sporulation, netropsin and diethyl malonate, on antibiotic synthesis is dependent on the composition of the culture medium. Although they occurred at the same time, there appears to be no direct correlation between sporulation and antibiotic synthesis.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Comparative metabolism and mutagenicity of azo and hydrazone dyes in the Ames test

Authors: De France, BF; Carter, MH; Josephy, PD (1986) Food and Chemical Toxicology 24:165-169. HERO ID: 625777

[Less] Enteric bacterial and hepatic azoreductase enzymes are capable of reducing azo dyes to yield the constituent . . . [More] Enteric bacterial and hepatic azoreductase enzymes are capable of reducing azo dyes to yield the constituent aromatic amines. Azo dyes based on benzidine and benzidine congeners have received particular attention because of their widespread use and the known carcinogenicity of benzidine to humans. Azo dyes based on beta-diketone coupling components exist preferentially as the tautomeric hydrazones. A series of hydrazone dyes based on benzidine and benzidine congeners was prepared and characterized by NMR and UV-visible spectroscopy. These dyes were tested for mutagenicity using a modified Ames assay and, unlike the true azo dyes, showed no significant mutagenic activity. The hydrazone dyes were resistant to enzymatic reduction by FMN-supplemented hamster-liver post-mitochondrial supernatant (S-9); under identical conditions, azo dyes such as trypan blue were rapidly reduced.

Book/Book Chapter
Book/ Chapter

Diethyl malonate

(1985) In Geiger, DL; Northcott, CE; Call, DJ; Brooke, LT (Eds.), Acute toxicities of organic chemicals to fathead minnows (Pimephales promelas): Volume II (pp. 169-170). Superior, WI: University of Wisconsin-Superior, Center for Lake Superior Environmental Studies. HERO ID: 4939484


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Effects of propionate and methylmalonate on conversions of acetate, butyrate, and D(-)-3-hydroxybutyrate to fatty acids and carbon dioxide by mammary tissue slices of goats

Authors: Emmanuel, B; Kennelly, JJ (1985) Journal of Dairy Science 68:751-754. HERO ID: 4923760

[Less] Incorporations of [1-carbon-14] acetate, [1-carbon-14] propionate, n-[1-carbon-14] butyrate, and D(-)-3-hydroxy[3-carbon-14] . . . [More] Incorporations of [1-carbon-14] acetate, [1-carbon-14] propionate, n-[1-carbon-14] butyrate, and D(-)-3-hydroxy[3-carbon-14] butyrate into individual milk fatty acids and their conversion to carbon dioxide were studied in vitro with caprine mammary tissue slices in the presence and absence of propionate and methylmalonate. Neither propionate nor methylmalonate affected incorporation of these substances into fatty acids. In a decreasing order butyrate, acetate, propionate, and D(-)-3-hydroxybutyrate were converted to carbon dioxide. Acetate had the highest incorporation rate into fatty acids followed by D(-)-3-hydroxybutyrate, butyrate, and propionate. Labeled propionate was incorporated mainly into odd-numbered fatty acids. Results do not support the theory that either propionate or its metabolite, methylmalonate, inhibit de novo synthesis of fatty acids in the mammary gland in relation to the etiology of low milk fat syndrome.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Suppression of granulopoietic progenitor cell proliferation by metabolites of the branched-chain amino acids

Authors: Hutchinson, RJ; Bunnell, K; Thoene, JG (1985) Journal of Pediatrics 106:62-65. HERO ID: 4923763

[Less] The effects of branched-chain amino acid metabolites on granulocyte-macrophage progenitor cell proliferation . . . [More] The effects of branched-chain amino acid metabolites on granulocyte-macrophage progenitor cell proliferation in marrow culture are reported. Isovalerate and propionate profoundly suppress granulopoiesis at both 3.2 and 6.4 mM concentrations, whereas methylmalonate and other metabolites suppress to a lesser degree. The parent branched-chain amino acids leucine, isoleucine, and valine do not suppress in vitro granulopoiesis at similar concentrations. Because the concentrations of the organic acids tested fall within the pathophysiologic ranges observed in patients with isovaleric, propionic, and methylmalonic acidemias, we suggest that elevated in vivo levels of isovalerate, propionate, and to a lesser degree methylmalonate are responsible for the neutropenia observed in these disorders.