Health & Environmental Research Online (HERO)


Fatty alcohols (112-92-5, 661-19-8, 629-96-9, & 143-28-2)


599 References Were Found:

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Allergic contact dermatitis caused by sodium cetearyl sulfate

Authors: Oscoz-Jaime, S; Hervella-Garcés, M; M de Espronceda-Ezquerro, I; Yanguas-Bayona, JI (2018) Contact Dermatitis 78:426-427. HERO ID: 4929238


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Cetearyl isononanoate, an underestimated contact allergen?

Authors: Álvarez-Chinchilla, P; Poveda-Montoyo, I; González, I; Silvestre, JF (2018) Contact Dermatitis 79:243-244. HERO ID: 4929244


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Synthesis of Phosphoester Compounds Using Lactic Acid for Encapsulation of Paclitaxel

Authors: Takeuchi, I; Mikuni, R; Makino, K (2018) Anticancer Research 38:3401-3406. HERO ID: 4929236

[Less] BACKGROUND/AIM: In the use of paclitaxel, side-effects caused by itself or solubilizing . . . [More] BACKGROUND/AIM: In the use of paclitaxel, side-effects caused by itself or solubilizing agents have become a major obstacle. In this study we aimed to synthesize biocompatible and degradable compounds for micelles to be used as carriers for paclitaxel.

MATERIALS AND METHODS: Methoxypolyethylene glycol-lactate was obtained from methyl lactate and methoxypolyethylene glycol having a molecular weight of 350. Monoalkoxy phosphoryl chlorides were obtained from phosphoryl chloride and four kinds of linear alcohols. Then, four kinds of alkyl di(methoxypolyethylene glycol-lactate) phosphates were obtained from them.

RESULTS: The results of 1H NMR spectroscopy showed that alkyl di(methoxypolyethylene glycol-lactate) phosphates were successfully synthesized. When 1-dodecanol, 1-hexadecanol, 1-octadecanol, and 1-eicosanol were used as side chains, the yields were 73.5±4.2, 69.1±3.6, 72.2±2.8, and 71.8±3.7%, respectively. The spectrum of 31P NMR suggested the existence of optical isomers.

CONCLUSION: Four kinds of phosphoester compounds for micelle preparations were synthesized using lactic acid.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Development and validation of a bioanalytical method for quantification of LNA-i-miR-221, a 13-mer oligonucleotide, in rat plasma using LC-MS/MS

Authors: Franzoni, S; Vezzelli, A; Turtoro, A; Solazzo, L; Greco, A; Tassone, P; Di Martino, MT; Breda, M (2018) Journal of Pharmaceutical and Biomedical Analysis 150 (February 20:300-307. HERO ID: 4942604

[Less] LNA-i-miR-221, a 13-mer oligonucleotide, is a new miR-221 inhibitor that could be used as a novel drug . . . [More] LNA-i-miR-221, a 13-mer oligonucleotide, is a new miR-221 inhibitor that could be used as a novel drug for multiple myeloma. Herein, an ion-pair reversed phase liquid chromatography-tandem mass spectrometry (LC-MS/MS) method has been developed and validated for the quantification of LNA-i-miR-221 in rat plasma. Plasma samples were prepared with an initial phenol/chloroform/isoamyl alcohol liquid-liquid extraction followed by a solid phase extraction. Chromatographic separation was performed with a gradient system on a HALO C18 column using hexafluoro-2-propanol/triethylamine buffer and methanol as mobile phase at a flow rate of 0.4 mL/min. Under these conditions LNA-i-miR-221 and the analogue internal standard are co-eluted at 1.2 min. The detection was carried out in multiple reaction monitoring (MRM) mode using a negative electrospray ionization (ESI) interface. The assay showed a good linearity within the calibration range 10-10000 ng/mL. The precision, accuracy, and recovery values were found to be <15% (<20% at LLOQ), 100 ± 15%, and 97.6-103.7%, respectively. This method was successfully applied to measure the concentrations of LNA-i-miR-221 in plasma samples following the intravenous administration during a 4-week toxicity study in rats.

Journal Article
Journal Article

Chemical composition and antifungal effect of hydroalcoholic extract of Allium tripedale (Tvautv.) against Candida species

Authors: Shirani, M; Samimi, A; Kalantari, H; Madani, M; Kord Zanganeh, A (2017) HERO ID: 4929259

[Less] Background and Purpose: Treatment of life-threatening fungal infections caused by Candida . . . [More] Background and Purpose: Treatment of life-threatening fungal infections caused by Candida species has become a major problem. Candida spp. are the most important causative agents of candidiasis. Allium tripedale is a medicinal plant that has been traditionally used to treat infections. In the present study, we aimed to determine the chemical compounds and antimicrobial activity of hydroalcoholic extract of A. tripedale against different species of Candida.

Materials and Methods: Phytochemical analysis was performed to identify the possible bioactive components of this extract by using gas chromatography and mass spectroscopy (GC-MS). The hydroalcoholic extract of A. tripedale were collected. Different concentrations of A. tripedale (50, 25, 12.5, and 6.25 mg/ml) were used to evaluate its antifungal activity against Candida species (C. albicans, C. parapsilosis, and C. krusei) using disk diffusion assay.

Results: The GC-MS analysis revealed the presence of 40 different phytoconstituents with peak area; the major compounds were tetracosane, hexadecanoic acid, 1-eicosanol, 1,2-dihydro-pyrido[3,2,1-kl]phenothiazin-3-one, 2-hexadecen-1-ol, and 3,7,11,15-tetramethyl. Hydroalcoholic extract showed strong antimicrobial activity (inhibition zone ⩾ 20 mm), moderate antimicrobial activity (inhibition zone < 12-20 mm), and no inhibition (zone < 12 mm). In addition, the hydroalcoholic extract exhibited the highest antimicrobial properties against C. albicans strains.

Conclusion: A. tripedale extract had a considerable inhibitory effect against various Candida species, but its highest inhibitory effect was against Candid albicans. Further investigations are required to detect the performance of this plant in the treatment of Candida infection.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Molecular biosignatures reveal common benthic microbial sources of organic matter in ooids and grapestones from Pigeon Cay, The Bahamas

Authors: O'Reilly, SS; Mariotti, G; Winter, AR; Newman, SA; Matys, ED; Mcdermott, F; Pruss, SB; Bosak, T; Summons, RE; Klepac-Ceraj, V (2017) HERO ID: 3846363

[Less] Ooids are sedimentary grains that are distributed widely in the geologic record. Their formation is . . . [More] Ooids are sedimentary grains that are distributed widely in the geologic record. Their formation is still actively debated, which limits our understanding of the significance and meaning of these grains in Earth's history. Central questions include the role played by microbes in the formation of ooids and the sources of ubiquitous organic matter within ooid cortices. To address these issues, we investigated the microbial community composition and associated lipids in modern oolitic sands at Pigeon Cay on Cat Island, The Bahamas. Surface samples were taken along a transect from the shallow, turbulent surf zone to calmer, deeper water. Grains transitioned from shiny and abraded ooids in the surf zone, to biofilm-coated ooids at about 3 m water depth. Further offshore, grapestones (cemented aggregates of ooids) dominated. Benthic diatoms and Proteobacteria dominated biofilms. Taxa that may promote carbonate precipitation were abundant, particularly those associated with sulfur cycling. Compared to the lipids associated with surface biofilms, relict lipids bound within carbonate exhibited remarkably similar profiles in all grain types. The enhanced abundance of methyl-branched fatty acids and β-hydroxy fatty acids, 1-O-monoalkyl glycerol ethers and hopanoids bound within ooid and grapestone carbonate confirms a clear association of benthic sedimentary bacteria with these grains. Lipids bound within ooid cortices also contain molecular indicators of microbial heterotrophic degradation of organic matter, possibly in locally reducing conditions. These included the loss of labile unsaturated fatty acids, enhanced long-chain fatty acids/short-chain fatty acids, enriched stable carbon isotopes ratios of fatty acids, and very high stanol/stenol ratios. To what extent some of these molecular signals are derived from later heterotrophic endolithic activity remains to be fully resolved. We speculate that some ooid carbonate forms in microbial biofilms and that early diagenetic degradation of biofilms may also play a role in early stage carbonate precipitation around ooids.

Journal Article
Journal Article

Essential Oil from the Leaves of Ajuga iva: Chemical Composition and Antimicrobial Activity

Authors: Chouitah, O; Meddah, B; Aoues, A; Sonnet, P (2017) HERO ID: 4937375

[Less] The leaf essential oil of Ajuga iva growing wild in Mascara region situated in the North West of Algeria, . . . [More] The leaf essential oil of Ajuga iva growing wild in Mascara region situated in the North West of Algeria, has been obtained by hydrodistillation and analyzed by GC and GC-MS. We proposed to determine the physicochemical, organoleptic and chemical identification of these components. Twenty two volatile compounds were identified which included: dienestrol (54.04%), eucalyptol (27%), o-xylene (7.98 %), 1-octadecanol (5.80%); 3-carene (4.46%), (E)-2,3,6- trimethoxypentafulvene-1-carbonitrile (4.34%), (-)-spathulenol (1.77%), nonanal (1.24%). The oil from Ajuga iva showed activities against Escherichia coli, Salmonella typhimurium, Staphylococcus aureus,Bacillus subtilis, and Pseudomonas aeroginosa.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Allergic contact dermatitis caused by wet wipes containing steareth-10: Is stearyl alcohol to blame?

Authors: Aerts, O; Naessens, T; Dandelooy, J; Leysen, J; Lambert, J; Apers, S (2017) Contact Dermatitis 77:117-119. HERO ID: 4929237

[Less] Steareths, such as steareth-10 (CAS no. 9005-00-9/13149-86-5), are emulsifiers that are apparently associated . . . [More] Steareths, such as steareth-10 (CAS no. 9005-00-9/13149-86-5), are emulsifiers that are apparently associated with a low risk of sensitization. They are prepared by the chemical reaction of ethylene oxide with stearyl alcohol, and the numerical suffix indicates the average number of ethylene oxide units used. We here report a rare case of allergic contact dermatitis caused by steareth-10 present in makeup-removing wet wipes, and we discuss the residual presence of stearyl alcohol in these wipes as a potential culprit.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Phytochemical profile, antimicrobial potential and GC-MS analysis of wild variety of Olea Europaea (Olive) cultivated in Pakistan

Authors: Ahmad, W; Ali, N; Afridi, MS; Rahman, H; Adnan, M; Ullah, N; Muhammad, U; Ilyas, M; Khan, H (2017) Pure and Applied Biology 6:337-345. HERO ID: 4941774

[Less] Olive plant produces a variety of bioactive molecules and thus has important medicinal value in folk . . . [More] Olive plant produces a variety of bioactive molecules and thus has important medicinal value in folk medicine. In this study, different leaf and fruit extracts of Pakistani wild variety of Olea europaea was tested for their phytochemical content, antimicrobial activity and mass spectrometric analysis. Olive leaves and fruit samples were extracted with five different solvents to obtain the crude extract and screened for various kinds of phytochemicals. Phytochemicals were further confirmed through Fourier Transmission Infra-red Spectroscopy (FTIR). The plant extract showed significant antimicrobial activity against all the strains tested. Methanol, ethanol and ethyl acetate extracts were found more effective against most of the pathogenic bacteria with high zone of inhibition. Gas Chromatography-Mass Spectrometry (GC-MS) analysis revealed that olive fruits have Oleic acid, Palmitic acid, Linoleic acid, Octadecadienoic acid, Stearic acid, Palmitoleic acid and Tridecanoic acid as oil contents. In this work, the antimicrobial potential and phytochemical contents were explored which may further pave the way for the bio-industrial applications.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Oxidative decomposition of thin films of oleyl and stearyl alcohols on steel surface

Authors: Brazinskiene, D; Straksys, A; Voisniene, V; Vilkauskaite, R; Asadauskas, S (2017) Lietuvos Mokslu Akademija. Chemija 28:1-8. HERO ID: 4657051

[Less] Fatty alcohols and their derivatives are popular additives in shampoos, cosmetics, paints, lubricants . . . [More] Fatty alcohols and their derivatives are popular additives in shampoos, cosmetics, paints, lubricants and other functional fluids, whose films are exposed to the environment. Often these films degrade due to oxidative, thermal, catalytic and other stress factors, producing volatile emissions. Decomposition of fatty materials is rarely viewed as a significant contributor to vapour losses, however, it cannot be assumed that fatty alcohols are completely non-volatile. In this study, oxidative degradation of thin films of oleyl and stearyl alcohols was investigated on the steel surface. Tests at 90 degrees C showed that within several hours significant portions of these alcohols were lost to volatile emissions. Initially the absolute evaporation rates did not depend on the film thickness and appeared quite similar for both alcohols. In later stages, the evaporation rate of thinner films went down due to the formation of oxidative polymers and functional group oxidation. Acidity of oleyl alcohol increased much more rapidly than that of stearyl. After long-term degradation oleyl alcohol produced gel-like solids, while films of stearyl alcohol began to retain a liquid state at room temperature. Since the volatile emissions amounted to more than 60%, the decomposition products in final applications should be investigated in more detail when stearyl or oleyl alcohols are used as major constituents in commercial liquids.