Health & Environmental Research Online (HERO)


Fatty alcohols (112-92-5, 661-19-8, 629-96-9, & 143-28-2)


587 References Were Found:

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Metabolism of sperm oil in rats: II. Seborrhea caused by waxes with different carbon atom chain

Authors: Sato, Y; Tsuchiya, Y (1977) Nippon Suisan Gakkaishi 43:1129-1131. HERO ID: 4942469

[Less] Rats were fed with a basal diet to which an ester of oleic acid with C8 to C18 saturated alcohols and . . . [More] Rats were fed with a basal diet to which an ester of oleic acid with C8 to C18 saturated alcohols and a C18 unsaturated alcohol was added in the ratio f 10 and 15 per cent. A mild sign of seborrhea was manifested in rats with hexadecyl- and octadecyl-oleates. On the contrary, the animals with octadecenyl-oleate had abnormal scour for several successive days from the third or fourth day of the experiment. They were smudged with the fatty excrements and frequently mistaken for the animals suffering from seborrhea. They became emaciated and soon died.

Journal Article
Journal Article

Zur speziesabhangigkeit der hautvertraglichkeit von kosmetikgrundstoffen

Author: Kastner W (1977) HERO ID: 4949204


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Effects of lipids on bioavailability of sulfisoxazole acetyl, dicumarol, and griseofulvin in rats

Authors: Bloedow, DC; Hayton, WL (1976) HERO ID: 4932656

[Less] The effects of hexadecane, oleyl alcohol, polysorbate 80, trioctanoin, and triolein on the bioavailability . . . [More] The effects of hexadecane, oleyl alcohol, polysorbate 80, trioctanoin, and triolein on the bioavailability of sulfisoxazole N1-acetyl, dicumarol, and griseofulvin were investigated. Compared to administration of the drugs in water, the rate of absorption of the drugs was either decreased or not changed by the lipids. The extent of absorption of sulfisoxazole acetyl and dicumarol was significantly increased by polysorbate 80 and triolein and not affected by hexadecane or oleyl alcohol. Tricotanoin increased the extent of abosrption of sulfisoxazole acetyl but had no effect on the absorption of dicumarol. Compared to the aqueous vehicle, the extent of absorption of greiseofulvin was decreased by hexadecane, oleyl alcohol, and triolein, increased by polysorbate 80, and not affected by trioctanoin. The extent of absorption of sulfisoxazole acetyl was not affected by the amount of triolein in which it was administered nor by emulsification of triolein prior to administration.

Meeting/Symposium
Presentation

Chain-length specificity in ether lipid biosynthesis - Presence and metabolism of 1-docosanol in myelinating rat-brain

Authors: Natarajan, V; Schmid, HHO (1976) Abstracts of Papers - American Chemical Society 172:172. [Abstract] HERO ID: 4936392

[Less] Long-chain alcohols are known to be the precursors of both alkyl and alk-1-enyl moieties of ether lipids . . . [More] Long-chain alcohols are known to be the precursors of both alkyl and alk-1-enyl moieties of ether lipids in biological systems including the mammalian brain. In recent investigations on the levels of free longchain alcohols in rat brain at different stages of postnatal development, we detected relatively large amounts of 1-docosanol, comprising up to 20% of the total alcohols. Since rat brain ether lipids do not contain alkyl or alk-1 enyl moieties of more than 18 carbon atoms, the metabolism of docosanol relative to other fatty alcohols was investigated. Simultaneous intracerebral injection of (1-14cJdocosanol and [l-14c]octadecenol showed that both alcohols were oxidized to the corresponding fatty acids. However, only octadecenol served as substrate for alkylglycerol synthesis within a 24 hr period. Subcellular preparations of developing rat brain were used to study the reduction of fatty acids of different chain lengths to the corresponding alcohols, and the formation of the ether bond from such alcohols in vitro. Although previous work from this laboratory has shown that a variety of structural analogs of fatty alcohols can serve as alkyl donors in ether lipid biosynthesis, the present data indicate a distinct chain-length specificity for this reaction.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Contact dermatitis from stearyl alcohol in Metosyn (Fluocinonide) Cream

Author: Black, H (1975) Contact Dermatitis 1:125. HERO ID: 4929626


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

[Preventive action of some detergents in experimental carbon tetrachloride poisoning]

Author: Zajusz, K (1975) HERO ID: 4932660


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

[Fatty-acid pattern of human fat and liver tissues in alcoholics and non-alcoholics: fatty-acid pattern as a measure of alcoholism (author's transl)]

Authors: Berghaus, G; Kurz, A; Dotzauer, G (1975) Deutsche Medizinische Wochenschrift 100:1233-1238. HERO ID: 4943606

[Less] Samples from the right lobe of the liver and from fat tissue of the abdominal wall were removed shortly . . . [More] Samples from the right lobe of the liver and from fat tissue of the abdominal wall were removed shortly after death from 116 persons. Fatty-acid pattern of both tissues (lauric, myristic, palmitic, palmitoleic, stearic, oleic, linoleic acids) was measured and compared with the degree of fatty infiltration of the liver. The data were also correlated with chronic excess alcohol consumption in the pre-terminal phase. It was found that with increasing fatty inflitration there was a rise in the relative proportion of palmitoleic acid in liver and subcutaneous fat tissues, with a fall in the relative proportion of stearic acid in the latter. Comparison of results in alcoholics (19 subjects) and non-alcoholics (91) showed the expected higher fatty infiltration of the liver in the former (x equal 13.4% and 5.6%, respectively). Both in liver and subcutaneous fat tissues the relative proportion of palmitoleic acid was significantly higher in alcoholics. But while in these the proportion of palmitoleic acid in the liver was higher than in subcutaneous tissue, the relationship was the converse among the non-alcoholics.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Drug-biomolecule interactions: interaction of gentamicin with lipid monomolecular films

Authors: Auslander, DE; Felmeister, A; Sciarrone, BJ (1975) HERO ID: 4932668

[Less] The interaction of gentamicin with monomolecular films of a series of biologically important lipids . . . [More] The interaction of gentamicin with monomolecular films of a series of biologically important lipids spread on an aqueous buffered subphase was studied. The surface pressure, pi, of these films was determined by the Wilhelmy plate method as a function of surface area, A, and pi-A curves were constructed. Changes in the pi-A characteristics in the presence of gentamicin were used as a measure of antibiotic-film interaction. No interaction was observed between gentamicin and films of cholesterol, egg lecithin, dipalmitoyl lecithin, phosphatidyl ethanolamine, stearyl alcohol, and bovine ceramides at all pH values studied. Stearic acid films showed no interaction with gentamicin at pH 5. At pH 7 and 8, a small increase in pressure (approximately 3 dynes/cm) was noted. A dramatic increase in surface pressure was observed in the presence of stearyl aldehyde films ranging from approximately 9 dynes/cm at pH 7,2 to 23 dynes/cm at pH 8.4. This effect was attributed to a Schiff-base reaction between the nonprotonated primary amino groups on the gentamicin molecule and the stearyl aldehyde. Further evidence was reported by the fact that the addition of glucose (which has been reported to participate in Schiff-base formation with amines) to the subphase inhibited the stearyl aldehyde-gentamicin interaction. Sucrose did not show a corresponding effect. The addition of sodium bisulfite, which reacts with aldehydes to form alpha-hydroxysulfonic acid, also inhibited the gentamicin-stearyl aldehyde interaction. It is postulated that Schiff-base formation is a step in the in vivo transport of gentamicin across the membrane of sensitive organisms.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

A comparison of tar liquid and cetrimide shampoo in the management of psoriasis of the scalp

Authors: Cunliffe, WJ; Dodman, B (1974) HERO ID: 4932658


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Double-blind trial of a new topical corticosteroid in a US naval hospital

Authors: Levy, J; Highly, FM, Jr (1974) Military Medicine 139:728–730. HERO ID: 4934150

[Less] IPA COPYRIGHT: ASHP Fluocinonide, formulated at a concentration of 0.05% in FAPG base, (stearyl alcohol, . . . [More] IPA COPYRIGHT: ASHP Fluocinonide, formulated at a concentration of 0.05% in FAPG base, (stearyl alcohol, glycerine, polyethylene glycol, and propylene glycol) was evaluated in a double-blind study conducted on 56 patients with symmetrical, steroid-responsive lesions. There were 25 cases of psoriasis, 22 of atopic dermatitis, and 9 miscellaneous cases. Patients were given 2 tubes of medication at each visit, one labeled right side, the other labeled left side. The cream was applied twice daily. After the initial evaluation, patients were seen at intervals of approximately 7, 14, and 21 days. Results in all dermatoses were quite good with fluocinonide when compared with placebo. A number of patients complained of minor side effects such as burning, itching, dryness, and scaling. One patient dropped out because the lesions appeared worsened after the 1 week. Results appear to confirm the clinical efficacy of the formulation in the treatment of corticosteroid responsive dermatoses.