Health & Environmental Research Online (HERO)


Squalane (111-01-3)


134 References Were Found:

Technical Report
Technical Report

2,6,10,15,19,23-hexamethyltetracosane: skin irritation/corrosion: 003 supporting | experimental result

Author: ECHA (1995) HERO ID: 5016715


Technical Report
Technical Report

2,6,10,15,19,23-hexamethyltetracosane: acute toxicity: oral: 002 supporting | experimental result

Author: ECHA (1995) HERO ID: 5016720

[Less] Assessment of acute toxicity of squalan in rats was conduced according "guidelines for toxicity studies . . . [More] Assessment of acute toxicity of squalan in rats was conduced according "guidelines for toxicity studies issued by Ministry of Health and Welfare of Japan (MHW) - 1993. The test item was administered orally to rats (male and female) at the unique dose of 2000 mg/kg and its acute toxicity was assessed. Observation period was conduced from J0 (administration) to J14.

No deaths occurred throughout the observation period, no abnormality was observed and the body weight gain increased normally.

Based on these results, it is concluded that the oral LDL0 (lethal dose lowest) of squalan is greater than 2 000mg/kg.

Technical Report
Technical Report

2,6,10,15,19,23-hexamethyltetracosane: skin sensitisation: 003 supporting | experimental result

Author: ECHA (1994) HERO ID: 5016702


Technical Report
Technical Report

2,6,10,15,19,23-hexamethyltetracosane: skin irritation/corrosion: 004 supporting | experimental result

Author: ECHA (1994) HERO ID: 5016703


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

A CONTRIBUTION TO THE QUALITATIVE GC ANALYSIS OF SOME NON-CHLORINATED XENOBIOTIC CHEMICALS IN WASTE WATERS

Authors: Skrbic, BD; Vojinovic-Miloradov, MB (1994) Water, Science and Technology 30:91-93. HERO ID: 1485580

Abstract: BIOSIS COPYRIGHT: BIOL ABS. RRM RESEARCH ARTICLE POLLUTION GAS CHROMATOGRAPHY

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

[Stimulating effect of dietary fiber on fecal excretion of polychlorinated dibenzofurans (PCDF) and polychlorinated dibenzo-p-dioxins (PCDD) in rats]

Authors: Morita, K; Hirakawa, H; Matsueda, T; Iida, T; Tokiwa, H (1993) Fukuoka Acta Medica 84:273-281. HERO ID: 2926805

[Less] We investigated the stimulating effect of dietary fiber on fecal excretion of PCDF and PCDD stored in . . . [More] We investigated the stimulating effect of dietary fiber on fecal excretion of PCDF and PCDD stored in the rat body. Twenty-eight male rats (71-74g body weight) were orally administered with 1ml of the causal rice oil of Yusho desease. The rice oil was contaminated with 2, 3, 4, 7, 8-pentaCDF (691.4ng), 1, 2, 3, 4, 7, 8-hexaCDF (708.6ng), 1, 2, 3, 6, 7, 8-hexaCDF (128.4ng), 1, 2, 3, 7, 8-pentaCDD (7.2ng), 1, 2, 3, 6, 7, 8-hexaCDD (34.1ng), 1, 2, 3, 7, 8, 9-hexaCDD (20.1ng) and 1, 2, 3, 4, 6, 7, 8-heptaCDD (115.9ng). The animals were fed a control diet containing 10% cellulose for seven days. Twenty-eight rats consisting of four rats a group were housed and rats of each group were given a treatment diet containing 10% rice-bran-fiber (RBF), 5% cholestyramine, 10% RBF + 5% cholestyramine, 10% RBF + 5% cholestyramine + 1% squalane, 10% burdock-fiber, 10% corn-fiber and 10% soybean-fiber during a period from eight to twenty-one days. The remaining four rats served as controls. PCDF and PCDD in feces, liver, small intestine and gastrointestinal tract were analyzed by high resolution gas chromatography-mass spectrometry. PCDF level in small intestine of rats administered with RBF + cholestyramine showed a decrease of 40% over the level of control rats.(ABSTRACT TRUNCATED AT 250 WORDS)

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

MODEL EXPERIMENT ON THE PROTECTION EFFECT IN POLYMERS - RADIOLYSIS OF LIQUID SQUALANE IN THE PRESENCE AND ABSENCE OF ADDITIVES

Authors: Soebianto, YS; Katsumura, Y; Ishigure, K; Kubo, J; Koizumi, T; Shigekuni, H; Azami, K (1993) Polymer Degradation and Stability 42:29-40. HERO ID: 4972374

[Less] A model experiment to clarify the elementary processes in aliphatic polymers irradiated under vacuum . . . [More] A model experiment to clarify the elementary processes in aliphatic polymers irradiated under vacuum has been carried out. Liquid squalane has been selected as the model of branched polyethylene, ethylene-propylene copolymers or polypropylene. The main gaseous product is H-2. The presence of methyl side groups increases the probability of main chain scission, and side chain scission produces methane as the main hydrocarbon gas product. The prominence of main chain scission and the chemical structure of the parent molecule are believed to be the reasons for formation of less oligomeric products. On the other hand, they promote the combination of the scission fragment with the parent radicals to produce intermediate compounds. In the presence of aromatic additives which have a lower ionization potential and lower excited state energy level than the squalane itself, energy and charge transfer to the added molecules take place and both solvent decomposition and product formation including H-2 evolution are significantly reduced. Due to these transfer processes, the added molecules react with squalane molecules to produce adduct compounds which are clearly observed from the mass analysis. A further inspection of the mass spectra shows that scavenging of hydrogen atoms occurs through hydrogenation of the benzene rings in the adducts. Since the adduct compounds of aromatic additives consume more hydrogen atoms than those of hydroaromatic additives, aromatic compounds reduce H-2 evolution more effectively than do hydroaromatic compounds. Since main chain scission is not affected by any of the additives, it is suggested that this scission process directly originates from the decomposition of the excited cations of squalane. The G-values in the radiolysis of liquid alkanes and base polymers are also compared.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

PACKED-COLUMN SUPERCRITICAL FLUID CHROMATOGRAPHY WITH LIGHT-SCATTERING DETECTION .1. OPTIMIZATION OF PARAMETERS WITH A CARBON-DIOXIDE METHANOL MOBILE PHASE

Authors: Upnmoor, D; Brunner, G (1992) Chromatographia 33:255-260. HERO ID: 1207024

[Less] Evaporative light scattering detectors have, in recent years, gained acceptance in chromatography with . . . [More] Evaporative light scattering detectors have, in recent years, gained acceptance in chromatography with dense mobile phases i.e. liquid and supercritical fluid chromatography. In the present work an instrument of this type has been used in packed column supercritical fluid chromatography with carbon dioxide/methanol mixtures. Detector response and signal-to-noise ratios have been determined using squalane as test compound. Nebulizer gas flow, evaporator temperature, photomultiplier sensitivity, and mobile phase composition were found to have an influence on instrument performance. With this type of detector the field of packed column SFC applications can be extended to include non-UV-absorbing substances even when mixed mobile phases or composition gradients are necessary for the separation.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Study of organic pollutants in municipal wastewater in Göteborg, Sweden

Authors: Paxéus, N; Robinson, P; Balmér, P (1992) Water, Science and Technology 25:249-256. HERO ID: 667025

[Less] Influent and effluent wastewater from the Göteborg Regional Sewage Works was regularly analyzed during . . . [More] Influent and effluent wastewater from the Göteborg Regional Sewage Works was regularly analyzed during 1989-1991 for the presence of organic pollutants using GC-MS. While concentrations of individual organic compounds in the influent varied from 0.1 µg/l to several mg/l, few of them were present in the effluent in concentrations higher than 0.5 µg/l The majority of the pollutants in the influent were either food related or due to the diffuse discharge from products used both in households and in industry. For a number of priority pollutants, a declining trend in influent loadings was observed. The treatment process removes hydrophobic organic pollutants effectively. However, the effects of an increased loading of hydrophilic compounds on the treatment process need to be evaluated.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

ORGANIC GEOCHEMICAL FEATURES OF AN EXTREMELY ACID CRATER LAKE (YUGAMA) OF KUSATSU-SHIRANE VOLCANO IN JAPAN

Authors: Matsumoto, GI; Watanuki, K (1992) Geochemical Journal 26:117-136. HERO ID: 4968862

[Less] Organic geochemical study on an extremely acid crater lake (Yugama, pH = 1.2) of an active Kusatsu-Shirane . . . [More] Organic geochemical study on an extremely acid crater lake (Yugama, pH = 1.2) of an active Kusatsu-Shirane Volcano in Japan has been carried out to clarify the features and sources of organic components in relation to biological activity. Generally, n-alkanes ranging from n-C-15 to n-C36 with a predominance of long-chain (n-C20-n-C36) n-alkanes maximizing at n-C27, n-C29 or n-C31 were detected in suspended solids (greater-than-or-equal-to 0.60 mum), sulfur aggregate and surface sediments of the lake, and soils in the surroundings of the lake, together with pristane, phytane, squalane, steranes and/or triterpanes. A series of n-alkanoic acids ranging from n-C-8 to n-C32 with a predominance of even-carbon numbers were found in all the samples, along with cis- and trans-isomers of n-alkenoic acids [n-C-16:1(DELTA7 and DELTA9) and n-C18:1 (DELTA9 and DELTA11)], iso- and anteiso-alkanoic acids (C-14-C-17), and cyclopropyl alkanoic acids (C-17 and C19). No polyenoic alkenoic acids were, however, found in all the samples. Normal 3-hydroxy acids (n-C-10-nC18) mainly maximizing at n-C-14 were detected, together with iso- and anteiso-3-hydroxy acids (C-12-C18).

The features of organic components in the lake waters and sediments indicate that they can be attributed to bacteria, such as Thiobacillus thiooxidans in addition to certain uncultured bacteria, with some influences of eroded, and/or wind-transported materials containing vascular plant debris from the surroundihgs of the lake. Low concentrations of fatty acids mainly reflect the paucity of photosynthetic producers and small living biomass in the lake. Relatively high trans/cis-C-16:1 alkenoic acid ratios (0.24-0.52) may be caused by unfavorable habitat for microbial activity in the lake. The thermal maturation parameters of (20S/20R)-24-ethyl-5alpha(H), 14alpha(H), -17alpha(H)-cholestane ratios (0.49-0.77) and (22S/22R)-17alpha(H), 21,beta(H)-30-homohopane ratios (1.0-1.4) have not reached equilibrium values, but may have been significantly influenced by hydrothermal activity in the past in Lake Yugama and the surroundings of the lake.