Health & Environmental Research Online (HERO)


Trichloroethylene (TCE) (Final, 2011)

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7,935 References Were Found:

Journal Article
Journal Article

Identification and mutagenic properties of some chlorinated aliphatic compoundsin the spent liquor from kraft pulp chlorination

Authors: Kringstad, KP; Ljungquist, PO; De, SF; Stroemberg, LM HERO ID: 632689


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Potential carcinogenicity of chloral hydrate--a review

Authors: Salmon, AG; Kizer, KW; Zeise, L; Jackson, RJ; Smith, MT HERO ID: 632748

[Less] Chloral hydrate is commonly used to sedate children for diagnostic or therapeutic procedures. The drug . . . [More] Chloral hydrate is commonly used to sedate children for diagnostic or therapeutic procedures. The drug has been extensively used for many years, but there are remarkably few data on its long-term health effects. Concern in this regard is raised by recent studies showing chloral hydrate to be genotoxic, causing chromosome changes and other effects in vivo and in vitro. In addition, chloral hydrate is a reactive metabolite of trichloroethylene, a known carcinogen, and is structurally similar to other carcinogenic intermediates. Two carcinogenicity studies performed using the oral route of administration in mice indicate that the drug is potentially carcinogenic--in one case after a single dose lower than the typical dose used for sedation. Practitioners should be aware of chloral hydrate's genotoxicity and potential carcinogenicity. Discretion in its use seems appropriate until further studies clarify its long term health consequences.AYT - MISCELLANEOUS CATEGORY

Book/Book Chapter
Book/ Chapter

Dichloroacetic acid is mutagenic in big blue transgenic b6c3f1 mouse liver au - leavitt sa

Author: Ross, JA HERO ID: 629880


Journal Article
Journal Article

Nephrotoxic, mutagenic and carcinogenic potentials of dichloroacetylene and its decomposition products

Authors: Reichert, D; Spengler, U; Romen, W; Henschler, D HERO ID: 632742


Journal Article
Journal Article

The evaluation for genotoxicity of several halogenated solvents

Authors: Shimada, T; Swanson, A; Leber, P; Williams, GM HERO ID: 632756