Health & Environmental Research Online (HERO)


Trichloroacetic acid (TCA) (Final, 2011)


309 References Were Found:

Technical Report
Technical Report

Guidelines and methodology for the preparation of health effect assessment chapters of the ambient water quality criteria documents

Author: U.S. EPA (1980) HERO ID: 29154


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Identification of organic compounds in a mutagenic extract of a surface drinking water by a computerized gas chromatography/mass spectrometry system (GC/MS/COM)

Authors: Coleman, WE; Melton, RG; Kopfler, FC; Barone, KA; Aurand, TA; Jellison, MG (1980) Environmental Science and Technology 14:576-588. HERO ID: 758837

[Less] HEEP COPYRIGHT: BIOL ABS. The organics in a Cincinnati, Ohio (USA) drinking water sample were concentrated . . . [More] HEEP COPYRIGHT: BIOL ABS. The organics in a Cincinnati, Ohio (USA) drinking water sample were concentrated by a reverse osmosis (RO) process. The diethyl ether soluble extract of the RO concentrate, which was mutagenic in studies using the Ames test (using Salmonella typhimurium), was partitioned into acid and base/neutral fractions. The unpartitioned ethyl ether concentrate, an acid and methylated acid fraction, the unpartitioned base/neutral extract, and 5 base/neutral eluants from a silica gel microcolumn were analzyed for the presence of organics using a computerized gas chromatography/mass spectrometry system (GC/COM) equipped with glass capilalry columns. Analysis of individual fractions indicated a predominance of polychlorinated biphenyls (PCB) and chlorinated aromatics in the 2nd base/neutral partition and many polynuclear aromatics (PNA) in the 4th base/neutral partition. Approximately 460 compounds were identified in this tap water extract, including 41 PNA, 15 PCB and a number of amines, amides and other halogenated species. (Human applicability is discussed. Some of the water impurities may be carcinogenic)./ANATOMY and HISTOLOGY

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Mutagenicity produced by aqueous chlorination of organic compounds

Authors: Rapson, WH; Nazar, MA; Butsky, VV (1980) Bulletin of Environmental Contamination and Toxicology 24:590-596. HERO ID: 29144

[Less] HEEP COPYRIGHT: BIOL ABS. SALMONELLA-TYPHIMURIUM TA-100 AMES TEST LIGNIN ACETOVERATRONE VANILLIN KRAFT . . . [More] HEEP COPYRIGHT: BIOL ABS. SALMONELLA-TYPHIMURIUM TA-100 AMES TEST LIGNIN ACETOVERATRONE VANILLIN KRAFT PULP SYRINGALDEHYDE SOFTWOOD PULP ACETO VANILLONE 1 3 DI CHLORO ACETONE 1 1 3 3 TETRA CHLORO ACETONE 3 6 DI CHLORO-2-HYDROXY BENZALDEHYDE DI BROMO METHANE MUCO CHLORIC-ACID MUTAGEN

Book/Book Chapter
Book/ Chapter

Effects of ammonia and ammonium on tolerance and byssogenesis in Perna viridis

Authors: Reddy, NA; Menon, NR (1979) HERO ID: 8074


Book/Book Chapter
Book/ Chapter

Ionisation constants of organic acids in aqueous solution

Authors: Serjeant, EP; Dempsey, B (1979) In IUPAC chemical data series (pp. 989). Oxford: Pergamon Press. HERO ID: 759166


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Gas chromatographic determination of chloral hydrate, trichloroethanol and trichloroacetic acid in blood and in urine employing head-space analysis

Authors: Breimer, DD; Ketelaars, HCJ; Van Rossum, JM (1974) HERO ID: 62008


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Metabolism of trichloroethylene in man: II. Pharmacokinetics of metabolites

Authors: Muller, G; Spassovski, M; Henschler, D (1974) Archives of Toxicology 32:283-295. HERO ID: 58158

[Less] Trichloroethylene (Tri) metabolites, i.e. chloral hydrate (Chl), trichloroethanol (TCE) and trichloroacetic . . . [More] Trichloroethylene (Tri) metabolites, i.e. chloral hydrate (Chl), trichloroethanol (TCE) and trichloroacetic acid (TCA), were administered to volunteers to determine the pharmacokinetic activity in the blood and urine. Immediate oxidation of Chl to TCA amounting to approx. 50% was followed by slow subsequent formation of TCA persisting for 30 h. TCA was also formed from TCE over a prolonged interval. After incorporation of Tri, Chl, or TCE, identical half-lives were found for TCE (approx. 12 h), while the TCA half-lives differed greatly, being most prolonged after Tri (approx. 100 h), somewhat lowered after Chl and TCE (approx. 65 h), and shortest after TCA (50 h). The reported findings indicate storage of both Tri and TCE in the tissues from which they are slowly released. As metabolite recovery invariably accounts for less than 50% of the doses ingested, it is suggested that additional pathways of elimination must be operative, chloroform constituting only a minor portion.
During industrial operations the degree of Tri inhalation varies considerably from one hour to the next and from day to day. Due to the completely different pharmacokinetic behavior of TCE and TCA, it is not permissible to evaluate previous exposure to Tri on the basis of the urinary TCE and/or TCA excretion.

Technical Report
Technical Report

Urinary metabolites from controlled exposures of humans to trichloroethylene

Author: NIOSH (1973) HERO ID: 759188


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Trichloroethylene exposure and trichloroethylene metabolites in urine and blood

Authors: Muller, G; Spassovski, M; Henschler, D (1972) Archives of Toxicology 29:335-340. HERO ID: 75175

[Less] After trichloroethylene (Tri) inhalation the metabolite trichloroethanol (TCE) is excreted rapidly in . . . [More] After trichloroethylene (Tri) inhalation the metabolite trichloroethanol (TCE) is excreted rapidly in the urine, while trichloroacetic acid (TCA) accumulates in the organism due to a high plasma protein binding rate. After exposure of 5 volunteers to 50 ppm Tri for 6 h, 50 mgrg/ml TCA is found in the plasma at the end of the 5th exposure day, the amount of TCE present in the blood amounting to not more than 2.3 mgrg/ml. Instead of the previously used control of TCE + TCA in the urine, it is suggested to determine the metabolites in the blood by means of a gas Chromatographic micro technique which provides a reliable criterion of the preceding Tri exposure.