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Arsenic Hazard ID

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42,421 References Were Found:

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

THE HISTORY OF ORGANIC COMPOUNDS OF ARSENIC IN THE TREATMENT OF PROTOZOAN DISEASES

Author: Moore, B (1916) British Medical Journal 1:616-618. HERO ID: 1027369


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

CHEMOPATHOLOGICAL STUDIES WITH COMPOUNDS OF ARSENIC : IV. THE CHARACTER AND DISTRIBUTION OF RENAL INJURY PRODUCED BY ARSENICALS AS INDICATED BY THE PROCESSES OF REPAIR

Authors: Pearce, L; Brown, WH (1916) Journal of Experimental Medicine 23:443-459. HERO ID: 1027371

[Less] 1. The processes of repair in the kidneys of guinea pigs after sublethal doses of certain arsenical . . . [More] 1. The processes of repair in the kidneys of guinea pigs after sublethal doses of certain arsenical compounds indicate that all arsenicals do not produce a purely vascular type of renal injury. 2. While some arsenicals produce a predominantly vascular injury and others produce a predominantly tubular injury, both these tissue elements are undoubtedly always affected, although in varying proportion. In addition, the interstitial connective tissue is probably always affected. The diffuse proliferation of this tissue may be relatively conspicuous in the processes of repair after arsenicals that cause but slight vascular injury. 3. All red kidneys do not necessarily show identical pictures during the processes of repair; the same is true of pale kidneys. 4. The mode of action of an arsenical compound as a renal toxic agent is bound up with the chemical constitution of the compound.

Book/Book Chapter
Book/ Chapter

The Printing And Publishing Industry

(1916) In Kober, GM; Hanson, WC (Eds.), Diseases of occupation and vocational hygiene (pp. 609-617). Philadelphia, PA: Blakiston's Son. HERO ID: 1231272

[Less] Occupational diseases and hazards in the printing industry (SIC-2751) are reviewed. Diseases of the . . . [More] Occupational diseases and hazards in the printing industry (SIC-2751) are reviewed. Diseases of the respiratory system including tuberculosis are the chief occupational diseases of those in printing. Digestive organ diseases are also found. Type metal and type founding involve exposure to lead (7439921), arsenic (7440382), and antimony (7440360). Plumbago dust inhalation or ingestion in electrotyping predisposes to diseases of the respiratory organs, but also causes lead poisoning. The compositor is chiefly exposed to the inhalation and ingestion of the dust from the type cases. Danger from type case dust can be reduced by proper handwashing and construction of the cases. The operators in monotyping and linotyping are exposed to irritating acrolein (107028) vapors from fluxing metal. Suitable hoods and exhaust flues connected to the melting pots can obviate the problem. Molten metal in stereotyping involves handling of lead and exposure to its toxic effects. Electrotyping exposes workers to irritating fumes. Workers engaged in melting new metal and old slugs are exposed to the risk of plumbism from handling metal and breathing its toxic fumes. Binding room exposures to dust, heat, and wood alcohol (67561) are injurious. Workers in chromolithography are in danger of lead poisoning. Many also suffer from visual defects. Engravers have considerable eye strain. Photoengravers are exposed to gas fumes, acids, and ammonium-dichromate (7789095). Metal etchers are exposed to chromic-acid (13530682) causing chrome ulcers. Workers in photographic facilities are exposed to contaminated air and light and to industrial poisons such as bromine (7726956). Other conditions found are bronchial irritation, erythematous rash, and eczema. The author concludes that hazards to the respiratory organs can be reduced by use of sanitary and hygenic procedures and suitable exhaust and ventilation.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

CHEMOPATHOLOGICAL STUDIES WITH COMPOUNDS OF ARSENIC : III. ON THE PATHOLOGICAL ACTION OF ARSENICALS ON THE ADRENALS

Authors: Brown, WH; Pearce, L (1915) Journal of Experimental Medicine 22:535-543. HERO ID: 1027372

[Less] 1. Toxic doses of all arsenicals of which we have any knowledge produce definite pathological changes . . . [More] 1. Toxic doses of all arsenicals of which we have any knowledge produce definite pathological changes in the adrenals of guinea pigs. These changes include congestion, hemorrhage, disturbances in the lipoid content, cellular degenerations and necroses, and reduction in the chromaffin content. 2. The character and severity of the injury produced by different arsenicals varies with the chemical constitution of the compounds. 3. From these facts, we believe that adrenal injury is an important factor in arsenical intoxication and suggest that therapeutic doses of some arsenicals may produce adrenal stimulation.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

CHEMOPATHOLOGICAL STUDIES WITH COMPOUNDS OF ARSENIC : II. HISTOLOGICAL CHANGES IN ARSENIC KIDNEYS

Authors: Pearce, L; Brown, WH (1915) Journal of Experimental Medicine 22:525-534. HERO ID: 1027374

[Less] 1. We have shown that the type of renal lesion produced by compounds of arsenic varies widely: while . . . [More] 1. We have shown that the type of renal lesion produced by compounds of arsenic varies widely: while some arsenicals produce changes in which vascular injury predominates, others produce an equally dominant tubular injury. 2. In either of these groups the character and degree of the vascular or tubular injury produced by different compounds shows further variation, such that the lesions of different arsenicals of the same group are not identical. Each compound of arsenic that we have tested, therefore, produces a lesion-complex in the kidney that is relatively characteristic for that compound. 3. The mode and character of the action of arsenicals are dependent upon the chemical constitution of the compound.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

CHEMOPATHOLOGICAL STUDIES WITH COMPOUNDS OF ARSENIC : I. TYPES OF THE ARSENIC KIDNEY

Authors: Pearce, L; Brown, WH (1915) Journal of Experimental Medicine 22:517-524. HERO ID: 1027375

[Less] 1. All arsenical compounds do not produce the same type of renal injury. 2. In general, there are two . . . [More] 1. All arsenical compounds do not produce the same type of renal injury. 2. In general, there are two broad groups of kidneys produced, the red and the pale, with a variety of subdivisions of each group depending upon modifications in the chemical constitution of the compound, dosage, and length of survival of the animal.

Journal Article
Journal Article

Preliminary Report on the Finding of Arsenic in the Cerebrospinal Fluid following Intravenous Administration of Neosalvarsan

Author: Barbat, JH (1915) 13:438. HERO ID: 1027376


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Variations in the Character and Distribution of the Renal Lesions Produced by Compounds of Arsenic

Authors: Pearce, L; Brown, WH (1915) Proceedings of the National Academy of Sciences 1:463-464. HERO ID: 1027378


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

THE EFFECT OF ARSENIC COMPOUNDS ON THE ROUS CHICKEN SARCOMA

Author: Funk, C (1915) Journal of Experimental Medicine 21:574-575. HERO ID: 1027380

[Less] Arsenic and arsenious acids, cacodylic acid, atoxyl, and neosalvarsan fail to influence markedly the . . . [More] Arsenic and arsenious acids, cacodylic acid, atoxyl, and neosalvarsan fail to influence markedly the growth of the Rous chicken sarcoma.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

A FURTHER STUDY OF NITROGEN RETENTION IN THE BLOOD IN EXPERIMENTAL ACUTE NEPHRITIS

Authors: Karsner, HT; Denis, W (1914) Journal of Experimental Medicine 19:259-269. HERO ID: 1027382

[Less] These studies, like all studies of the kidney, are difficult of interpretation because of the impossibility . . . [More] These studies, like all studies of the kidney, are difficult of interpretation because of the impossibility of producing a pure glomerular or pure tubular nephritis. Arsenic nephritis in its early stage is physiologically a vascular nephritis, but anatomically tubular, and shows in this stage almost no retention of nitrogen, although studies of urinary nitrogen indicate an increased catabolism. On the other hand, diphtheria nephritis in the early stages is anatomically a nephritis with marked involvement of the glomerulus anatomically, but it is physiologically a tubular form, and in this early stage there is little or no nitrogen retention although studies of metabolism indicate that protein catabolism is increased by the administration of diphtheria toxin. In both cases, however, there appears to come a time when the excreting power of the kidney is exhausted and nitrogen accumulation occurs in the blood. This is much less marked in the arsenic nephritis, with less tubular change, than in diphtheria toxin nephritis with its marked tubular degeneration. This same late accumulation of blood nitrogen is seen in immune serum nephritis, where the tubular changes are persistent and relatively more severe than the glomerular change. It might well be said that this is no argument for the influence of the tubules in the excretion of waste nitrogen because of the general exhaustion of the organism as a whole and of the kidney in particular, and that no positive conclusions can be drawn is indicated by the opening sentence of this summary. Tartrate nephritis was at first considered as purely tubular; but the appearance of occasional glomerular change, as mentioned by Wells in one of his animals, and the fact that the presence of precipitated albumen in the subcapsular space, pointed out by Pearce and Ringer, probably indicates an increased permeability of the tuft capillaries, all lead to the conclusion that although the tubular change predominates, there is, possibly, slight alteration of the glomerulus. This form of nephritis shows the most marked retention of nitrogen, persisting even though the glomeruli show almost no change, tending to clear up with the progress of time and evidently also with the repair of the tubular change, and bearing a direct relation to the dose of tartaric acid and presumably with the degree of tubular change. It must be remembered, however, that the nephritis in the cases of greatest retention is a very severe form, and this again clouds the physiological interpretation of the results. The study shows no reason for altering the conclusions of our earlier studies, but from the interpretation accorded above it appears to throw more stress on tubular change as determining nitrogen retention. It confirms in addition the value of the methods used for studies of this type.