Health & Environmental Research Online (HERO)


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1,526 References Were Found:

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Childhood obesity patterns and relation to middle-age sleep apnoea risk: The Bogalusa Heart Study

Authors: Bazzano, LA; Hu, T; Bertisch, SM; Yao, L; Harville, EW; Gustat, J; Chen, W; Webber, LS; Shu, T; Redline, S (In Press) . HERO ID: 3361355

[Less] BACKGROUND: Obese adults have a higher risk of obstructive sleep apnoea (OSA); however, . . . [More] BACKGROUND: Obese adults have a higher risk of obstructive sleep apnoea (OSA); however, the relationship between childhood obesity and adult OSA risk is unclear. Objectives This study aimed to examine overweight/obesity (OW) in childhood and risk of OSA in middle age.

METHODS: Childhood OW status was classified as never OW, weight cycling, persistent OW and incident OW. After 35 years of follow-up, high risk for OSA was determined by a positive score in ≥2 domains on the Berlin Questionnaire with obesity removed from scoring.

RESULTS: At initial assessment, mean (SD) age was 9.9 (2.9) years, and 23.9% were OW. Overall, 25.7% had scores indicating a high risk for OSA. Compared with participants who were never OW, those with persistent OW and incident OW were 1.36 (95%CI: 1.04-1.77) and 1.47 (1.11-1.96) times more likely to be high risk for OSA, after adjustment for multiple risk factors and adult OW status. Participants with an OW duration of 1-4 years, 5-8 years, and 8+ years were 0.96 (0.44-2.09), 1.20 (0.70-2.04) and 1.52 (1.22-1.90) times more likely to be high risk for OSA compared with those who were never OW (P for trend: 0.0002).

CONCLUSIONS: These results suggest that childhood OW is associated with a high risk of OSA in middle age.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Space-based detection of missing sulfur dioxide sources of global air pollution

Authors: McLinden, CA; Fioletov, V; Shephard, MW; Krotkov, N; Li, C; Martin, RV; Moran, MD; Joiner, J (In Press) Nature Geoscience. HERO ID: 3228432

[Less] Sulfur dioxide is designated a criteria air contaminant (or equivalent) by virtually all developed nations. . . . [More] Sulfur dioxide is designated a criteria air contaminant (or equivalent) by virtually all developed nations. When released into the atmosphere, sulfur dioxide forms sulfuric acid and fine particulate matter, secondary pollutants1 that have significant adverse effects on human health2, 3, 4, 5, the environment1 and the economy5. The conventional, bottom-up emissions inventories used to assess impacts, however, are often incomplete or outdated, particularly for developing nations that lack comprehensive emission reporting requirements and infrastructure. Here we present a satellite-based, global emission inventory for SO2 that is derived through a simultaneous detection, mapping and emission-quantifying procedure, and thereby independent of conventional information sources. We find that of the 500 or so large sources in our inventory, nearly 40 are not captured in leading conventional inventories. These missing sources are scattered throughout the developing world—over a third are clustered around the Persian Gulf—and add up to 7 to 14 Tg of SO2 yr−1, or roughly 6–12% of the global anthropogenic source. Our estimates of national total emissions are generally in line with conventional numbers, but for some regions, and for SO2 emissions from volcanoes, discrepancies can be as large as a factor of three or more. We anticipate that our inventory will help eliminate gaps in bottom-up inventories, independent of geopolitical borders and source types.

Archival Material
Archival Material

The panel study of income dynamics

Author: University of Michigan (2016) HERO ID: 3350568


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Acute impact of hourly ambient air pollution on preterm birth

Authors: Li, S; Guo, Y; Williams, G (2016) Environmental Health Perspectives 124:1623-1629. HERO ID: 3223998

[Less] BACKGROUND: Preterm birth is a major perinatal health problem but factors leading to . . . [More] BACKGROUND: Preterm birth is a major perinatal health problem but factors leading to it are still not completely understood.

OBJECTIVES: To identify the relation between acute increase in ambient air pollution in a few hours before onset of labour and the risk of preterm birth.

METHODS: We collected registered birth outcome data and hourly ambient air pollution measurements during 2009 ‒ 2013 in Brisbane, Australia. Using the time-stratified case-crossover design and conditional logistic regression models with natural cubic splines, we assessed the shape of air pollution ‒ preterm birth curve, after controlling for potential confounders. We also examined the effect modification of other factors.

RESULTS: The association between air pollution [nitrogen dioxide (NO2), sulphur dioxide (SO2), and carbon monoxide (CO)] and preterm birth was non-linear. Threshold concentrations for the mean of 0 ‒ 24 hours NO2, 24 ‒ 48 hours SO2, and 24 ‒ 48 hours CO before onset of labour were 7.6 parts per billion (ppb), 3.8 ppb, and 162.5 ppb, respectively. Increases in air pollution concentrations above thresholds were associated with increased risks of preterm birth. The ORs of preterm birth at 95th percentile of NO2, SO2 and CO against the thresholds were 1.17 (1.08, 1.27), 1.01 (0.99, 1.04), and 1.18 (1.06, 1.32), respectively. The associations were modified by demographic factors, for example, maternal smoking and socioeconomic status (SES).

CONCLUSION: Acute increases in ambient air pollution concentrations above certain levels before onset of labour may stimulate preterm birth.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Air Pollution and the Risk of Birth Defects in Anqing City, China

Authors: Yao, C; Chen, Y; Zhu, X; Liu, Y; Zhang, J; Hou, L; Xu, Y; Zhang, C; Cao, J (2016) Journal of Occupational and Environmental Medicine 58:e124-e127. HERO ID: 3224051

[Less] OBJECTIVE: This study aimed to explore evidence for the influence of air pollution . . . [More] OBJECTIVE: This study aimed to explore evidence for the influence of air pollution on the risk of birth defects in China and contribute to establish prevention strategies.

METHODS: We conducted a retrospective cohort study in Anqing city, Eastern China, from 2010 to 2012. Binary logistic regression models were used to estimate odds ratios (ORs) per 10 μg/m3 change for SO2, NO2, and PM10.

RESULTS: For continuous exposure to SO2 (10 μg/m increase), the adjusted OR for birth defects is 1.20 [95% confidence interval (95% CI) 1.09 to 1.29] in the preconception. A 10 μg/m increase in SO2 (adjusted OR 1.26, 95% CI 1.15 to 1.36) during the second trimester is strongly associated with birth defects. No associations have been observed for NO2 and PM10.

CONCLUSION: The results suggested that exposure to ambient SO2 during pregnancy may increase the risk of birth defects.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

The vasodilatory effect of sulfur dioxide via sGC/cGMP/PKG pathway in association with sulfhydryl-dependent dimerization

Authors: Yao, Q; Huang, Y; Liu, AD; Zhu, M; Liu, J; Yan, H; Zhang, Q; Geng, B; Gao, Y; Du, S; Huang, P; Tang, C; Du, J; Jin, H (2016) American Journal of Physiology: Regulatory, Integrative and Comparative Physiology 310:ajpregu.00101.2015. HERO ID: 3224083

[Less] The present study was designed to explore the role of soluble guanylate cyclase (sGC)/cyclic guanosine . . . [More] The present study was designed to explore the role of soluble guanylate cyclase (sGC)/cyclic guanosine monophosphate (cGMP)/protein kinase G (PKG) pathway in sulfur dioxide (SO2)-induced vasodilation. We showed that SO2induced a concentration-dependent relaxation of phenylephrine (PE)-precontracted rat aortic rings in association with an increase in cGMP concentration, whereas L-aspartic acid β-hydroxamate (HDX), an inhibitor of SO2synthase, contracted rings in a dose-dependent manner. Pretreatment of aortic rings with the sGC inhibitor ODQ (30 μM) attenuated the vasodilatory effects of SO2, suggesting the involvement of cGMP pathway in SO2-induced vasodilation. Mechanistically, SO2upregulated the protein levels of sGC and PKG dimers, while HDX inhibited it, indicating SO2could promote cGMP synthesis through sGC activation. Furthermore, the dimerization of sGC and PKG and vasodilation induced by SO2in precontracted rings were significantly prevented by thiol reductants dithiothreitol (DTT). In addition, SO2reduced the activity of phosphodiesterase type 5 (PDE5), a cGMP-specific hydrolytic enzyme, implying that SO2elevated cGMP concentration by inhibiting its hydrolysis. Hence, SO2exerted its vasodilatory effects at least partly by promoting disulfide-dependent dimerization of sGC and PKG, resulting in an activated sGC/cGMP/PKG pathway in blood vessels. These findings revealed a new mode of action and mechanisms by which SO2regulated the vascular tone.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Sulfur dioxide contributes to the cardiac and mitochondrial dysfunction in rats

Authors: Qin, G; Wu, M; Wang, J; Xu, Z; Xia, J; Sang, N (2016) Toxicological Sciences 151:334-346. HERO ID: 3224103

[Less] Epidemiological studies have demonstrated an association between sulfur dioxide (SO2) and an increase . . . [More] Epidemiological studies have demonstrated an association between sulfur dioxide (SO2) and an increase of morbidity and mortality of cardiovascular diseases, such as ischemic heart disease, heart failure, and arrhythmia. Mitochondrion is the most sensitive organelle in myocardium of animals exposed to SO2 Here we study the molecular characterization of mitochondrial dysfunction in cardiac muscles of rat after SO2exposure. We found that the cytochrome c oxidase (COX) activity, mitochondrial membrane potential (ΔΨm), ATP contents, mitochondrial DNA (mtDNA) contents, and mRNA expression of complexes IV and V subunits encoded by mtDNA were decreased after NaHSO3treatmentin vitroor SO2inhalationin vivo The mitochondrial dysfunctions were accompanied by depressions of co-activator of peroxisome proliferator activated receptor gamma (PGC-1α), nuclear respiratory factor 1, and mitochondrial transcription factor A (TFAM) mRNA and protein. We observed swollen mitochondria and lower amounts of cristae in hearts of rats after 3.5 mg/m(3)SO2inhalation for 30 days. Interestingly, NaHSO3induced mitochondrial dysfunctions marked by ΔΨm and ATP reduction could be inhibited by an antioxidant N-acetyl-L-cysteine (NALC), accompanied by the restoration of transcriptional factors expressions. The cardiac mitochondrial dysfunctions could also be alleviated by overexpression of TFAM. SO2induced abnormal left ventricular function was restored by NALC in vivo Our findings demonstrate that SO2induces cardiac and mitochondrial dysfunction. And inhibition of reactive oxygen species and enhancing the transcriptional network controlling mitochondrial biogenesis can mitigate the SO2-induced mitochondrial dysfunction.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

An increased prevalence of self-reported allergic rhinitis in major Chinese cities from 2005 to 2011

Authors: Wang, X; Zheng, M; Lou, H; Wang, C; Zhang, Y; Bo, M; Ge, S; Zhang, N; Zhang, L; Bachert, C (2016) Allergy 71:1170-1180. HERO ID: 3224117

[Less] BACKGROUND: The prevalence of allergic rhinitis (AR) has increased worldwide in recent . . . [More] BACKGROUND: The prevalence of allergic rhinitis (AR) has increased worldwide in recent decades. The present study was conducted to investigate the prevalence of self-reported AR and profiles of AR-related comorbidities in the adult population of China over time.

METHODS: This study surveyed residents of 18 major cities in mainland China. Telephone interviews were conducted with study participants after sampling target telephone numbers by random digital dialing. The questions asked during telephone interviews were based on those included in validated questionnaires, and focused on topics regarding allergic rhinitis, non-allergic rhinitis, acute/chronic rhinosinusitis, asthma, and atopic dermatitis.

RESULTS: During 2011, a total of 47,216 telephone interviews were conducted, and the overall response rate was 77.5%. When compared with the AR prevalence in 11 cities surveyed in 2005, there was a significant increase in self-reported adult AR in eight of those cities (P < 0.01). In 2011, the standardized prevalence of self-reported adult AR in the 18 cities was 17.6%. The concentration of SO2 was positively correlated with the prevalence of AR (r = 0.504, P = 0.033). A multiple regression model showed that the absolute change in household yearly income was significantly associated with the change in prevalence of AR (R(2) = 0.68), after adjusting for PM10 , SO2 , NO2, temperature and humidity. The overall prevalences of NAR, ARS, CRS, asthma, and AD in the general population were 16.4%, 5.4%, 2.1%, 5.8%, and 14%, respectively.

CONCLUSION: During a 6-year period, there was a significant increase in the prevalence of self-reported AR in the general Chinese adult population. The incidence of AR being accompanied by rhinosinusitis, asthma or AD was significantly higher among individuals having self-reported AR compared with the general population. This article is protected by copyright. All rights reserved.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Acute impact of hourly ambient air pollution on preterm birth - Supplementary material

Authors: Li, S; Guo, Y; Williams, G (2016) Environmental Health Perspectives 124. [Supplemental Data] HERO ID: 3449404


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Associations of cough prevalence with ambient polycyclic aromatic hydrocarbons, nitrogen and sulphur dioxide: A longitudinal study - Supplementary material

Authors: Anyenda, EO; Higashi, T; Kambayashi, Y; Nguyen, TT; Michigami, Y; Fujimura, M; Hara, J; Tsujiguchi, H; Kitaoka, M; Asakura, H; Hori, D; Yamada, Y; Hayashi, K; Hayakawa, K; Nakamura, H (2016) International Journal of Environmental Research and Public Health 13. [Supplemental Data] HERO ID: 3449401