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Methanol (Non-Cancer)

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8,110 References Were Found:

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Controlling Size, Amount, and Crystalline Structure of Nanoparticles Deposited on Graphenes for Highly Efficient Energy Conversion and Storage

Authors: Choi, BG; Park, HS (In Press) ChemSusChem. HERO ID: 1037655

[Less] A facilitated electrochemical reaction at the surface of electrodes is crucial for highly efficient . . . [More] A facilitated electrochemical reaction at the surface of electrodes is crucial for highly efficient energy conversion and storage. Herein, various nanoparticles (NPs) including Au, Pt, Pd, Ru, and RuO(2) , were synthesized in situ and directly deposited on the ionic liquid (IL)-functionalized reduced graphene oxides (RGOs) in a controlled manner. The size, amount, and crystalline structures of discrete NPs were readily controlled, giving rise to enhanced methanol oxidation and pseudocapacitance. The well-defined nanostructure of decorated NPs and the favorable interaction between ILs and RGOs (or NPs) facilitated the electrochemical reaction, where NPs acted as electrocatalysts for energy conversion and played the role of redox-active electrodes for energy storage.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Electronic Modulation of a Copper/Zinc Oxide Catalyst by a Heterojunction for Selective Hydrogenation of Carbon Dioxide to Methanol

Authors: Liao, F; Zeng, Z; Eley, C; Lu, Q; Hong, X; Tsang, SC (In Press) Angewandte Chemie (International Edition). HERO ID: 1037709

[Less] Methanol from CO(2) : For the hydrogenation of carbon dioxide a marked increase in the methanol selectivity . . . [More] Methanol from CO(2) : For the hydrogenation of carbon dioxide a marked increase in the methanol selectivity was observed when the reaction was catalyzed by Cu/rod-shaped ZnO/CdSe with heterojunction structure. Diffusion reflectance, photoluminescence, and ESR spectroscopies clearly indicated an increase in the electron density because of the incorporation of CdSe in the core-shell morphology of Cu/rod-shaped ZnO.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Observation of Methanol Behavior in Fuel Cells In Situ by NMR Spectroscopy

Authors: Han, OH; Han, KS; Shin, CW; Lee, J; Kim, SS; Um, MS; Joh, HI; Kim, SK; Ha, HY (In Press) Angewandte Chemie (International Edition). HERO ID: 1037739

[Less] The chemical conversion of methanol in direct methanol fuel cells was followed in situ by NMR spectroscopy. . . . [More] The chemical conversion of methanol in direct methanol fuel cells was followed in situ by NMR spectroscopy. Comparing data of the methanol oxidation on Pt and PtRu anode catalysts allowed the role of Ru in both Faradaic and non-Faradaic reactions to be investigated. The spatial distributions of chemicals could also be determined. (Picture: T1-T4=inlet and outlet tubes.).

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Radical-mediated nitrile translocation as the key step in the stereoselective transformation of 2-(4-chloro-2-cyanobutyl)aziridines to methyl cis-(1-arylmethyl-4-phenylpiperidin-2-yl)acetates

Authors: Vervisch, K; D'hooghe, M; Törnroos, KW; De Kimpe, N (In Press) Organic and Biomolecular Chemistry. HERO ID: 1037740

[Less] Non-activated 2-(4-chloro-2-cyano-2-phenylbutyl)aziridines were used as building blocks for the stereoselective . . . [More] Non-activated 2-(4-chloro-2-cyano-2-phenylbutyl)aziridines were used as building blocks for the stereoselective synthesis of novel cis-2-cyanomethyl-4-phenylpiperidines via a microwave-assisted aziridine to piperidine ring expansion followed by a radical-induced nitrile translocation through initial formation and subsequent cleavage of intermediate bicyclic iminyl radicals. Furthermore, these 2-(cyanomethyl)piperidines were shown to be eligible substrates for the preparation of methyl cis-(1-arylmethyl-4-piperidin-2-yl)acetates through a Pinner reaction using gaseous HCl in methanol.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Photo-degradation products of pramipexole

Authors: Nishimura, E; Kugimiya, A; Naoki, H; Hamanaka, N (In Press) Bioorganic and Medicinal Chemistry Letters. HERO ID: 1037692

[Less] Two pyrrolidine compounds (1 and 2) were isolated from photo-degradation of Bi-Sifrol tablets. Compound . . . [More] Two pyrrolidine compounds (1 and 2) were isolated from photo-degradation of Bi-Sifrol tablets. Compound 1 was esterified to p-bromophenacyl ester as single-crystal, and then the structure was elucidated by single-crystal X-ray study. Compound 2 was determined by 2D NMR and mass spectra. Otherwise, we established that the photo-degradation of pramipexole was smoothly carried out in the methanol solution, and elucidate the degradation mechanism.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Stabilization of High-Valence Ruthenium with Silicotungstate Ligands: Preparation, Structural Characterization, and Redox Studies of Ruthenium(III)-Substituted α-Keggin-Type Silicotungstates with Pyridine Ligands, [SiW(11) O(39) Ru(III) (Py)](5-)

Authors: Sadakane, M; Moroi, S; Iimuro, Y; Izarova, N; Kortz, U; Hayakawa, S; Kato, K; Ogo, S; Ide, Y; Ueda, W; Sano, T (In Press) Chemistry - An Asian Journal. HERO ID: 1038308

[Less] Ruthenium(III)-substituted α-Keggin-type silicotungstates with pyridine-based ligands, [SiW(11) O(39) . . . [More] Ruthenium(III)-substituted α-Keggin-type silicotungstates with pyridine-based ligands, [SiW(11) O(39) Ru(III) (Py)](5-) , (Py: pyridine (1), 4-pyridine-carboxylic acid (2), 4,4'-bipyridine (3), 4-pyridine-acetamide (4), and 4-pyridine-methanol (5)) were prepared by reacting [SiW(11) O(39) Ru(III) (H(2) O)](5-) with the pyridine derivatives in water at 80 °C and then isolated as their hydrated cesium salts. These compounds were characterized using cyclic voltammetry (CV), UV/Vis, IR, and (1) H NMR spectroscopy, elemental analysis, titration, and X-ray absorption near-edge structure (XANES) analysis (Ru K-edge and L(3) -edge). Single-crystal X-ray analysis of compounds 2, 3, and 4 revealed that Ru(III) was incorporated in the α-Keggin framework and was coordinated by pyridine derivatives through a RuN bond. In the solid state, compounds 2 and 3 formed a dimer through ππ interaction of the pyridine moieties, whereas they existed as monomers in solution. CV indicated that the incorporated Ru(III) -Py was reversibly oxidized into the Ru(IV) -Py derivative and reduced into the Ru(II) -Py derivative.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Application of High-speed Countercurrent Chromatography-Evaporative Light Scattering Detection for the Separation of Seven Steroidal Saponins from Dioscorea villosa

Authors: Yoon, KD; Chin, YW; Yang, MH; Choi, J; Kim, J (In Press) Phytochemical Analysis. HERO ID: 1037843

[Less] INTRODUCTION: Steroidal saponins in Dioscorea species are chemically characterised as spirostanol and . . . [More] INTRODUCTION: Steroidal saponins in Dioscorea species are chemically characterised as spirostanol and furostanol saponins, and have been used as standard marker compounds due to their chemotaxonomical significance and their important biological activities. OBJECTIVE: To design a simple, rapid and efficient method for the separation of steroidal saponins with a high degree of purity using high-speed countercurrent chromatography (HSCCC) coupled with evaporative light scattering detection (ELSD). METHODOLOGY: In the first step, reversed-phase mode HSCCC (flow rate: 1.5 mL/min; revolution speed: 800 rpm) using n-hexane:n-butanol:water [3:7:10 (v/v/v)] was employed to separate furostanol saponins from n-butanol soluble extracts of Dioscorea villosa. After the first HSCCC run, spirostanol saponins retained in the stationary phase were subjected to the second HSCCC (normal-phase mode; flow rate: 2.0 mL/min; revolution speed: 800 rpm). A two-phase solvent system composed of chloroform:methanol:isopropanol:water [10:6:1:4 (v/v/v/v)] was employed in the second HSCCC. The structures of isolates were elucidated by (1) H-NMR, (13)  C-NMR, ESI-MS and HPLC analysis. RESULTS: Three furostanol saponins, parvifloside (27.3 mg), methyl protodeltonin (67.1 mg) and trigofoenoside A-1 (18.5 mg) were isolated from the n-butanol soluble extract of D. villosa by the first HSCCC run. Subsquent normal-phase HSCCC of the spirostanol-rich extract led to the separation of four spirostanol saponins: zingiberensis saponin I (15.2 mg), deltonin (31.5 mg), dioscin (7.7 mg) and prosapogenin A of dioscin (3.4 mg). Copyright © 2012 John Wiley & Sons, Ltd.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Simultaneous determination of tyrosine, tryptophan and 5-hydroxytryptamine in serum of MDD patients by high performance liquid chromatography with fluorescence detection

Authors: Sa, M; Ying, L; Tang, AG; Xiao, LD; Ren, YP (In Press) . HERO ID: 1037853

[Less] BACKGROUND: Tyrosine (Tyr), Tryptophan (Trp) and 5-hydroxytryptamine (5-HT) are important amino acids . . . [More] BACKGROUND: Tyrosine (Tyr), Tryptophan (Trp) and 5-hydroxytryptamine (5-HT) are important amino acids in vivo and have been hypothesized to be involved in many mental disorders. We developed a rapid and sensitive HPLC method for simultaneous measurement of serum Tyr, Trp and 5-HT and explored the clinical significances of Tyr, Trp and 5-HT and the 5-HT/Trp ratio for patients with major depressive disorder (MDD) disease. METHODS: Serum samples were deproteinized by 5% perchloric acid and separated on an Atlantis C18 column (4.6×150mm, 5μm) with the mobile phase consisting of 0.1mol/l KH(2)PO(4) and methanol (85:15, V/V).The eluates were monitored by the fluorescence detection with programmed wavelength. RESULTS: Analysis was achieved in <12.0min. The limits of quantification were 0.014, 0.005, and 0.024μmol/l for Tyr, Trp and 5-HT, respectively. Reproducibility and recovery were satisfactory. Tyr, Trp and 5-HT and the 5-HT/Trp ratio were significantly decreased in patients with MDD. CONCLUSIONS: In diseases, like MDD, Tyr, Trp and 5-HT play an important role. This method can potentially be applied as prognostic or diagnostic tool or even to follow the evolution of the illness or of the treatment.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Synthesis and Evaluation of (2-(4-Methoxyphenyl)-4-quinolinyl)(2-piperidinyl)methanol (NSC23925) Isomers To Reverse Multidrug Resistance in Cancer

Authors: Duan, Z; Li, X; Huang, H; Yuan, W; Zheng, SL; Liu, X; Zhang, Z; Choy, E; Harmon, D; Mankin, H; Hornicek, F (In Press) Journal of Medicinal Chemistry. HERO ID: 1037859

[Less] Development of multidrug resistance (MDR) during chemotherapy is a fundamental obstacle associated with . . . [More] Development of multidrug resistance (MDR) during chemotherapy is a fundamental obstacle associated with cancer care. Prior studies have identified (2-(4-methoxyphenyl)-4-quinolinyl)(2-piperidinyl)methanol (5) (NSC23925) to be a small molecule agent that reverses MDR in cancer cells. We synthesized all four isomers of 5 and analyzed them by liquid chromatography-mass spectrometry (LCMS). Structure-activity relationships for reversing MDR were evaluated. Isomer 11 demonstrated the most potent activity. 11 reversed MDR in several drug-resistant cell lines expressing Pgp, including ovarian, breast, colon, uterine, and sarcoma cancer. 11 resensitized these cell lines to paclitaxel, doxorubicin, mitoxantrone, vincristine, and trabectedin with no effect on cell sensitivity to cisplatin, topotecan, and methotrexate. 11 significantly enhanced in vivo antitumor activity of paclitaxel in MDR xenograft models, without increasing the level of paclitaxel toxicity. In conclusion, 11 and derivatives of this compound may hold therapeutic value in the treatment of MDR-dependent cancers.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Antimicrobial activity of sesquiterpene lactones isolated from traditional medicinal plant, Costus speciosus (Koen ex.Retz.) Sm

Authors: Duraipandiyan, V; Al-Harbi, NA; Ignacimuthu, S; Muthukumar, C (In Press) BMC Complementary and Alternative Medicine. HERO ID: 1037869

[Less] ABSTRACT: BACKGROUND: Costus speciosus (Koen ex.Retz.) Sm (Costaceae) is an Indian ornamental plant . . . [More] ABSTRACT: BACKGROUND: Costus speciosus (Koen ex.Retz.) Sm (Costaceae) is an Indian ornamental plant which has long been used medicinally in traditional systems of medicine. The plant has been found to possess diverse pharmacological activities. Rhizomes are used to treat pneumonia, rheumatism, dropsy, urinary diseases, jaundice, skin diseases and leaves are used to treat mental disorders. METHOD: Antibacterial and antifungal activities were tested using Disc diffusion method and Minimum Inhibitory Concentration (MIC). Column chromatography was used to isolate compounds from hexane extract. X-ray crystallography technique and GC-MS analysis were used to identify the compounds RESULTS: Antibacterial and antifungal activities were observed in hexane, chloroform, ethyl acetate and methanol extracts. Hexane extract of C.speciosus showed good activity against tested fungi also. Two sesquiterpenoid compounds were isolated (costunolide and eremanthin) from the hexane extract. Both the compounds did not inhibit the growth of tested bacteria. But, both the compounds inhibited the tested fungi. The compound costunolide showed significant antifungal activity. The MIC values of costunolide were; 62.5 mug/ml against Trichophyton mentagrophytes, 62. mug/ml against T. simii, 31.25 mug/ml against T. rubrum 296, 62.5 mug/ml against T. rubrum 57, 125 mug/ml against Epidermophyton floccosum, 250 mug/ml against Scopulariopsis sp, 250 mug/ml against Aspergillus niger, 125 mug/ml against Curvulari lunata, 250 mug/ml against Magnaporthe grisea. CONCLUSION: Hexane extract showed promising antibacterial and antifungal activity. The isolated compound costunolide showed good antifungal activity.