Health & Environmental Research Online (HERO)


Chromium VI

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326 References Were Found:

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Reply to: Pesch B, Weiss T, Pallapies D, Schlüter G, Brüning T. Letter to the editor. Re: Seidler A, Jähnichen S, Hegewald J, Fishta A, Krug O, Rüter L, Strik C, Hallier E, Straube S. Systematic review and quantification of respiratory cancer risk for occupational exposure to hexavalent chromium

Authors: Seidler, A; Jähnichen, S; Hegewald, J; Fishta, A; Krug, O; Rüter, L; Strik, C; Hallier, E; Straube, S (In Press) International Archives of Occupational and Environmental Health. [Letter] HERO ID: 1786253


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

WITHDRAWN: Hexavalent chromium induces premature senescence through reactive oxygen species-mediated p53 pathway in L-02 hepatocytes

Authors: Xiao, F; Hu, Q; Zeng, M; Guan, L; Liu, X; Yang, Y; Zhong, C (In Press) HERO ID: 1509895

[Less] This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes . . . [More] This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy.

Journal Article
Journal Article

Health Hazard Evaluation Report No. HETA-90-174-2231, Modern Materials Incorporated, Rochester, Indiana

Authors: Mouradian, RF; Deitchman, S (2231) HERO ID: 1516187

[Less] In response to a request from the management of Modern Materials Incorporated (SIC-3479), Rochester, . . . [More] In response to a request from the management of Modern Materials Incorporated (SIC-3479), Rochester, Indiana, possible chemical exposures associated with powder coating operations, specifically isocyanates used in some powder coatings, were evaluated. Air sampling indicated that the concentrations of most of the targeted chemicals were well below the Permissible Exposure Limits (PELs) and Recommended Exposure Limits (RELs). However, some exposures to epsilon-caprolactam (105602), formaldehyde (50000), and sulfur-dioxide (7446095) exceeded these limits. Conditions were observed which allowed dermal exposure to corrosives to occur, including hexavalent chromium (7440473). Inoperative eye washes, inadequate personal protective equipment, and apparent failure to meet communications requirements were also noted. The authors conclude that employees were exposed to potentially hazardous concentrations of aldehydes, epsilon-caprolactam, and sulfur-dioxide, and that there was a potential for hazardous exposures to other materials, and to unsafe conditions from inadequate use of safety devices and personal protective equipment. It was not possible to determine if workers had been exposed to unsafe levels of isocyanates or had developed isocyanate sensitization. The authors recommend specific measures to improve the conditions at this site.

Journal Article
Journal Article

Hazard Evaluation and Technical Assistance Report No. HETA-89-276-L2093, Lockheed Aeronautical Systems Company, Marietta, Georgia

Authors: Salisbury, S; Bernard, BP; Wilcox, T; Gunter, B (2093) HERO ID: 1516371

[Less] In response to a request from the International Association of Machinists and Aerospace Workers, NIOSH . . . [More] In response to a request from the International Association of Machinists and Aerospace Workers, NIOSH conducted an evaluation at the Lockheed Aeronautical Systems Company, Marietta, Georgia due to concerns about health hazards from exposure to epoxy and polyurethane paints being sprayed in open areas on the C-130 aircraft assembly line. About 350 employees worked on the final assembly line. Air samples were collected to evaluate potential exposures to diisocyanates, organic vapors, and trace metals released during painting operations. Environmental sampling demonstrated minimal risk of exposure for nonpainters to organic vapors, isocyanate prepolymers, and toxic metals released into the open atmosphere during first shift painting of wing panels. Area monitors showed airborne concentrations of organic vapors and hazardous particulates which were below current occupational limits. Exposure risks to hexavalent chromium (7440473) compounds were shown for one of the painters spraying primer containing strontium-chromate (7789062). The large interior volume of the building and the rapid dispersion and upward drift of paint overspray may tend to reduce the chance of floor level exposures. The practice of spraying polyurethane when the building was mostly unoccupied should prevent new cases of respiratory sensitization to diisocyanates among the C-130 production workers. The authors recommend specific measures to reduce exposures to diisocyanates and hexavalent chromium compounds.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Development of an exposure indicator to hexavalent chromium: An in vitro evaluation with human blood

Authors: Devoy, J; Cosnier, F; Bonfanti, E; Lambert-Xolin, AM; Sponne, I; Nunge, H; Mueller, S; Melczer, M; Antoine, G; Remy, A; Viton, S; Grossmann, S; Michaud, S (2017) Toxicology Letters 280:S178-S178. HERO ID: 4453189


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Exposure to CrVI During Early Pregnancy Increases Oxidative Stress and Disrupts the Expression of Antioxidant Proteins in Placental Compartments

Authors: Banu, SK; Stanley, JA; Sivakumar, KK; Arosh, JoeA (2017) HERO ID: 3841281


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Can chromium in red blood cells be used as an indicator of exposure to hexavalent chromium? An in vitro investigation

Authors: Devoy, J; Melczer, M; Antoine, G; Mueller, S; Lambert-Xolin, AM; Langonne, I; Sponne, I; Bonfanti, E; Grossmann, S; Michaux, S; Nunge, H; Viton, S; Remy, A; Cosnier, F (2016) HERO ID: 3841290


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Toxicity assessment of mixture Cr(VI)/Fe(II) on Artemia franciscana under pH variations

Authors: Cortes Tellez, AA; Estevez Delgado, G; Sanchez-Fortun, S; Bartolome Camacho, C (2016) HERO ID: 3841293


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

The role of centrosomes in chemical carcinogenesis: Hexavalent chromium induces aberrant centriole and centrosome separation and centrosome amplification

Authors: Martino, J; Holmes, A; Wise, SS; Xie, H; Wise, JP, Sr (2016) HERO ID: 3841309


Technical Report
Technical Report

Mechanism of prenatal chromium-VI exposure and germ cell apoptosis in the ovary

Author: Banu, S (2016) In RePORTER Database National Institutes of Health. HERO ID: 3841357

[Less] DESCRIPTION (provided by applicant): In utero exposure to environmental endocrine disrupting chemicals . . . [More] DESCRIPTION (provided by applicant): In utero exposure to environmental endocrine disrupting chemicals (EDCs) during prenatal development results in germ cell loss, oocyte damage, early menopause, and increased miscarriages in F1 progeny. Hexavalent chromium (CrVI) is a heavy metal endocrine disruptor. CrVI levels in drinking water sources in the United States have been increasing due to increased industrial use of CrVI and improper disposal of industrial waste, imposing a major threat to human health. Cr traverses the placental barrier and reaches the growing fetus in utero, affecting embryonic development, fetal viability, and reproductive functions. Women exposed to CrVI through environmental or occupational exposures suffer from gynecological illnesses such as abnormal menses, increased postpartum bleeding, pre-term birth, stillbirth, and infertility, accompanied by high Cr levels in their urine peripheral and umbilical cord blood, and placental tissue. Cr can reach the ovary and accumulate in the follicular fluid in women. This significant occupational and public health concerns underscore the importance of understanding CrVI-induced reproductive dysfunctions. The objective of the proposed research is to understand the molecular, cellular, and epigenetic mechanisms by which prenatal exposure to CrVI disrupts germ cell survival, germ cell nest breakdown and early events of follicular development, oocyte quality, and blastocyst development in F1 progeny. The overarching hypothesis is that prenatal exposure to CrVI increases apoptosis of germ cells, accelerates germ cell nest breakdown, impairs oocyte quality, and disrupts blastocyst development in F1 progeny. Specific Aim 1 will determine the molecular and cellular mechanism of prenatal exposure to CrVI on germ cell apoptosis and germ cell nest breakdown in F1 progeny. Specific Aim 2 will establish the selective and interactive roles of reactive oxygen species (ROS), p53, and caspase-3 pathways in CrVI-induced germ cell apoptosis and germ cell nest breakdown. Specific Aim 3 will determine the impact of prenatal exposure to CrVI on oocyte quality and early embryonic development in F1 progeny. The experimental approaches include exposure to environmentally relevant and regulatory doses of CrVI during fetal ovarian development using in vivo rat models, in vitro fetal whole ovary organ culture, pharmacological and genomic approaches, superovulation, oocyte and blastocyst developmental competence and cellular, molecular, and microscopy-based techniques. The novel findings from this project are expected to fill the gap in knowledge needed to understand how the in utero exposure to CrVI affects reproductive functions in the F1 progeny. Results will identify the effect of CrVI on early windows of great vulnerability of fetal ovarian development, and this new knowledge may help to educate pregnant women to avoid exposures to CrVI during such critical windows. The experimental model used and outcomes identified in this study can be extrapolated to understand the adverse effects of other heavy metals and EDCs on ovarian development and prenatal programming of health and disease across the mammalian species including human.