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Diisobutyl Phthalate (DIBP) Final

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53 References Were Found:

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Occurrence, removal and health risk assessment of phthalate esters in the process streams of two different wastewater treatment plants in Lagos and Ogun States, Nigeria

Authors: Olujimi, OO; Aroyeun, OA; Akinhanmi, TF; Arowolo, TA (2017) Environmental Monitoring and Assessment 189:345. HERO ID: 3859033

[Less] Phthalate esters (PEs) are one of the environmentally active organic pollutants capable of causing endocrine . . . [More] Phthalate esters (PEs) are one of the environmentally active organic pollutants capable of causing endocrine disruption. The levels of PE congeners were determined in the influent and effluent from Covenant Oxidation Pond (COP) and Ikeja Wastewater Treatment Plant (IWWTP). Standard methods were adopted for determining the physical and chemical parameters of the water samples. The water samples for PE congener's determination were collected, acidified and stored at 4 °C prior to liquid-liquid extraction and analysis by gas chromatograph. The possible health risk associated with the usage of effluent-polluted river water was also investigated. The pH and temperature ranges were within the Federal Ministry of Environment (FME) 2001 guideline limits while the dissolved oxygen, biochemical oxygen demand and chemical oxygen demand were above the limits. The IWWTP performed better at removing PEs at 54% compared to 43.3% on average at COP. The health risk of individual PE congener showed no non-cancer effects (HQ) as the values varied from 5.01E-05 (DAP) to 1.52E-02 (DEHP) for adults and 1.17E-04 (DAP) to 3.76E-03 (DBP) for children at COP, while at IWWTP, it ranged from 8.06E-05 (DIBP) to 1.09E-02 (DEHP) for adults and 5.68E-04 (MMP) to 2.54E-02 (DEHP) for children. Notwithstanding, the usage of effluent-polluted river water by local communities downstream may result in carcinogenic effects due to the cumulative effects of the PE congeners as the values obtained for adults and children for the ingestion and dermal routes for the two waste process streams ranged from 4.67E-06 (IWWTP) to 6.22E-05 (IWWTP) and 2.18E-05 (IWWTP) to 7.18E-05 (COP), respectively.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Urinary concentrations of 25 phthalate metabolites in Brazilian children and their association with oxidative DNA damage

Authors: Rocha, BA; Asimakopoulos, AG; Barbosa, F; Kannan, K (2017) Science of the Total Environment 586:152-162. HERO ID: 3531624

[Less] Exposure of humans to phthalates has received considerable attention due to the ubiquitous occurrence . . . [More] Exposure of humans to phthalates has received considerable attention due to the ubiquitous occurrence and potential adverse health effects of these chemicals. Nevertheless, little is known about the exposure of the Brazilian population to phthalates. In this study, concentrations of 25 phthalate metabolites were determined in urine samples collected from 300 Brazilian children (6-14years old). Further, the association between urinary phthalate concentrations and a biomarker of oxidative stress, 8-hydroxy-2'-deoxyguanosine (8OHDG), was examined. Overall, eleven phthalate metabolites were found in at least 95% of the samples analyzed. The highest median concentrations were found for monoethyl phthalate (mEP; 57.3ngmL(-1)), mono-(2-ethyl-5-carboxypentyl) phthalate (mECPP; 52.8ngmL(-1)), mono-isobutyl phthalate (mIBP; 43.8ngmL(-1)), and mono-n-butyl phthalate (mBP; 42.4ngmL(-1)). The secondary metabolites of di(2-ethylhexyl) phthalate (DEHP), and mEP, mIBP, and mBP were the most abundant compounds, accounting for >90% of the total concentrations. On the basis of the measured concentrations of urinary phthalate metabolites, we estimated daily intakes of the parent phthalates, which were 0.3, 1.7, 1.8, 2.1, and 7.2μg/kg-bw/day for dimethyl phthalate, di-n-butyl phthalate, diisobutyl phthalate, diethyl phthalate, and DEHP, respectively. Approximately one-quarter of the Brazilian children had a hazard index of >1 for phthalate exposures. Statistically significant positive associations were found between 8OHDG and the concentration of the sum of phthalate metabolites, sum of DEHP metabolites, mEP, mIBP, mBP, monomethyl phthalate, mono(3-carboxypropyl) phthalate, monobenzyl phthalate, monocarboxyoctyl phthalate, monocarboxynonyl phthalate, monoisopentyl phthalate, and mono-n-propyl phthalate. To the best of our knowledge, this is the first study to report the exposure of a Brazilian population to phthalates.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Urinary phthalate metabolites over the first 15 months of life and risk assessment - CHECK cohort study

Authors: Kim, S; Lee, J; Park, J; Kim, HJ; Cho, GJ; Kim, GH; Eun, SH; Lee, JJ; Choi, G; Suh, E; Choi, S; Kim, S; Kim, SK; Kim, YD; Kim, SY; Kim, S; Eom, S; Moon, HB; Kim, S; Choi, K (2017) Science of the Total Environment 607-608:881-887. HERO ID: 3859052

[Less] Phthalates are important group of endocrine disruptors. Infants and young children are susceptible to . . . [More] Phthalates are important group of endocrine disruptors. Infants and young children are susceptible to phthalate exposure. However, information on the phthalate exposure during the early stages of life is very limited. This study was conducted to understand the temporal trend of exposure to major phthalates among infants of Korea during the first 15months after birth, and to estimate associated risks. A total of 286 urine samples were collected from 171 children at 3, 9, 12, or 15 months of age, with 77 children sampled for two or more times. Four phthalates, i.e., di(2-ethylhexyl) phthalate (DEHP), di-isobutyl phthalate (DiBP), di-n-butyl phthalate (DnBP), and diethyl phthalate (DEP) were chosen, and their major metabolites were analyzed in the urine. The DEHP metabolites were detected in 100% of the urine samples at relatively higher levels compared to those reported in other countries. The levels of mono-ethyl phthalate (MEP) were generally lower. Urinary concentrations of most phthalate metabolites, especially DEHP metabolites, increased as children grew older. Intra-class correlation coefficients (ICCs) calculated for DEHP metabolites over time were high (0.7-0.8), suggesting persistence of consistent exposure sources during this sensitive period of life. Hazard quotient (HQ) and hazard index (HI) were calculated from daily intake estimates divided by recommended toxicity thresholds. Among the study population, 4, 16, and 26% of the children showed HI >1 at 9, 12, and 15months of age, respectively. DEHP exposure explained most of the risk estimates. Considering vulnerability of young children to endocrine disruption, efforts to identify sources of exposure and to develop appropriate mitigation options are warranted.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Estimated daily intake and cumulative risk assessment of phthalates in the general Taiwanese after the 2011 DEHP food scandal

Authors: Chang, JW; Lee, CC; Pan, WH; Chou, WC; Huang, HB; Chiang, HC; Huang, PC (2017) Scientific Reports 7:45009. HERO ID: 3859025

[Less] A food scandal occurred in Taiwan in 2011 because the DEHP (di-2-ethylhexyl phthalate) had been intentionally . . . [More] A food scandal occurred in Taiwan in 2011 because the DEHP (di-2-ethylhexyl phthalate) had been intentionally used in food products. We assessed the daily intakes (DIs) and cumulative risk of phthalates in Taiwan's general population after the scandal. The DIs of 6 phthalates, including di-n-butyl phthalate (DnBP), di-iso-butyl phthalate (DiBP), and DEHP, were evaluated using urinary phthalate metabolites. Hazard quotients of phthalates classified as affecting the reproductive (HQrep) and hepatic (HQhep) systems were assessed using cumulative approach. The creatinine-based model showed that the highest DI values in children 7-to 12- years-old were for DEHP (males: median: 4.79 μg/kg bw/d; females: median: 2.62 μg/kg bw/d). The 95(th) percentile (P95) of HQrep values were all >1 in the 7- to 12-year-old and 18- to 40-year-old male groups. The P95 of HQhep values were all >1 in the 7- to 18- year-old male groups. Most of the HQrep was attributable to the HQs of DnBP and DiBP (53.9-84.7%), and DEHP contributed most to HQhep (83.1-98.6%), which reveals that DnBP, DiBP and DEHP were the main risk of phthalate exposure for Taiwanese. Taiwan's general population is widely exposed to DnBP, DiBP and DEHP, especially for young children.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Contamination of phthalate esters in vegetable agriculture and human cumulative risk assessment

Authors: Chen, N; Shuai, WJ; Hao, XM; Zhang, HC; Zhou, DM; Gao, JA (2017) Pedosphere 27:439-451. HERO ID: 3859589

[Less] Phthalate esters (PAEs), which can disturb human endocrine system, have been widely detected in vegetable . . . [More] Phthalate esters (PAEs), which can disturb human endocrine system, have been widely detected in vegetable greenhouse agriculture in China. To investigate the effects of environmental factors on PAEs in soils, pollution sources were identified, and the cumulative risks of PAEs to humans through vegetables in the diet were evaluated in this study. Ninety-eight vegetable samples were collected from 10 markets along with 128 vegetable and 111 soil samples from agricultural greenhouses and open field. All soil and vegetable. samples were contaminated with PAEs, and the total concentrations of the 5 PAEs, including dimethyl phthalate (DMP), diethyl phthalate (DEP), di-iso-butyl phthalate (DiBP), di-n-butyl phthalate (DnBP), and di-2-ethylhexyl phthalate (DEHP), were in the ranges of 0.26-2.53 mg kg(-1) for soils and 0.95-8.09 mg kg(-1) for vegetables. Three components extracted from principle component analysis could explain 51.2%, 19.8%, and 15.3% of the total variance of the 5 PAEs in soils, which may represent three major sources of PAEs, i.e., wastewater irrigation, application of fertilizers and pesticides, and plastic film. Long-term greenhouse cultivation could accumulate DEHP in soils, and a higher soil FeOx content reduced the DnBP concentration. Based on a survey of,vegetables in the diet, the hazard index of PAEs was < 0.15 for individuals in different cities. The exposure of PAEs through vegetable intake was higher than the total exposure from other food stuffs, inhalation, and dermal absorption. More attention should be given to controlling PAEs in greenhouse vegetables.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Indoor phthalate concentration in residential apartments in Chongqing, China: Implications for preschool children's exposure and risk assessment - Supplementary material

Authors: Bu, Z; Zhang, Y; Mmereki, D; Yu, Wei; Li, B (2016) Atmospheric Environment 127. [Supplemental Data] HERO ID: 3479726


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Supplemental materials: Dietary exposure and human risk assessment of phthalate esters based on total diet study in Cambodia

Authors: Cheng, Z; Li, HH; Wang, HS; Zhu, XM; Sthiannopkao, S; Kim, KW; Yasin, MS; Hashim, JH; Wong, MH (2016) Environmental Research 150. [Supplemental Data] HERO ID: 3798840


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Supporting information for: Phthalate esters in soil, plastic film, and vegetable from greenhouse vegetable production bases in Beijing, China: Concentrations, sources, and risk assessment

Authors: Li, C; Chen, J; Wang, J; Han, P; Luan, Y; Ma, X; Lu, A (2016) Science of the Total Environment 568. [Supplemental Data] HERO ID: 3798892


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Supplementary information: Evaluation of exposure to phthalate esters and DINCH in urine and nails from a Norwegian study population

Authors: Giovanoulis, G; Alves, A; Papadopoulou, E; Cousins, AP; Schütze, A; Koch, HM; Haug, LS; Covaci, A; Magnér, J; Voorspoels, S (2016) Environmental Research 151. [Supplemental Data] HERO ID: 3798888


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Phthalate esters in soil, plastic film, and vegetable from greenhouse vegetable production bases in Beijing, China: Concentrations, sources, and risk assessment

Authors: Li, C; Chen, J; Wang, J; Han, P; Luan, Y; Ma, X; Lu, A (2016) Science of the Total Environment 568:1037-1043. HERO ID: 3350219

[Less] The increased use of plastic film in greenhouse vegetable production (GVP) could result in phthalate . . . [More] The increased use of plastic film in greenhouse vegetable production (GVP) could result in phthalate ester (PAE) contamination in vegetables. However, limited information is currently available on their occurrence and associated potential risks in GVP systems. The present study documents the occurrence and composition of 15 PAEs in soil, plastic film, and vegetable samples from eight large-scale GVP bases in Beijing, China. Results showed that PAEs are ubiquitous contaminants in these GVP bases. Total PAE concentrations ranged from 0.14 to 2.13mg/kg (mean 0.99mg/kg) in soils and from 0.15 to 6.94mg/kg (mean 1.49mg/kg) in vegetables. Di (2-ethylhexyl) phthalate, di-n-butyl phthalate, and diisobutyl phthalate were the most abundant components, which accounted for >90% of the total PAEs. This investigation also indicated that the widespread application of plastic film in GVP systems may be the primary source of these PAEs. The non-cancer and carcinogenic risks of target PAEs were estimated based on the exposures of vegetable intake. The hazard quotients of PAE in all vegetable samples were lower than 1 and the carcinogenic risks were also at acceptable levels for consumers. The data in this study can provide valuable information to understand the status of potential pollutants, specifically PAEs, in GVP systems.