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Diisobutyl Phthalate (DIBP) Final

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297 References Were Found:

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Supplementary material: Phthalate metabolites in 24-h urine samples of the German Environmental Specimen Bank (ESB) from 1988 to 2015 and a comparison with US NHANES data from 1999 to 2012

Authors: Koch, HM; Rüther, M; Schütze, A; Conrad, A; Pälmke, C; Apel, P; Brüning, T; Kolossa-Gehring, M (In Press) International Journal of Hygiene and Environmental Health. [Supplemental Data] HERO ID: 3798891


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Occurrence and Profiles of Phthalates in Foodstuffs from China and Their Implications for Human Exposure

Authors: Guo, Y; Zhang, Z; Liu, L; Li, Y; Ren, N; Kannan, K (In Press) Journal of Agricultural and Food Chemistry. HERO ID: 1311703

[Less] Phthalate esters are used in a wide variety of consumer products, and human exposure to this class of . . . [More] Phthalate esters are used in a wide variety of consumer products, and human exposure to this class of compounds is widespread. Nevertheless, studies on dietary exposure of humans to phthalates are limited. In this study, nine phthalate esters were analyzed in eight categories of foodstuffs (n = 78) collected from Harbin and Shanghai, China, in 2011. Dimethyl phthalate (DMP), diethyl phthalate (DEP), dibutyl phthalate (DBP), diisobutyl phthalate (DIBP), benzyl butyl phthalate (BzBP), and diethylhexyl phthalate (DEHP) were frequently detected in food samples. DEHP was the major compound found in most of the food samples, with concentrations that ranged from below the limit of quantification (LOQ) to 762 ng/g wet weight (wt). The concentrations of phthalates in food samples from China were comparable to concentrations reported for several other countries, but the profiles were different; DMP was found more frequently in Chinese foods than in foods from other countries. The estimated daily dietary intake of phthalates (EDI(diet)) was calculated based on the concentrations measured and the daily ingestion rates of food items. The EDI(diet) values for DMP, DEP, DIBP, DBP, BzBP, and DEHP (based on mean concentrations) were 0.092, 0.051, 0.505, 0.703, 0.022, and 1.60 μg/kg-bw/d, respectively, for Chinese adults. The EDI(diet) values calculated for phthalates were below the reference doses suggested by the United States Environmental Protection Agency (EPA). Comparison of total daily intakes, reported previously based on a biomonitoring study, with the current dietary intake estimates suggests that diet is the main source of DEHP exposure in China. Nevertheless, diet accounted for only <10% of the total exposure to DMP, DEP, DBP, and DIBP, which suggested the existence of other sources of exposure to these phthalates.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Estimating uptake of phthalate ester metabolites into the human nail plate using pharmacokinetic modelling - Supplementary material

Authors: Bui, TT; Alves, A; Palm-Cousins, A; Voorspoels, S; Covaci, A; Cousins, IT (2017) Environment International 100. [Supplemental Data] HERO ID: 3798199


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Predicting the gas-phase concentration of semi-volatile organic compounds from airborne particles: Application to a French nationwide survey - Supporting informatoin

Authors: Wei, W; Mandin, C; Blanchard, O; Mercier, F; Pelletier, M; Le Bot, B; Glorennec, P; Ramalho, O (2017) Science of the Total Environment 576. [Supplemental Data] HERO ID: 3798202


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Urinary levels of phthalate metabolites and associations with demographic characteristics in Korean adults

Authors: Lee, KM; Kho, Y; Kim, PG; Park, SH; Lee, JH (2017) Environmental Science and Pollution Research 24:14669-14681. HERO ID: 3859032

[Less] The objective of this study is to assess human exposure to phthalates and its associations with demographic . . . [More] The objective of this study is to assess human exposure to phthalates and its associations with demographic characteristics of the subjects in the Korean National Human Biomonitoring Survey. The subjects aged between 18 and 69 were selected through nationwide stratified sampling. A total of 1874 urine samples were collected and stored at -20 °C until measurement for ten selected metabolites of phthalates (MnBP, MiBP, MBzP, MCHP, MnOP, MEHP, MEOHP, MEHHP, MiNP, and MiDP) using high-performance liquid chromatography-tandem mass spectrometry (LC-MS/MS). The difference in the level of urinary phthalate metabolites by the characteristics of the subjects was tested for statistical significance using SAS Surveyreg procedure. The coefficients and standard errors from multiple linear regressions were exponentiated to estimate the adjusted proportional change (APC) and 95% CIs compared with a referent level. The proportion of data above LOQ was less than 20% for MCHP, MnOP, MiNP, and MiDP. Geometric means of creatinine-adjusted concentrations (unit: μg/g creatinine) of six other phthalate metabolites among Korean adults were 41.7 (95% CI 39.6-43.9) for MnBP, 17.1 (95% CI 16.1-18.1) for MiBP, 15.7 (95% CI 14.4-17.1) for MBzP, 8.65 (95% CI 8.10-9.22) for MEHP, 17.5 (95% CI 16.8-18.3) for MEOHP, and 38.1 (95% CI 36.2-40.2) for MEHHP. Urinary level of phthalates tended to be higher among subjects with older age, females, and those with vigorous daily physical activity and tended to be lower among drinkers and those with higher income. Our results suggest that the level of phthalate exposure is significant among Korean adults and thus warrants further studies to identify major source and route of exposure to phthalates.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Phthalate release in leachate from municipal landfills of central Poland

Authors: Wowkonowicz, P; Kijeńska, M (2017) PLoS ONE 12:e0174986. HERO ID: 3859036

[Less] Phthalate diesters (PAEs) are used as plasticizer additives to polymer chains to make the material more . . . [More] Phthalate diesters (PAEs) are used as plasticizer additives to polymer chains to make the material more flexible and malleable. PAEs are bonded physically, not chemically, to the polymeric matrix and can migrate to and leach from the product surface, posing a serious danger to the environment and human health. There have been a number of studies on PAE concentrations in landfill leachate conducted in the EU and around the world, though few in Poland. In the present study, the leachate of five municipal landfills was analyzed for the presence of PAEs. Raw leachate was sampled four times over the period of one year in 2015/16. It was the first large study on this subject in Poland. PAEs were detected in the leachate samples on all of the landfills, thereby indicating that PAEs are ubiquitous environmental contaminants. The following PAEs were detected in at least one sample: Di(2-ethylhexyl) phthalate (DEHP), Diethyl phthalate (DEP), Dimethyl phthalate (DMP), Di-n-butyl phthalate (DBP), Di-isobutylphthalate (DIBP). Out of all ten PAEs, DEHP was the most predominant, with concentrations up to 73.9 μg/L. DEHP was present in 65% of analyzed samples (in 100% of samples in spring, 80% in winter, and 40% in summer and autumn). In only 25% of all samples DEHP was below the acceptable UE limit for surface water (1.3 μg/L), while 75% was from 1.7 to 56 times higher than that value. On the two largest landfills DEHP concentrations were observed during samples from all four seasons, including on a landfill which has been remediated and closed for the last 5 years.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Exposure of children to phthalates and the impact of consumer practices in Slovakia

Authors: Šidlovská, M; Petrovičová, I; Kolena, B; Pilka, T; Šovčíková, E; Trnovec, T (2017) Reviews on Environmental Health 32:211-214. HERO ID: 3859080

[Less] Phthalates are environmental pollutants that can enter the human body by ingestion, inhalation and dermal . . . [More] Phthalates are environmental pollutants that can enter the human body by ingestion, inhalation and dermal absorption. Food constitutes the most important source of human exposure to these chemicals. The aim of our study was the biological monitoring of exposure to eight phthalate metabolites in children (n=107), 10-12 years of age, living in eastern Slovakia. Additionally, we analysed some associations between anthropometric measures, questionnaire data (i.e. eating and drinking habits, practice of personal care products) and concentrations of phthalate metabolites. Because of the short half-life of phthalates, within 24-48 h, we used 24-h recalls to assess dietary intakes. We used high-performance liquid chromatography and tandem mass spectrometry for the analysis of spot urine samples to determine concentrations of phthalate metabolites mono-ethyl phthalate (MEP), mono-n-butyl phthalate, mono-iso-butyl phthalate, mono-benzyl phthalate (MBzP), mono (2-ethyl-5-hydroxyhexyl) phthalate (5OH-MEHP), mono(2-ethyl-5-oxohexyl) phthalate (5oxo-MEHP), mono-carboxy pentyl and mono (2-ethylhexyl) phthalate (MEHP). We found statistically significant association between consumer practices and concentration of some phthalate metabolites, concretely consumption of milk and dairy products with MBzP and margarine with MEP (p<0.01 in both cases) and margarine with 5oxo-MEHP, hot beverages with 5OH-MEHP, baguettes and semifinished products with MEP (p<0.05 in all cases). Further, we found relationship between use of cosmetic products and phthalate concentrations, nail polish application and MEP and use of body lotion and MEHP (p<0.05 in both cases). We concluded that consumer practices (including eating and drinking habits and personal care) represent the substantial source of phthalate exposure in Slovak children.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Exposure sources and their relative contributions to urinary phthalate metabolites among children in Taiwan

Authors: Chen, CC; Wang, YH; Wang, SL; Huang, PC; Chuang, SC; Chen, MH; Chen, BH; Sun, CW; Fu, HC; Lee, CC; Wu, MT; Chen, ML; Hsiung, CA (2017) International Journal of Hygiene and Environmental Health 220:869-879. HERO ID: 3859066

[Less] Phthalate exposure is omnipresent and known to have developmental and reproductive effects in children. . . . [More] Phthalate exposure is omnipresent and known to have developmental and reproductive effects in children. The aim of this study was to determine the phthalate exposure sources and their relative contributions among children in Taiwan. During the first wave of the Risk Assessment of Phthalate Incident in Taiwan (RAPIT), in 2012, we measured 8 urinary phthalate metabolites in 226 children aged 1-11 years old and in 181 children from the same cohort for the wave 2 study in 2014. A two-stage statistical analysis approach was adopted. First, a stepwise regression model was used to screen 80 questions that explored the exposure frequency and lifestyle for potential associations. Second, the remaining questions with positive regression coefficients were grouped into the following 6 exposure categories: plastic container/packaging, food, indoor environment, personal care products, toys, and eating out. A mixed model was then applied to assess the relative contributions of these categories for each metabolite. The use of plastic container or food packaging were dominant exposure sources for mono-2-ethylhexyl phthalate (MEHP), mono-2-ethyl-5-hydroxyhexyl phthalate (MEHHP), mono-2-ethyl-5-oxohexyl phthalate (MEOHP), and mono-n-butyl phthalate (MnBP). The indoor environment was a major exposure source of mono-methyl phthalate (MMP), mono-benzyl phthalate (MBzP), and mono-isobutyl phthalate (MiBP). The consumption of seafood showed a significant correlation with MEHP. The children's modified dietary behavior and improved living environment in the second study wave were associated with lower phthalate metabolite levels, showing that phthalate exposures can be effectively reduced.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Predicting the gas-phase concentration of semi-volatile organic compounds from airborne particles: Application to a French nationwide survey

Authors: Wei, W; Mandin, C; Blanchard, O; Mercier, F; Pelletier, M; Le Bot, B; Glorennec, P; Ramalho, O (2017) Science of the Total Environment 576:319-325. HERO ID: 3454652

[Less] Semi-volatile organic compounds (SVOCs) partition indoors between the gas phase, airborne particles, . . . [More] Semi-volatile organic compounds (SVOCs) partition indoors between the gas phase, airborne particles, settled dust, and other surfaces. Unknown concentrations of SVOCs in the gas phase (Cg) can be predicted from their measured concentrations in airborne particles. In previous studies, the prediction of Cg depended largely on choosing a specific equation for the calculation of the particle/gas partition coefficient. Moreover, the prediction of Cg is frequently performed at a reference temperature rather than the real indoor temperature. In this paper, a probabilistic approach based on Monte Carlo simulation was developed to predict the distribution of SVOCs' Cg from their concentrations in airborne particles at the target indoor temperature. Moreover, the distribution of the particle/gas partition coefficient of each SVOC at the target temperature was used. The approach was validated using two measured datasets in the literature: the predicted Cg from concentrations measured in airborne particles and the measured Cg were generally of the same order of magnitude. The distributions of the Cg of 66 SVOCs in the French housing stock were then predicted. The SVOCs with the highest median Cg, ranging from 1ng/m(3) to >100ng/m(3), included 8 phthalates (DEP, DiBP, DBP, DEHP, BBP, DMP, DiNP, and DMEP), 4 polycyclic aromatic hydrocarbons (fluorene, phenanthrene, fluoranthene, and anthracene), 2 alkylphenols (4-tert-butylphenol and 4-tert-octylphenol), 2 synthetic musks (galaxolide and tonalide), tributyl phosphate, and heptachlor. The nationwide, representative, predicted Cg values of SVOCs are frequently of the same order of magnitude in Europe and North America, whereas these Cg values in Chinese and Indian dwellings and the Cg of polybrominated diphenyl ethers in U.S. dwellings are generally higher.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Contamination of Phthalate Esters in Vegetable Agriculture and Human Cumulative Risk Assessment

Authors: Chen Ning; Shuai Wenjuan; Hao Xinmei; Zhang Huichun; Zhou Dongmei; Gao Juan (2017) Pedosphere 27:439-451. HERO ID: 3859589

[Less] Phthalate esters (PAEs), which can disturb human endocrine system, have been widely detected in vegetable . . . [More] Phthalate esters (PAEs), which can disturb human endocrine system, have been widely detected in vegetable greenhouse agriculture in China. To investigate the effects of environmental factors on PAEs in soils, pollution sources were identified, and the cumulative risks of PAEs to humans through vegetables in the diet were evaluated in this study. Ninety-eight vegetable samples were collected from 10 markets along with 128 vegetable and 111 soil samples from agricultural greenhouses and open field. All soil and vegetable. samples were contaminated with PAEs, and the total concentrations of the 5 PAEs, including dimethyl phthalate (DMP), diethyl phthalate (DEP), di-iso-butyl phthalate (DiBP), di-n-butyl phthalate (DnBP), and di-2-ethylhexyl phthalate (DEHP), were in the ranges of 0.26-2.53 mg kg(-1) for soils and 0.95-8.09 mg kg(-1) for vegetables. Three components extracted from principle component analysis could explain 51.2%, 19.8%, and 15.3% of the total variance of the 5 PAEs in soils, which may represent three major sources of PAEs, i.e., wastewater irrigation, application of fertilizers and pesticides, and plastic film. Long-term greenhouse cultivation could accumulate DEHP in soils, and a higher soil FeOx content reduced the DnBP concentration. Based on a survey of,vegetables in the diet, the hazard index of PAEs was < 0.15 for individuals in different cities. The exposure of PAEs through vegetable intake was higher than the total exposure from other food stuffs, inhalation, and dermal absorption. More attention should be given to controlling PAEs in greenhouse vegetables.