Health & Environmental Research Online (HERO)


Methylmercury


43,978 References Were Found:

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Methylmercury-induced developmental toxicity is associated with oxidative stress and cofilin phosphorylation. Cellular and human studies

Authors: Caballero, B; Olguin, N; Campos, F; Farina, M; Ballester, F; Lopez-Espinosa, MJ; Llop, S; Rodríguez-Farré, E; Suñol, C (In Press) NeuroToxicology. HERO ID: 3456423

[Less] Environmental exposure to methylmercury (MeHg) during development is of concern because it is easily . . . [More] Environmental exposure to methylmercury (MeHg) during development is of concern because it is easily incorporated in children's body both pre- and post-natal, it acts at several levels of neural pathways (mitochondria, cytoskeleton, neurotransmission) and it causes behavioral impairment in child. We evaluated the effects of prolonged exposure to 10-600nM MeHg on primary cultures of mouse cortical (CCN) and of cerebellar granule cells (CGC) during their differentiation period. In addition, it was studied if prenatal MeHg exposure correlated with altered antioxidant defenses and cofilin phosphorylation in human placentas (n=12) from the INMA cohort (Spain). Exposure to MeHg for 9days in vitro (DIV) resulted in protein carbonylation and in cell death at concentrations ≥200nM and ≥300nM, respectively. Exposure of CCN and CGC to non-cytotoxic MeHg concentrations for 5 DIV induced an early concentration-dependent decrease in cofilin phosphorylation. Furthermore, in both cell types actin was translocated from the cytosol to the mitochondria whereas cofilin translocation was found only in CGC. Translocation of cofilin and actin to mitochondria in CGC occurred from 30nM MeHg onwards. We also found an increased expression of cortactin and LIMK1 mRNA in CGC but not in CCN. All these effects were prevented by the antioxidant probucol. Cofilin phosphorylation was significantly decreased and a trend for decreased activity of glutathione reductase and glutathione peroxidase was found in the fetal side of human placental samples from the highest (20-40μg/L) MeHg-exposed group when compared with the low (<7μg/L) MeHg-exposed group. In summary, cofilin dephosphorylation and oxidative stress are hallmarks of MeHg exposure in both experimental and human systems.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Trace elements in animal-based food from Shanghai markets and associated human daily intake and uptake estimation considering bioaccessibility

Authors: Lei, B; Chen, L; Hao, Y; Cao, T; Zhang, X; Yu, Y; Fu, J (In Press) Ecotoxicology and Environmental Safety. HERO ID: 1797781

[Less] The concentrations of four human essential trace elements [iron (Fe), manganese (Mn), zinc (Zn), chromium . . . [More] The concentrations of four human essential trace elements [iron (Fe), manganese (Mn), zinc (Zn), chromium (Cr)] and non-essential elements [cadmium (Cd), lead (Pb), arsenic (As), and mercury (Hg)] in eighteen animal-based foods including meat, fish, and shellfish collected from markets in Shanghai, China, were analyzed, and the associated human daily intake and uptake considering bioaccessibility were estimated. The mean concentration ranges for eight trace elements measured in the foods were 3.98-131µgg(-1) for Fe, 0.437-18.5µgg(-1) for Mn, 5.47-53.8µgg(-1) for Zn, none detected-0.101µgg(-1) for Cr, 2.88×10(-4)-2.48×10(-2)µgg(-1) for Cd, 1.18×10(-3)-0.747µgg(-1) for Pb, none detected-0.498µgg(-1) for As, and 8.98×10(-4)-6.52×10(-2)µgg(-1) for Hg. The highest mean concentrations of four human essential elements were all found in shellfish. For all the trace elements, the observed mean concentrations are mostly in agreement with the reported values around the world. The total daily intake of trace elements via ingestion of animal-based food via an average Shanghai resident was estimated as 7371µgd(-1) for the human essential elements and 13.0µgd(-1) for the human non-essential elements, but the uptake decreased to 4826µgd(-1) and 6.90µgd(-1), respectively, after trace element bioaccessibility was considered. Livestock and fish for human essential and non-essential elements, respectively, were the main contributor, no matter whether the bioaccessibility was considered or not. Risk estimations showed that the intake and uptake of a signal trace element for an average Shanghai resident via ingestion animal-based foods from Shanghai markets do not exceed the recommended dietary allowance values; consequently, a health risk situation is not indicated.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Genotypic differences in arsenic, mercury, lead and cadmium in milled rice (Oryza sativa L.)

Authors: Jiang, S; Shi, C; Wu, J (In Press) International Journal of Food Sciences and Nutrition. HERO ID: 1022002

[Less] The contents of arsenic, mercury, lead and cadmium in milled rice were determined. Among 216 genotypes, . . . [More] The contents of arsenic, mercury, lead and cadmium in milled rice were determined. Among 216 genotypes, the As, Hg, Pb and Cd contents were ranged from 5.06 to 296.45, 2.46 to 65.85, 4.16 to 744.95 and 5.91 to 553.40 ng/g, respectively. Six genotypes with lower contents of toxic metal elements were selected. The averages of As and Pb contents for indica rice were higher than those of japonica rice, while the averages of Hg and Cd contents were in contrast. Compared with white brown rice, the milled rice from black and red brown rice contained lower contents of four elements. Significant negative correlation was found between As content and alkaline spread value. Significant correlations were observed between As and aspartic acid (Asp) content, Hg and Asp or leucine contents, Pb and cysteine or methionine contents. Cd content was significantly negatively correlated with protein and 14 amino acid contents.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Toxic element concentrations in the bottlenose (Tursiops truncatus), striped (Stenella coeruleoalba) and Risso's (Grampus griseus) dolphins stranded in eastern Adriatic Sea

Authors: Bilandžić, N; Sedak, M; Đokić, M; Đuras Gomerčić, M; Gomerčić, T; Zadravec, M; Benić, M; Prevendar Crnić, A (In Press) Bulletin of Environmental Contamination and Toxicology. HERO ID: 1255499

[Less] Concentrations of cadmium (Cd), arsenic (As), mercury (Hg) and lead (Pb) were measured in muscle, liver . . . [More] Concentrations of cadmium (Cd), arsenic (As), mercury (Hg) and lead (Pb) were measured in muscle, liver and kidney of three cetacean species, the bottlenose (Tursiops truncatus), striped (Stenella coeruleoalba) and Risso's (Grampus griseus) dolphins from the Croatian waters of the Adriatic Sea. In all three dolphin species Cd levels decreased in tissues in the order: kidney > liver > muscle, while As and Pb decreased in the order: liver > kidney > muscle for striped and Risso's dolphins, but with the order reversed for liver and kidney in the bottlenose dolphin for Pb. Levels of Hg consistently followed the order: liver > muscle > kidney, with mean concentrations in the liver being 11-34 times higher than in the other tissues. The highest mean concentrations of trace elements were measured in Risso's dolphins at 14.9 μg/g wet weight, for Cd in the kidney, and concentrations in the liver of 2.41, 1,115 and 0.63 μg/g for As, Hg and Pb, respectively. Statistically significant differences between the three dolphin species were determined for Cd, Hg and Pb in liver tissues, for As in muscle and for Cd in kidney. Significant correlations of metals between tissues were determined in all three species. The results presented give an indication of the environmental condition with regard to the content of toxic metals along the eastern coast of the Adriatic Sea.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Bioremediation and human tolerance to heavy metals through microbial processes: A potential role for probiotics?

Authors: Monachese, M; Burton, JP; Reid, G (In Press) Applied and Environmental Microbiology. HERO ID: 1255524

[Less] The food and water we consume are often contaminated with a range of chemicals and heavy metals such . . . [More] The food and water we consume are often contaminated with a range of chemicals and heavy metals such as lead, cadmium, arsenic, chromium and mercury that are able to cause debilitating health complications. Though heavy metal exposure and contamination are not a recent phenomenon, the concentration of metals and exposure to populations remains a major issue despite remediation interventions. The ability to prevent and manage this problem is still a subject of much debate with many ineffective technologies and others too expensive for practical large- scale use, especially for developing nations where major pollution occurs. This has led researchers to seek alternative solutions for decontaminating environmental sites and humans themselves. A number of environmental microorganisms have long been known for their ability to bind metals, but less well appreciated are human gastrointestinal bacteria. Species such as Lactobacillus present in the human mouth, gut and vagina and in fermented foods, have the ability to bind and detoxify some of these substances. This review examined the current understanding of detoxication mechanisms of lactobacilli and how in the future humans and animals might benefit from these organisms in remediating environmental contamination of food.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Biosorption of heavy metals by lactic acid bacteria and identification of mercury binding protein

Authors: Kinoshita, H; Sohma, Y; Ohtake, F; Ishida, M; Kawai, Y; Kitazawa, H; Saito, T; Kimura, K (In Press) Research in Microbiology. HERO ID: 1579288

[Less] Heavy metals cause various health hazards. Using lactic acid bacteria (LAB), we tested the biosorption . . . [More] Heavy metals cause various health hazards. Using lactic acid bacteria (LAB), we tested the biosorption of heavy metals e.g. cadmium (Cd) (II), lead (Pb) (II), arsenic (As) (III), and mercury (Hg) (II). Cd (II) sorption was tested in 103 strains using atomic absorption spectrophotometery (AAS). Weissella viridescens MYU 205 (1×10(8) cells/ml) decreased Cd (II) levels in citrate buffer (pH 6.0) from one ppm to 0.459 ± 0.016 ppm, corresponding to 10.46 μg of Cd (II). After screening, 11 LAB strains were tested using various pH (pH 4.0, 5.0, 6.0, 7.0) showing the sorption was acid sensitive; and was cell concentration dependent, where the Cd (II) concentration decreased from one ppm to 0.042 (max) / 0.255 (min) ppm at 1×10(10) cells/ml. Additionally, the biosorption of Pb (II), As (III), and Hg (II) were tested using an inductively coupled plasma mass spectrometer (ICP-MS). The Hg (II) concentration was reduced the most followed by Pb (II) and As (III). Many of the bacterial cell surface proteins of W. viridescens MYU 205 showed binding to Hg (II) using the Hg (II) column assay. Having a CXXC motif, a ∼14 kDa protein may be one of the Hg (II) binding proteins. LAB biosorption may aid the detoxification of people exposed to heavy metals.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

A baseline study of metals in cod (Gadus morhua) from the North Sea and coastal Norwegian waters, with focus on mercury, arsenic, cadmium and lead

Authors: Julshamn, K; Duinker, A; Nilsen, BM; Nedreaas, K; Maage, A (In Press) Marine Pollution Bulletin. HERO ID: 1597305

[Less] This study is one of several baseline studies that will provide basic and reliable information about . . . [More] This study is one of several baseline studies that will provide basic and reliable information about the content of undesirable substances in important species of fish caught in Norwegian waters. Concentrations of metals in the muscle and livers of 516 cod caught at 22 positions in the North Sea were analysed. An additional 687 cod were caught from 13 fjords and coastal areas along the coast of Norway. Three out of 1203 samples of muscle exceeded the maximum limit of 0.5mgHgkg(-1) wet weight set by the EU for foodstuffs. The mercury concentration in cod muscle was higher and the cadmium concentration in the liver was lower in the North Sea and coastal areas in the southern part of Norway than in the Barents Sea and coastal areas in the northern part of Norway. These differences are perhaps caused by differences in the cod diet.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Multiple low-level exposures: Hg interactions with co-occurring neurotoxic substances in early life

Author: Dórea, JG (In Press) Biochimica et Biophysica Acta. General Subjects. [Review] HERO ID: 5101359

[Less] All chemical forms of Hg can affect neurodevelopment; however, low levels of organic Hg (methylmercury-MeHg . . . [More] All chemical forms of Hg can affect neurodevelopment; however, low levels of organic Hg (methylmercury-MeHg and ethylmercury-EtHg in Thimerosal-containing vaccines, hereafter 'TCV') exposures during early life (pregnancy and lactation) co-occur with other environmental neurotoxic substances. These neurotoxicants may act in parallel, synergistically, or antagonistically to Hg. Nevertheless, the risks of neurotoxicity associated with multiple neuro-toxicants depend on type, time, combinations of exposure, and environmental and/or genetic-associated factors. Neurological developmental disorders, delays in cognition and behavioral outcomes associated with multiple exposures (which include Hg) may show transient or lasting outcomes depending on constitutional and/or environmental factors that can interact to neutralize, aggravate or attenuate these effects; often these studies are challenging to interpret. During pregnancy and lactation, fish-MeHg exposure is frequently confounded with the opposing effects of neuroactive nutrients (in fish) that lead to positive, negative, or no effects on neurobehavioral tests. In infancy, exposures to acute binary mixtures (TCV- EtHg and Al-adjuvants in infant immunizations) are associated with increased risks of tics and other developmental disorders. Despite the certitude that promulgates single environmental neurotoxicants, empirical comparisons of combined exposures indicate that Hg-related outcome is uneven. Hg in combination with other neurotoxic mixtures may elevate risks of neurotoxicity, but these risks arise in circumstances that are not yet predictable. Therefore, to achieve the goals of the Minamata treaty and to safeguard the health of children, low levels of mercury exposure (in any chemical form) needs to be further reduced whether the source is environmental (air- and food-borne) or iatrogenic (pediatric TCVs).

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Heavy metals of the Tibetan top soils: Level, source, spatial distribution, temporal variation and risk assessment

Authors: Sheng, J; Wang, X; Gong, P; Tian, L; Yao, T (In Press) Environmental Science and Pollution Research. HERO ID: 1070482

[Less] OBJECTIVE: Due to its high elevation, rare human activities and proximity to south Asia where industries . . . [More] OBJECTIVE: Due to its high elevation, rare human activities and proximity to south Asia where industries are highly developed, it is required to investigate the fragile environment of the Tibetan Plateau. We are aiming to obtain the concentration level, source, spatial distribution, temporal variation and potential environmental risk of Tibetan soils. METHODS: A total of 128 surf ace soil samples were collected and analyzed f or V, Cr, Mn, Co, Ni, Cu, Zn, As, Cd and Pb, and an additional 111 samples were analyzed f or Hg and total organic carbon. Concentration comparisons coupled with multivariate statistics were used to analysis the sources of elements of soils. We also carried out Risk assessment on the soils. RESULTS: Concentrations of Hg, Cr, Ni, Cd and Pb are slightly higher than those of the late 1970s. Concentrations of Cr and Ni are higher than averaged world background values. Tibetan soils present a high natural As concentration level. DISCUSSION: Anthropogenic sources may partly contribute to the elevated Hg, Cd and Pb concentrations. Cr and Ni are mainly originated from soil parent materials. Soil elements in Anduo and Qamdo regions may threaten the health of local people. CONCLUSION: Heavy metal elements of Tibetan Plateau are mainly from the natural source. Arsenic present a high background level. Soil elements in Anduo and Qamdo regions may threaten the health of local people, which should be of concern to scientists and the government.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Organohalogen contaminants and total mercury in forage fish preyed upon by thick-billed murres in northern Hudson Bay

Authors: Braune, BM; Gaston, AJ; Elliott, KH; Provencher, JF; Woo, KJ; Chambellant, M; Ferguson, SH; Letcher, RJ (In Press) Marine Pollution Bulletin. HERO ID: 2149422

[Less] Twelve marine fish species collected from a thick-billed murre (Uria lomvia) breeding colony in northern . . . [More] Twelve marine fish species collected from a thick-billed murre (Uria lomvia) breeding colony in northern Hudson Bay in the Canadian Arctic during 2007-2009 were analyzed for legacy organochlorines (e.g. PCBs, DDT), polybrominated diphenyl ethers (PBDEs), perfluorinated carboxylates (PFCAs) and sulfonates (PFSAs), and total mercury (Hg). No one species of prey fish had the highest levels across all contaminant groups analyzed. For the two pelagic fish species sampled, concentrations of the major organochlorine groups (e.g. Σ21PCB, ΣDDT, ΣCHL, ΣCBz), ΣPBDE, ΣPFCA and Hg were consistently higher in Arctic cod (Boreogadus saida) than in capelin (Mallotus villosus). Biomagnification factors from whole fish to thick-billed murre liver across all species were generally higher for Σ21PCB and ΣDDT. ΣPBDE did not biomagnify.