Health & Environmental Research Online (HERO)


Per- and Polyfluoroalkyl Substances (PFAS)


23 References Were Found:

Technical Report
Technical Report

Environment tier II assessment for perfluorobutanesulfonic acid and its direct precursors

Author: NICNAS (2017) HERO ID: 3860029


Technical Report
Technical Report

Human health tier II assessment for perfluorobutanesulfonate (PFBs) and its direct precursors: 1-butanesulfonic acid, 1,1,2,2,3,3,4,4,4-nonafluoro-, 375-73-5

Author: NICNAS (2017) Australian Government, Department of Health, National Industrial Chemicals Notification and Assessment Scheme. HERO ID: 3860033

[Less] This assessment was carried out under the National Industrial Chemicals Notification and Assessment . . . [More] This assessment was carried out under the National Industrial Chemicals Notification and Assessment Scheme (NICNAS). This scheme has been established by the Industrial Chemicals (Notification and Assessment) Act 1989 (the Act), to aid in the protection of the Australian people and the environment by assessing the risks of industrial chemicals, providing information and making recommendations to promote their safe use.

As part of the reforms regarding Existing Chemicals, NICNAS has implemented a new framework to address the human health and environmental impacts of previously unassessed industrial chemicals listed on the Australian Inventory of Chemical Substances (AICS).

The Inventory Multi-tiered Assessment and Prioritisation (IMAP) framework was developed, with significant input from stakeholders. The framework provides a more rapid, flexible and transparent approach for the assessment of existing chemicals.

Technical Report
Technical Report

Use and potential impacts of AFFF containing PFASs at airports

Authors: Thalheimer, AH; McConney, LB; Kalinovich, IK; Pigott, AV; Franz, JD; Holbert, HT; Mericas, D; Puchacz, ZJ (2017) (ACRP Research Report 173). Washington, DC: National Academies Press. HERO ID: 3860044

[Less] TRB's Airport Cooperative Research Program (ACRP) Research Report 173: Use and Potential Impacts of . . . [More] TRB's Airport Cooperative Research Program (ACRP) Research Report 173: Use and Potential Impacts of AFFF Containing PFASs at Airports explores the potential environmental and health impacts of per- and polyfluoroalkyl substances (PFASs) typically found in aqueous film-forming foams (AFFFs). The report describes methods that can be used to identify areas of potential concern at an airport and ways to implement management and remediation practices.

Technical Report
Technical Report

Safety data sheet. Version 4.2. Nonafluorobutane-1-sulfonic acid. Product number 562629. CAS-No 375-73-5

Author: Sigma-Aldrich (2017) HERO ID: 3980857


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Plasma perfluoroalkyl and polyfluoroalkyl substances concentration and menstrual cycle characteristics in preconception women: Supplemental materials

Authors: Zhou, W; Zhang, L; Tong, C; Fang, F; Zhao, S; Tian, Y; Tao, Y; Zhang, J (2017) Environmental Health Perspectives 125. [Supplemental Data] HERO ID: 3860309

Abstract: Supplementary materials

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Plasma perfluoroalkyl and polyfluoroalkyl substances concentration and menstrual cycle characteristics in preconception women

Authors: Zhou, W; Zhang, L; Tong, C; Fang, F; Zhao, S; Tian, Y; Tao, Y; Zhang, J; Shanghai Birth Cohort Study (2017) Environmental Health Perspectives 125:067012. HERO ID: 3859799

[Less] BACKGROUND: Perfluoroalkyl and polyfluoroalkyl substances (PFASs) are persistent synthetic . . . [More] BACKGROUND: Perfluoroalkyl and polyfluoroalkyl substances (PFASs) are persistent synthetic chemicals that are widely used in industrial applications and often detectable in humans. In rats, PFASs can interfere with the estrous cycle. In humans, menstruation has been viewed as a proxy of female fecundity, and periodic menstruation plays a critical role in endometrial sloughing in the absence of pregnancy and in preparing for embryo implantation.

OBJECTIVES: We investigated the association between PFAS exposure and menstrual cycle characteristics in women who plan to become pregnant.

METHODS: Plasma level of 10 PFASs was measured in 950 women who were attempting to become pregnant and recruited in two preconception care clinics in Shanghai, China, from August 2013 to April 2015. Information on menstrual cycle characteristics was collected by questionnaires. Associations between PFAS levels and menstrual cycle regularity, length, and bleeding volume were examined using multiple logistic regression models.

RESULTS: Pre-pregnant women with higher levels of log-transformed perfluorooctanate (PFOA), perfluorooctane sulfonate (PFOS), perfluorononanoic acid (PFNA), and perfluorohexanesulfonate (PFHxS) had increased odds of self-reported history of irregular menstrual cycle [ (95% CI: 1.08, 2.15); (95% CI: 0.98, 1.70); (95% CI: 1.03, 2.07); (95% CI: 1.17, 2.77)] and long menstrual cycle [ (95% CI: 1.06, 2.10); (95% CI: 1.02, 1.75); (95% CI: 1.05, 2.11); (95% CI: 1.13, 2.65)]. Log-transformed PFOA, PFOS, PFNA. and PFHxS levels were negatively associated with self-reported history of menorrhagia [ (95% CI: 0.21, 0.65); (95% CI: 0.37, 0.90); (95% CI: 0.26, 0.86); (95% CI: 0.06, 0.36)].

CONCLUSIONS: Certain PFASs are associated with abnormal menstruation in humans. https://doi.org/10.1289/EHP1203.

Technical Report
Technical Report

Perfluorinated chemicals (PFCs) fact sheet

Author: NIEHS (2016) HERO ID: 3859969


Technical Report
Technical Report

Biomonitoring California. Priority chemicals. December 2015

Author: CDPH (2015) HERO ID: 3859897


Technical Report
Technical Report

Biomonitoring California. Designated chemicals. October 2015

Author: CDPH (2015) HERO ID: 3859911


Technical Report
Technical Report

Draft toxicological profile for perfluoroalkyls

Author: ATSDR (2015) HERO ID: 3859918