Health & Environmental Research Online (HERO)


Per- and Polyfluoroalkyl Substances (PFAS)


15 References Were Found:

Technical Report
Technical Report

Safety data sheet. Version 5.2. Undecafluorohexanoic acid. Product number 29226. CAS-No 307-24-4

Author: Sigma-Aldrich (2017) [Fact Sheet] HERO ID: 3980883


Technical Report
Technical Report

Environment tier II assessment for short-chain perfluorocarboxylic acids and their direct precursors. CAS registry numbers: 307-24-4, 21615-47-4, 2706-90-3, 68259-11-0, 375-22-4, 336-59-4

Author: NICNAS (2017) Australian Government Department of Health, National Industrial Chemicals Notification and Assessment Scheme. HERO ID: 3860584


Technical Report
Technical Report

Human health tier II assessment for short chain perfluorocarboxylic acids and their direct precursors

Author: NICNAS (2017) Australian Government, Department of Health, National Industrial Chemicals Notification and Assessment Scheme. HERO ID: 3860585


Technical Report
Technical Report

Case study from SEURAT-1: Perfluoroalkyl acids: direct acting toxicant category supported by SEURAT-1 data

Author: ECHA (2017) HERO ID: 3878517


Data/Software
Data/ Software

Toxicokinetic evaluation (C20613) of perfluorohexanoic acid (307-24-4) in Harlan Sprague-Dawley rats exposed via gavage or intravenous injection

Author: NTP (2017) HERO ID: 3899973


Archival Material
Archival Material

ChemSpider: Perfluorohexanoic acid (CAS Number 307-24-4)

Author: RSC (2015) Available online at http://www.chemspider.com/Chemical-Structure.60864.html. (Aug 6, 2017). [Website] HERO ID: 3980884


Technical Report
Technical Report

Response to comments document (RCOM) on the Annex XV dossier proposing restrictions on perfluorooctanoic acid (PFOA), its salts and PFOA-related substances

Author: ECHA (2015) European Chemicals Agency. HERO ID: 3898087


Technical Report
Technical Report

Draft toxicological profile for perfluoroalkyls

Author: ATSDR (2015) HERO ID: 3859918


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Serum polyfluoroalkyl concentrations, asthma outcomes, and immunological markers in a case-control study of Taiwanese children

Authors: Dong, GH; Tung, KY; Tsai, CH; Liu, MM; Wang, D; Liu, W; Jin, YH; Hsieh, WS; Lee, YL; Chen, PC (2013) Environmental Health Perspectives 121:507-13, 513e1-8. HERO ID: 1937230

[Less] BACKGROUND: Perfluorinated compounds (PFCs) are ubiquitous pollutants. Experimental . . . [More] BACKGROUND: Perfluorinated compounds (PFCs) are ubiquitous pollutants. Experimental data suggest that they may be associated with adverse health outcomes, including asthma. However, there is little supporting epidemiological evidence.

METHODS: A total of 231 asthmatic children and 225 nonasthmatic controls, all from northern Taiwan, were recruited in the Genetic and Biomarkers study for Childhood Asthma. Structure questionnaires were administered by face-to-face interview. Serum concentrations of 11 PFCs and levels of immunological markers were also measured. Associations of PFC quartiles with concentrations of immunological markers and asthma outcomes were estimated using multivariable regression models.

RESULTS: Nine PFCs were detectable in most children (≥ 84.4%), of which perfluorooctane sulfonate (PFOS) was the most abundant (median serum concentrations of 33.9 ng/mL in asthmatics and 28.9 ng/mL in controls). Adjusted odds ratios for asthma among those with the highest versus lowest quartile of PFC exposure ranged from 1.81 (95% CI: 1.02, 3.23) for the perfluorododecanoic acid (PFDoA) to 4.05 (95% CI: 2.21, 7.42) for perfluorooctanic acid (PFOA). PFOS, PFOA, and subsets of the other PFCs were positively associated with serum IgE concentrations, absolute eosinophil counts (AEC), eosinophilic cationic protein (ECP) concentrations, and asthma severity scores among asthmatics.

CONCLUSIONS: This study suggests an association between PFC exposure and juvenile asthma. Because of widespread exposure to these chemicals, these findings may be of potential public health concern.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Ambient temperature vapor pressure and adsorption capacity for (perfluorooctyl) ethylene, 3-(perfluorobutyl)propanol, perfluorohexanoic acid, ethyl perfluorooctanoate, and perfluoro-3,6-dioxaheptanoic acid

Authors: Schindler, BJ; Buchanan, JH; Mahle, JJ; Peterson, GW; Glover, TG (2013) Journal of Chemical and Engineering Data 58:1806-1812. HERO ID: 3859926

[Less] With increased use of highly fluorinated compounds has come an increased need for knowledge of the fundamental . . . [More] With increased use of highly fluorinated compounds has come an increased need for knowledge of the fundamental properties of these chemicals, such as vapor pressure, to determine how they will behave in the environment and how to remove them. A modified vapor saturation method was used to measure the ambient temperature vapor pressure of 3-(perfluorobutyl)propanol, (perfluorooctyl)ethylene, perfluorohexanoic acid, ethyl perfluorooctanoate, and perfluoro-3,6-dioxaheptanoic acid between (254.15 and 309.15) K. The freezing point for perfluorohexanoic acid was determined to be between (291.15 and 293.15) K The vapor pressures, which ranged from (0.87 to 978) Pa, were used to generate saturated vapor streams of the compound so that adsorption capacities on BPL activated carbon could be determined. Adsorption equilibrium data for three of the chemicals, measured at a feed concentration of 139 mu L.L-1 at high and low relative humidity, are presented and discussed.