Health & Environmental Research Online (HERO)


PFBS (375-73-5)


572 References Were Found:

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Multiresidue analytical method for the determination of 41 multiclass organic pollutants in mussel and fish tissues and biofluids by liquid chromatography coupled to tandem mass spectrometry

Authors: Mijangos, L; Ziarrusta, H; Zabaleta, I; Usobiaga, A; Olivares, M; Zuloaga, O; Etxebarria, N; Prieto, A (2019) Analytical and Bioanalytical Chemistry 411:493-506. HERO ID: 5097891

[Less] In this work, the full optimisation and validation procedure to analyse a wide set of emerging organic . . . [More] In this work, the full optimisation and validation procedure to analyse a wide set of emerging organic contaminants in biotissues (mussel and fish muscle, liver, gills and brain) and biofluids (fish plasma and bile) is described. The target families include artificial sweeteners, industrial products, hormones, pharmaceutical and personal care products, pesticides and phytoestrogens. Different clean-up strategies (hydrophilic-lipophilic-balanced (HLB) solid-phase extraction, Florisil solid-phase extraction and liquid-liquid extraction followed by HLB solid-phase extraction and microextraction based on polyethersulfone polymer) were evaluated for the clean-up of focused ultrasonic solid-liquid extraction (FUSLE) extracts before the analysis by liquid chromatography-triple quadrupole tandem mass spectrometry (LC-QqQ-MS/MS). The methods afforded satisfactory apparent recovery values (71-126%) using isotopically labelled analytes and matrix-matched calibration approach, regardless of the matrix. Method detection limits in the range of 4-48 ng/g and 0.3-111 ng/L were obtained for biotissues and biofluids, respectively. The developed method was applied to determine the uptake and tissue distribution in juvenile gilt-head bream (Sparus aurata) during 7 days in seawater, and unexpectedly, perfluoro-1-butanesulfonate tended to accumulate in liver and, to a lesser extent, in muscle and gills. Furthermore, real mussel samples collected in the Basque coast were also analysed and the presence of the highly consumed valsartan (7 ng/g) and telmisartan (6.8 ng/g) compounds in bivalves is reported for the first time here. Graphical abstract ᅟ.

Technical Report
Technical Report

NTP technical report on the toxicity studies of perfluoroalkyl sulfonates (perfluorobutane sulfonic acid, perfluorohexane sulfonate potassium salt, and perfluorooctane sulfonic acid) administered by gavage to Sprague Dawley (Hsd:Sprague Dawley SD) rats

Author: NTP (2019) (Toxicity Report 96). Research Triangle Park, NC: National Toxicology Program. HERO ID: 5400978


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Calibration and application of passive sampling for per- and polyfluoroalkyl substances in a drinking water treatment plant

Authors: Gobelius, L; Persson, C; Wiberg, K; Ahrens, L (2019) HERO ID: 5083652

[Less] The aim of this study was to calibrate and apply polar organic chemical integrative samplers (POCIS) . . . [More] The aim of this study was to calibrate and apply polar organic chemical integrative samplers (POCIS) to examine 26 per- and polyfluoroalkyl substances (PFASs) in a drinking water treatment plant (DWTP). As a first step, the sampling rates (Rs) of 14 PFASs were determined in a laboratory calibration study for POCIS-WAX (weak-anion exchange) and POCIS-HLB (hydrophilic-lipophilic balance) (each with a surface area per mass of sorbent ratio of 227 cm2 g-1). While most PFASs were still in the linear uptake phase during the 28-day calibration study, Rs ranged from 0.003 to 0.10 L d-1 for POCIS-WAX and 0.00052 to 0.13 for POCIS-HLB. It is important to note that POCIS-WAX had higher Rs for short-chain perfluoroalkyl carboxylates (PFCAs) with a perfluorocarbon chain length of C3-C6 and perfluorobutane sulfonate (PFBS) compared with POCIS-HLB. Furthermore, Rs was significantly positively correlated with the sorbent-water partition coefficient (Kpw) for POCIS-WAX and POCIS-HLB (p < 0.0001). Use of POCIS-WAX and POCIS-HLB in the DWTP showed good agreement with composite water sampling. No removal of PFASs was observed in the full-scale DWTP. Overall, this is the first study of PFAS monitoring in a DWTP using two types of POCIS. The results demonstrate high suitability for future applications.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Perfluorobutane Sulfonate (PFBS) Exposure Interrupts Human Cytotrophoblast Cell Proliferation and Invasion through Disruption of Focal Adhesions

Authors: Song, J; Marinello, W; Huang, R; Zhang, JunJ; Feng, L (2019) Reproductive Sciences 26:171A-171A. [Abstract] HERO ID: 5097893


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Perfluorobutanesulfonic Acid Disrupts Pancreatic Organogenesis and Regulation of Lipid Metabolism in the Zebrafish, Danio rerio

Authors: Sant, KE; Venezia, OL; Sinno, PP; Timme-Laragy, AR (2019) Toxicological Sciences 167:258-268. HERO ID: 5079849

[Less] Following the phase-out of highly persistent perfluorosulfonates in the United States from non-stick . . . [More] Following the phase-out of highly persistent perfluorosulfonates in the United States from non-stick and stain-resistant products in the early 2000s, perfluorobutanesulfonic acid (PFBS) has replaced these compounds as a primary surfactant. Measurements of PFBS in environmental and human samples have been rising in recent years, raising concerns about potential negative health effects. We previously found that embryonic exposures to a related compound, perfluorooctanesulfonic acid (PFOS), decreased pancreas length and insulin-producing islet area in zebrafish embryos (Danio rerio). The objective of this study was to compare the effects of PFBS exposures on pancreatic organogenesis with our previous PFOS findings. Dechorionated zebrafish embryos from two different transgenic fish lines (Tg[insulin:GFP], Tg[ptf1a:GFP]) were exposed to 0 (0.01% DMSO), 16, or 32 µM PFBS daily beginning at 1 day post fertilization (dpf) until 4 and 7 dpf when they were examined using fluorescent microscopy for islet area and morphology, and exocrine pancreas length. PFBS-exposed embryos had significantly increased caudal fin deformities, delayed swim bladder inflation, and impaired yolk utilization. Incidence of fish with significantly stunted growth and truncated exocrine pancreas length was significantly increased, although these two effects occurred independently. Islet morphology revealed an increased incidence of severely hypomorphic islets (areas lower than the 1st percentile of controls) and an elevated occurrence of fragmented islets. RNA-Seq data (4 dpf) also identify disruptions in regulation of lipid homeostasis. Overall, this work demonstrates that PFBS exposure can perturb embryonic development, energy homeostasis, and pancreatic organogenesis.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Perfluoroalkyl substances in groundwater and home-produced vegetables and eggs around a fluorochemical industrial park in China

Authors: Bao, J; Yu, WJ; Liu, Y; Wang, X; Jin, YH; Dong, GH (2019) Ecotoxicology and Environmental Safety 171:199-205. HERO ID: 5080600

[Less] High-level contaminations of perfluoroalkyl substances (PFASs) were determined in both surface water . . . [More] High-level contaminations of perfluoroalkyl substances (PFASs) were determined in both surface water and groundwater around a fluorochemical industrial park (FIP) in Fuxin, China, over the past few years. Yet little is known about whether groundwater PFAS contaminations in Fuxin could be introduced into home-produced vegetables and eggs in local residences via the application of groundwater for the irrigation or feeding purposes. In the present study, ten PFAS analytes were analyzed via high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) to investigate the extent of PFAS contaminations in the groundwater, soil, and home-produced vegetable and egg samples derived from Fuxin. As the predominant PFAS contaminants, perfluorobutane sulfonate (PFBS) and perfluorooctanoic acid (PFOA) were observed in groundwater beneath the Fuxin FIP with the maximum concentrations of 21.2 and 2.51 µg/L, respectively, which were 24-fold and 5-fold higher individually compared to those reported previously. Both of them were also higher than the updated health advisories for PFBS and PFOA in drinking water issued by the Minnesota Department of Health and the US Environmental Protection Agency. In addition, short-chain PFASs involving perfluorobutanoic acid (PFBA) and PFBS were found to be the major contaminants in both home-produced vegetables and eggs from the residential gardens around the FIP. Statistically significant relationships were determined between the levels of PFBA, PFOA, and PFBS in local groundwater and those observed in home-produced vegetables (p = 0.003, p = 0.025, and p < 0.001), suggesting potential entry of those PFAS contaminants into home-produced vegetables via irrigation with groundwater beneath the FIP.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Comprehensive analysis of photoinitiators and primary aromatic amines in food contact materials using liquid chromatography High-Resolution Mass Spectrometry

Authors: Sanchis, Y; Coscollà, C; Yusà, V (2019) Talanta 191:109-118. HERO ID: 5080281

[Less] A comprehensive strategy for the analysis of UV-ink photoinitiators and primary aromatic amines (PAAS) . . . [More] A comprehensive strategy for the analysis of UV-ink photoinitiators and primary aromatic amines (PAAS) in food-packaging materials such as, juice tetrabricks, pouches and bags has been developed using liquid chromatography coupled to Orbitrap High-Resolution Mass Spectrometry (LC-Orbitrap-HRMS). The methodology includes both quantitative target analysis and post-run target screening analysis. The quantitative method was validated after a previous optimisation of the single-stage Orbitrap fragmentation through the Higher-Energy Collisional Dissociation (HCD) Cell. Overall, the quantitative method presented recoveries ranging from 78% to 119%, with a precision (RSD) lower than 20%, for the 18 substances in the scope of the target method. Limit of quantification (LOQ) for UV-inks photoinitiators ranged from 0.5 µg/kg-1 for Isopropyl Thioxanthone (ITX) and 2-Ethylhexyl 4-(dimethylamino) benzoate (EHDAB) to 5 µg/kg-1 for the rest of photoinitiators. LOQ for PAAs were 2 µg/kg-1 except for aniline (ANL) and 3,3' dimethylbenzidine (3,3'-DMB) which was 2.5 µg/kg-1 in the two studied simulants (acetic acid 3% and ethanol 50%). For post-run target screening a customized theoretical database, that included Bisphenols, Polyfluorinated compounds (PFCs), Phosphorus Flame Retardants (PFRs) and other substances was built. For identification purposes, a mass accuracy lower than 5 ppm, and some diagnostic ions including isotopes and/or fragments were used. The strategy was applied to 18 samples collected in the Valencian region (Spain). No compounds were detected when the standardised migration test was applied. However, in the destructive test, benzophenone and EHDAB were determined from tetrabrick and pouch materials. In the post-run target analysis two PFCs (Perfluorooctanoic acid and Perfluoro-1-butanesulfonate) and four PFRs (2-ethylhexyl diphenyl phosphate, tris(2-choloroisopropyl) phosphate, triphenyl phosphate and 2-ethylhexyl diphenyl phosphate) were identified.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Breakdown Products from Perfluorinated Alkyl Substances (PFAS) Degradation in a Plasma-Based Water Treatment Process

Authors: Singh, RK; Fernando, S; Baygi, SF; Multari, N; Thagard, SM; Holsen, TM (2019) Environmental Science and Technology 53:2731-2738. HERO ID: 5080314

[Less] Byproducts produced when treating perfluorooctanoic acid (PFOA) and perfluorooctanesulfonate (PFOS) . . . [More] Byproducts produced when treating perfluorooctanoic acid (PFOA) and perfluorooctanesulfonate (PFOS) in water using a plasma treatment process intentionally operated to treat these compounds slowly to allow for byproduct accumulation were quantified. Several linear chain perfluoroalkyl carboxylic acids (PFCAs) (C4 to C7) were identified as byproducts of both PFOA and PFOS treatment. PFOA, perfluorohexanesulfonate (PFHxS), and perfluorobutanesulfonate (PFBS) were also found to be byproducts from PFOS degradation. Significant concentrations of fluoride ions, inorganic carbon, and smaller organic acids (trifluoroacetic acid, acetic acid, and formic acid) were also identified. In addition to PFCAs, PFHxS, and PFBS, trace amounts of 43 PFOA-related and 35 PFOS-related byproducts were also identified using a screening and search-based algorithm. Minor concentrations of gas-phase byproducts were also identified (<2.5% of the F originally associated with the parent molecules) some of which are reported for the first time in perfluoroalkyl substance degradation experiments including cyclic perfluoroalkanes (C4F8, C5F10, C6F12, C7F14, and C8F16). The short chain PFCAs detected suggest the occurrence of a stepwise reduction of the parent perfluoroalkyl substances (PFAS) molecule, followed by oxidation of intermediates, perfluoroalkyl radicals, and perfluoro alcohols/ketones. Using a fluorine mass balance, 77% of the fluorine associated with the parent PFOA and 58% of the fluorine associated with the parent PFOS were identified. The bulk of the remaining fluorine was determined to be sorbed to reactor walls and tubing using sorption experiments in which plasma was not generated.

Journal Article
Journal Article

Highly Defective UiO-66 Materials for the Adsorptive Removal of Perfluorooctanesulfonate

Authors: Clark, CA; Heck, KN; Powell, CD; Wong, MS (2019) 7:6619-6628. HERO ID: 5097896


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Characterization of perfluoroalkyl substances in sediment cores from High and Low Arctic lakes in Canada

Authors: Macinnis, JJ; Lehnherr, I; Muir, DCG; Quinlan, R; De Silva, AO (2019) Science of the Total Environment 666:414-422. HERO ID: 5024202

[Less] Perfluoroalkyl substances (PFASs) are synthetic environmentally-persistent pollutants that are amenable . . . [More] Perfluoroalkyl substances (PFASs) are synthetic environmentally-persistent pollutants that are amenable to long-range transport and accumulation in remote Arctic ecosystems. In this study, historical inventories of twenty-three PFASs (i.e. C4-C14, C16 perfluoroalkane carboxylic acids (PFCAs); C4, C6-C8, C10 perfluoroalkane sulfonic acids (PFSAs); perfluoro-4-ethyl-cyclohexane sulfonic acid (PFECHS); dodecafluoro-3H-4,8-dioxanonanoic acid (ADONA); 8-chloro-perfluoro-1-octane sulfonic acid (8-Cl-PFOS); chlorinated polyfluorinated ether sulfonic acids (Cl-PFESAs) including 9-chlorohexadecafluoro-3-oxanonane-1-sulfonic acid (6:2 Cl-PFESA) and 11-chloroeicosafluoro-3-oxaundecane-1-sulfonic acid (8:2 Cl-PFESA); as well as perfluorooctane sulfonamide (FOSA)) are determined in two intact sediment cores collected from Lake Hazen, located in northern Ellesmere Island at 82° N in 2012 and Lake B35, located in central Nunavut at 64° N in 2009. In Lake Hazen, fluxes of perfluorooctanoic acid (PFOA), perfluorodecanoic acid (PFDA), perfluorobutane sulfonic acid (PFBS), and perfluorooctane sulfonic acid (PFOS) increased during 1963-2011. In Lake B35, fluxes of perfluoroheptanoic acid (PFHpA), PFOA, perfluorononanoic acid (PFNA), and perfluoroundecanoic acid (PFUnDA) increased during 1952-2009. The temporal trends for PFASs in Lake Hazen and Lake B35 sediments are consistent with the continuous annual delivery of PFASs to the Arctic of Canada. Temporal trends in sediment cores appear to follow historical market changes in PFAS manufacturing inventory. The doubling time of PFAS fluxes are faster in Lake Hazen sediments than Lake B35 sediments. In Lake Hazen, this may be attributed to the enhanced delivery of sediment and historically-archived PFASs promoted by climate-induced glacier melting in the Lake Hazen watershed post-2005. Exponentially increasing PFAS temporal trends in High and Low Arctic lakes in Canada stress the importance of developing effective global regulatory policies for PFAS manufacturing and highlights the potential for climate change-induced contaminant release from melting glaciers in the Arctic.