Health & Environmental Research Online (HERO)


PFDoA (307-55-1)


194 References Were Found:

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Removal efficiency of multiple poly- and perfluoroalkyl substances (PFASs) in drinking water using granular activated carbon (GAC) and anion exchange (AE) column tests

Authors: Mccleaf, P; Englund, S; Östlund, A; Lindegren, K; Wiberg, K; Ahrens, L (2017) Water Research 120:77-87. HERO ID: 3856453

[Less] Poly- and perfluoroalkyl substances (PFASs) have been detected in drinking water at relatively high . . . [More] Poly- and perfluoroalkyl substances (PFASs) have been detected in drinking water at relatively high concentrations throughout the world which has led to implementation of regulatory guidelines for specific PFASs in drinking water in several European countries and in the U.S. The Swedish National Food Agency has determined that the drinking water of over one third of the country's municipal consumers is at risk or already affected by PFAS contamination. The present study investigated the effects of perfluorocarbon chain length, functional group and isomer structure (branched or linear) on removal of multiple PFASs using granular activated carbon (GAC, Filtrasorb(®) 400) and anion exchange (AE, Purolite(®) A600) column experiments. The removal of 14 different PFASs, i.e. the C3C11, C14 perfluoroalkyl carboxylic acids (PFCAs) (PFBA, PFPeA, PFHxA, PFHpA, PFOA, PFNA, PFDA, PFUnDA, PFDoDA, PFTeDA), perfluorooctane sulfonamide (FOSA), and the C4, C6, C8 perfluoroalkyl sulfonic acids (PFSAs) (PFBS, PFHxS, PFOS), was monitored for a 217 day period. The results indicate the selective nature of PFAS removal as the absorbents are loaded with PFASs and dissolved organic carbon (DOC). A clear relationship between perfluorocarbon chain length and removal efficiency of PFASs using GAC and AE was found while PFASs with sulfonate functional groups displayed greater removal efficiency than those with carboxylate groups. Similarly, time to column breakthrough increased with increasing perfluorocarbon chain length and was greater for the PFSAs than the PFCAs for both GAC and AE. Shorter carbon chained PFASs such as PFBA, PFPeA, PFHxA showed desorption behavior and long-chained PFASs showed increased removal towards the end of the experiment indicating agglomeration or micelle development. Linear isomers of PFOS, PFHxS, and perfluorooctane sulfonamide (FOSA) had greater column removal efficiencies using GAC (and also for AE at greater bed volume throughput) than the branched and this difference increased at greater bed volume throughputs. The GAC and AE columns showed a poor correlation between DOC and PFAS removal efficiency. The results indicate that designers and operators of AE and GAC treatment processes must take into consideration the selective nature of PFAS removal and associated desorption of short-chain PFCAs during co-removal of multiple PFASs.

Technical Report
Technical Report

Human health tier II assessment for indirect precursors of long-chain perfluorocarboxylic acids (PFCAs)

Author: NICNAS (2017) Australian Government, Department of Health, National Industrial Chemicals Notification and Assessment Scheme. HERO ID: 3874962


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Perfluorododecanoic acid induces cognitive deficit in adult rats

Authors: Kawabata, K; Matsuzaki, H; Nukui, S; Okazaki, M; Sakai, A; Kawashima, Y; Kudo, N (2017) Toxicological Sciences 157:421-428. HERO ID: 3858489

[Less] The brain level of perfluorododecanoic acid (PFDoA) was compared with those of perfluorooctanoic acid . . . [More] The brain level of perfluorododecanoic acid (PFDoA) was compared with those of perfluorooctanoic acid (PFOA) and perfluorodecanoic acid (PFDA) in rats 9 days after a single oral dose (50 mg/kg). The PFDoA level in the brain was 44.0 ± 2.0 µg/g, which was higher than that in the serum (24.4 ± 1.0 µg/ml). In contrast, the concentrations of PFOA and PFDA in the brain were low (<0.8 and 4.7 ± 0.4 µg/g, respectively), and less than one-tenth of those in the serum. Next, to investigate the effects on brain function, the cognitive function alterations of PFOA, PFDA, and PFDoA were estimated by the novel object recognition test 5-6 days after dosing. A significant decrease in the discrimination index was observed in PFDoA-treated rats while no significant alteration was observed in PFDA- and PFOA-treated rats. The effects of PFDoA were further assessed by other behavioral tests. PFDoA-associated alteration was observed in the elevated-plus maze test, but not in the Y-maze test, open-field test, and forced swim test. A decrease in the discrimination index of the novel object recognition test was dependent on the PFDoA dose and the PFDoA concentration in the brain. PFDoA concentration in the brain was 28.6 ± 2.6 µg/g 30 days after dosing, and a decrease in discrimination index was observed. Taken together, these results suggest that PFDoA distributes in the brain easier than PFOA and PFDA and causes cognitive deficit.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

The measurement of bisphenol A and its analogues, perfluorinated compounds in twenty species of freshwater and marine fishes, a time-trend comparison and human health based assessment

Authors: Wong, YM; Li, R; Lee, CKF; Wan, HT; Wong, CKC (2017) Marine Pollution Bulletin 124:743-752. HERO ID: 3858481

[Less] Our previous study in 2011 reported the detection of BPA and PFAAs in 20 species of marine and freshwater . . . [More] Our previous study in 2011 reported the detection of BPA and PFAAs in 20 species of marine and freshwater fishes. With an emerging evidence to suggest the metabolic-disrupting effects of BPA/PFAAs in animals, the present study was aimed to provide a time-trend analysis to determine the current concentrations of PFAAs and BPA in 20 commercially available Hong Kong species of fishes. Since the manufacture and use of BPA is being prohibited in most nations, the introduction of BPA alternatives has recently been incorporated in the markets. Therefore, the concentrations of BPB, BPF and BPS were determined. In the present study, all freshwater and seawater fish samples showed quantified concentrations [>Limit of Quantification (LOQ<0.5ng/g)] of BPA. BPF was detected in some marine (yellow seafin, bigeye, goldspotted rabbitfish, snubnose pompano, tongue sole, Bleeker's grouper and orange-spotted grouper) and freshwater fishes (mud carp, crucian carp, tilapia, catfish, mandarin fish, grass carp, grey mullet and spotted snakehead). Two of the compounds, BPS and BPB could only be identified in the marine fishes (snubnose pompano, yellow seafin). In PFAA analysis, PFOA, PFDA, PFOS, PFUdA and PFDoA were found in most of the marine and freshwater fishes. PFOS and PFOA were shown to be the two predominant PFAAs in fishes. On the basis of the measured concentrations of bisphenols, BPs (BPA, BPB, BPF, BPS) and PFAAs, the average daily intake for BPs (20.5-31.5ng/kgb.w./day) and PFAAs (1.17-1.83ng/kgb.w./day) were calculated and found to be lower than values of tolerable daily intake (TDI) established in Europe. However, as compared with our previous study in 2011, the present study revealed an approximate 10-fold increase in the concentrations of BPA in the fish samples. Although the hazard ratio of consuming fishes for BPA and PFAA exposure is expected to remain low, possible additive metabolic-disrupting effect of BPA and its analogues as well PFAAs should be taken into consideration for human health risk assessment.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Brominated flame retardants and perfluoroalkyl acids in groundwater, tile drainage, soil, and crop grain following a high application of municipal biosolids to a field

Authors: Gottschall, N; Topp, E; Edwards, M; Payne, M; Kleywegt, S; Lapen, DR (2017) Science of the Total Environment 574:1345-1359. HERO ID: 3858509

[Less] Dewatered municipal biosolids (DMB) were applied at a rate of 22Mgdwha(-1) to an agricultural field . . . [More] Dewatered municipal biosolids (DMB) were applied at a rate of 22Mgdwha(-1) to an agricultural field in fall 2008. Concentrations of polybrominated diphenyl ethers (PBDEs; BDE-47, -99, -100, -153, -154, -183, -197, -207, -209), other brominated flame retardants (BFRs; HBB, PBEB, DBDPE, BTBPE) and perfluoroalkyl acids (PFAAs; PFHxS, PFOS, PFDS, PFOSA, PFHpA, PFOA, PFNA, PFDA, PFUnA, PFDoA, PFTA) were monitored in tile drainage, groundwater (2m, 4m and 6m depth), soil cores (0-0.3m) pre- and post-application, DMB aggregates incorporated into the soil post-application, and in wheat (Triticum spp.) planted post-application. Several compounds were detected in soil and water pre-application and on a reference field plot. PBDEs, other BFRs and PFAAs were detected in tile drainage and 2m groundwater throughout the post-application study period; a few PBDEs were also detected sporadically at lower depths in groundwater. Some of these compounds had not been detected pre-application, while some exceeded reference field plot/pre-application levels (some significantly (p<0.05) in tile drainage); both cases indicating biosolid-based water contamination. In DMB aggregates, several PBDE congeners were found to have dissipated exponentially, with reductions >90% in many of them within 1year post-application. Exponential dissipation of other BFRs and PFAAs in DMB aggregates were not significant. No PBDEs, other BFRs, or PFAAs were detected in wheat grain.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Hyperporphyrin effect on oxygen sensitivity of free meso-tetraphenylporphyrins

Authors: Topal, SZ; Ongun, MZ; Onal, E; Ertekin, K; Hirel, C (2017) HERO ID: 3859537

[Less] A series of dyes; three symmetric free meso-tetraphenylporphyrins, bearing phenylacetylide (H2-TPA), . . . [More] A series of dyes; three symmetric free meso-tetraphenylporphyrins, bearing phenylacetylide (H2-TPA), hexyloxy (H2-OHex) or without peripheral substituent (H2-TPP) were chosen as luminophore to explore the effect of meso-substitution on the oxygen sensing ability. These dyes were incorporated into poly(trimethylsilylpropyne) [poly(TMSP)], polymethylmethacrylate (PMMA) and silicone matrices along with additives such as perfluorododecanoic acid (PFC) to improve the oxygen sensitivity as well as ionic liquid to favor the microfiber preparation by electrospinning. The pH of the medium is affected by the composition of the cocktail, a non-trivial effect which induce protonation of the free meso-tetraphenylporphyrin derivatives bearing electron donor (H2-OHex) and withdrawing substituents (H2-TPA), which results in absorbance and emission spectroscopic modifications called elsewhere hyperporphyrin effect. Spectrophotometric titrations were carried out by using HClO4 in THE solution and PFC in [poly(TMSP)]-based thin film to study the hyperporphyrin effect of H2-TPA, H2-OHex and H2-TPP showing the influence of the substituent bn the pKa of the inner nitrogen's. The ratio of PFC/dyes optimization was prospected and the influence of the pH/protonation on the steady-state oxygen sensitivity was studied. (C) 2017 Elsevier Ltd. All rights reserved.

Technical Report
Technical Report

Perfluorododecanoic acid ( 307-55-1 ). Combined repeated dose toxicity study with the reproduction/developmental toxicity screening test (in Japanese). Japan Existing Chemicals Database.

Author: CIPCJ (2017) HERO ID: 3862191


Technical Report
Technical Report

Perfluorododecanoic acid (307-55-1 ). Bacterial reverse mutation test (in Japanese). Japan Existing Chemical Data Base (JECDB)

Author: CIPCJ (2017) HERO ID: 3862262


Technical Report
Technical Report

Perfluorododecanoic acid (307-55-1). In vitro mammalian chromosome aberration test (in Japanese). Japan Existing Chemical Data Base(JECDB)

Author: CIPCJ (2017) HERO ID: 3862317


Technical Report
Technical Report

Safety data sheet. Version 4.5. Tricosafluorododecanoic acid. Product number 406449. CAS-No. 307-55-1

Author: Sigma-Aldrich (2017) HERO ID: 3980877