Health & Environmental Research Online (HERO)


PFHxS (355-46-4)


112 References Were Found:

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Image-based reconstruction for a 3D-PFHS heat transfer problem by ReConNN

Authors: Li, Yu; Wang, Hu; Deng, X (2019) HERO ID: 5097919


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Constructal operation cost minimization for in-line cylindrical pin-fin heat sinks

Authors: Yang, A; Chen, L; Xie, Z; Feng, H; Sun, F (2019) HERO ID: 5097917


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Factors associated with exposure of pregnant women to perfluoroalkyl acids in North China and health risk assessment

Authors: Yang, J; Wang, H; Du, H; Xu, L; Liu, S; Yi, J; Qian, X; Chen, Y; Jiang, Q; He, G (2019) Science of the Total Environment 655:356-362. HERO ID: 5080660

[Less] Perfluoroalkyl acids (PFAAs) have been frequently found in blood of pregnant women, but the predictors . . . [More] Perfluoroalkyl acids (PFAAs) have been frequently found in blood of pregnant women, but the predictors and potential health risk have not been well studied in China. We recruited 534 pregnant women in Tangshan City of Hebei Province in North China between 2013 and 2014 and measured five PFAAs in serum during their early term of pregnancy, including perfluorooctanoic acid (PFOA), perfluorooctane sulfonic acid (PFOS), perfluorohexane sulfonic acid (PFHxS), perfluoro‑n‑undecanoic acid (PFUdA), and perfluorononanoic acid (PFNA). We explored the factors associated with the levels of serum PFAAs and assessed associated health risks. Food consumption information was obtained by food frequency questionnaire covering 100 items. Multiple linear regression model was used to determine the associations of sociodemographic, anthropometric, and food factors with the concentrations of serum PFAAs. Some PFAAs in serum were positively associated with age and body mass index (BMI). Consumption of beans, aquatic products, and eggs was positively associated with the concentrations of several PFAAs after adjusting for important covariates. Pregnant women who ate more cereal, vegetables, mushrooms and alga tended to have lower levels of serum PFOA, PFOS and PFNA. The Hazard index (HI) for reproductive toxicity and developmental toxicity was below 0.8, and the HI for hepatotoxicity beyond 1 was found in 0.37% of pregnant women. These results suggested that age, BMI, and some food consumption were predictors for the exposure to PFAAs in Chinese pregnant women. More attention should be paid to the hepatotoxicity for these exposures.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Occurrence and characteristics of perfluoroalkyl substances (PFASs) in electroplating industrial wastewater

Authors: Jiawei, T; Yizhen, Z; Jiajun, S; Xuelu, S; Chao, S; Chunhui, Z (2019) Water, Science and Technology 79:731-740. HERO ID: 5081333

[Less] The potential negative effects of perfluoroalkyl substances (PFASs) discharged into aquatic environments . . . [More] The potential negative effects of perfluoroalkyl substances (PFASs) discharged into aquatic environments are drawing increasing attention. However, little research has been undertaken on PFASs in wastewater from electroplating industrial parks. In this study, the concentration profiles and geographical distribution of 11 PFASs were analyzed in water samples collected from different production workshops and an artificial landscaped lake. The total concentrations of PFASs (Σ11PFASs) at various points in the production drainage system range from 229.5 to 5410.6 ng/L, and are mainly contributed by nickel plating, pickling, and the cyanide bright silver plating procedure, which correspond to cyanide-containing and acid-alkali wastewater conditioning tanks. Wastewater treatment by oxidation and precipitation removed 52.6% and 20% of PFASs, respectively. Σ11PFASs in effluents is about 538 ng/L, which consists of perfluorooctanoic acid (PFOA, 430.5 ng/L), followed by perfluorooctane sulfonate (PFOS, 35.27 ng/L), perfluorohexane sulfonate (PFHxS, 28.05 ng/L), and perfluorohexanoic acid (PFHxA, 18.3 ng/L). Principal component analysis suggests that the Σ11PFASs in electroplating wastewater is very high and short-chain (C4-C8) PFASs have high detection and contribution rates. As a result, much attention should be paid to the increase in short-chain substitution effects and pollution around the factory area.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Does water temperature influence the distribution and elimination of perfluorinated substances in rainbow trout (Oncorhynchus mykiss)?

Authors: Vidal, A; Lafay, F; Daniele, G; Vulliet, E; Rochard, E; Garric, J; Babut, M (2019) Environmental Science and Pollution Research 26:16355-16365. HERO ID: 5081331

[Less] Perfluorinated and polyfluorinated substances (PFASs) are widely found in freshwater ecosystems because . . . [More] Perfluorinated and polyfluorinated substances (PFASs) are widely found in freshwater ecosystems because of their resistance to degradation and their ability to accumulate in aquatic organisms. While water temperature controls many physiological processes in fish, knowledge of the effects of this factor on PFAS toxicokinetic is still limited. This study presents experimental results of internal distribution and elimination rates of two perfluorinated acid compounds, namely perfluorooctane sulfonate (PFOS) and perfluorohexane sulfonate (PFHxS) in adult rainbow trout (Oncorhynchus mykiss) exposed to three temperatures. Dietary exposure experiments were conducted at 7 °C, 11 °C, and 19 °C and liver, blood, muscle, brain, and kidney were sampled for analysis. PFOS concentrations were comparable to or exceeded those of PFHxS, while PFHxS was eliminated faster than PFOS, whatever the temperature. Internal distribution changed significantly for both substances when fish were exposed to a range of temperatures from 7 to 19 °C. Indeed, PFOS and PFHxS relative distribution increased in blood, liver, and brain while they decreased in muscle when the water temperature rose. The water temperature variation affected the elimination half-lives, depending on the substances and organs.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Changes in Adsorption Behavior of Perfluorooctanoic Acid and Perfluorohexanesulfonic Acid Through Chemically-Facilitated Surface Modification of Granular Activated Carbon

Authors: Siriwardena, DP; Crimi, M; Holsen, TM; Bellona, C; Divine, C; Dickenson, E (2019) HERO ID: 5097909

[Less] Activated carbon is a versatile sorbent and effective contaminant removal media due to its complex porous . . . [More] Activated carbon is a versatile sorbent and effective contaminant removal media due to its complex porous structure and high surface area. The main purpose of this research is to increase the uptake of perfluoroalkyl and polyfluoroalkyl substances (PFAS) through modifications of granular activated carbon (GAC) by chemical treatment. To increase the adsorption of perfluorooctanoic acid (PFOA) and perfluorohexanesulfonic acid (PFHxS) onto GAC, the surface characteristics of two types of GAC from Calgon Carbon Corporation (charcoal-based Filtrasorb-F400 and coconut-based OLC 12 x 30-CBC) were chemically modified. Two GAC were treated with acid (hydrochloric acid [HCl]), base (sodium hydroxide [NaOH]), heat activated persulfate (PS), and hydrogen peroxide catalyzed with iron (H2O2/Fe). The extent of adsorption after 2-, 5-, and 10-day reaction time and the changes in carbon surface physical and chemical characteristics of treated GAC were compared with untreated GAC. Several characterization techniques, including Brunauer-Emmett-Teller surface area, pH of point zero charge, scanning electron microscopy with elemental analysis, and Fourier transform infrared spectroscopy, were used to analyze treated and untreated GAC. The extent of adsorption of both PFHxS and PFOA increased (7-8% in F400 and 6-9% in CBC) with HCl treatment likely due to increase in positive charge density, had no significant change with NaOH treatment, and decreased with PS (22-25% in F400 and 27-35% in CBC) and H2O2/Fe (4-8% in F400 and 12-13% in CBC) treatment. All the treated GAC had lower BET surface area compared to untreated GAC which is the main physical property deemed responsible for decreased adsorption. It was found that surface oxygen functional groups increased with treatments and decreased the hydrophobicity of the GAC surface, which resulted in lower PFAS adsorption.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Exposure to environmental pollutants and their association with biomarkers of aging: A multipollutant approach

Authors: Vriens, A; Nawrot, TS; Janssen, BG; Baeyens, W; Bruckers, L; Covaci, A; De Craemer, S; De Henauw, S; Den Hond, E; Loots, I; Nelen, V; Schettgen, T; Schoeters, G; Martens, DS; Plusquin, M (2019) Environmental Science and Technology 53:5966-5976. HERO ID: 5097913

[Less] Mitochondrial DNA (mtDNA) content and telomere length are putative aging biomarkers and are sensitive . . . [More] Mitochondrial DNA (mtDNA) content and telomere length are putative aging biomarkers and are sensitive to environmental stressors, including pollutants. Our objective was to identify, from a set of environmental exposures, which exposure is associated with leukocyte mtDNA content and telomere length in adults. This study includes 175 adults from 50 to 65 years old from the cross-sectional Flemish Environment and Health study, of whom leukocyte telomere length and mtDNA content were determined using qPCR. The levels of exposure of seven metals, 11 organohalogens, and four perfluorinated compounds (PFHxS, PFNA, PFOA, PFOS) were measured. We performed sparse partial least-squares regression analyses followed by ordinary least-squares regression to assess the multipollutant associations. While accounting for possible confounders and coexposures, we identified that urinary cadmium (6.52%, 95% confidence interval, 1.06, 12.28), serum hexachlorobenzene (2.89%, 018, 5.68), and perfluorooctanesulfonic acid (11.38%, 5.97, 17.08) exposure were positively associated ( p < 0.05) with mtDNA content, while urinary copper (-9.88%, -14.82, -4.66) and serum perfluorohexanesulfonic acid (-4.75%, -8.79, -0.54) exposure were inversely associated with mtDNA content. Urinary antimony (2.69%, 0.45, 4.99) and mercury (1.91%, 0.42, 3.43) exposure were positively associated with leukocyte telomere length, while urinary copper (-3.52%, -6.60, -0.34) and serum perfluorooctanesulfonic acid (-3.64%, -6.60, -0.60) showed an inverse association. Our findings support the hypothesis that environmental pollutants interact with molecular hallmarks of aging.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Maternal serum concentrations of perfluoroalkyl substances and birth size in British boys

Authors: Marks, KJ; Cutler, AJ; Jeddy, Z; Northstone, K; Kato, K; Hartman, TJ (2019) International Journal of Hygiene and Environmental Health 222:889-895. HERO ID: 5081319

[Less] Per- and polyfluoroalkyl substances (PFAS) have been widely used in commercial and industrial manufacturing . . . [More] Per- and polyfluoroalkyl substances (PFAS) have been widely used in commercial and industrial manufacturing processes since the 1950s. Inverse associations between prenatal exposure to PFAS and birth size have been found in populations around the globe. This study examined the association of prenatal maternal serum concentrations of perfluorooctane sulfonic acid (PFOS), perfluorooctanoic acid (PFOA), perfluorohexane sulfonic acid (PFHxS), and perfluorononanoic acid (PFNA) and birth size in British boys. The study included 457 mother-son dyads participating in the Avon Longitudinal Study of Parents and Children (ALSPAC). Birth weight (g), crown to heel length (cm), and head circumference (cm) were collected at delivery. PFAS were detected in all maternal serum samples during pregnancy (median: 30 weeks gestation (interquartile range: 12-33)). Median concentrations (interquartile range) were 13.8 ng/mL (11.0, 17.7), 3.0 ng/mL (2.3, 3.8), 1.9 ng/mL (1.4, 2.5), and 0.4 ng/mL (0.3, 0.5) for PFOS, PFOA, PFHxS, and PFNA, respectively. In multivariable linear regression models, inverse associations were detected between PFOS (continuous) and birth weight (β = -8.50 g, 95% CI = -15.93, -1.07 g), crown to heel length (β = -0.04 cm, 95% CI = -0.08, -0.01 cm), and head circumference (β = -0.02 cm, 95% CI = -0.04, -0.002 cm). In conclusion, prenatal exposure to high levels of PFOS may be associated with reduced birth size in male infants.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Length-specific occurrence and profile of perfluoroalkyl acids (PFAAs) in animal protein feeds

Authors: Li, X; Gao, K; Dong, S; Liu, X; Fu, K; Wang, P; Zhang, A; Su, X; Fu, J (2019) Journal of Hazardous Materials 373:224-231. HERO ID: 5097892

[Less] Animal protein supplement feeds (APFs) are susceptible to perfluoroalkyl acids (PFAAs) and could be . . . [More] Animal protein supplement feeds (APFs) are susceptible to perfluoroalkyl acids (PFAAs) and could be the main sources for raised animals, thereafter causing further human exposure through the farm-to-fork pathway. However, the occurrence of PFAAs has been rarely evaluated in various APFs, especially for emerging short-chain PFAAs. In the present study, we collected the most prevalent APFs (blood meal, meat meal, feather meal, soybean meal and DDGS) and found that Σ16PFAAs ranged from undetectable to 37.1 ng/g dry weight (dw) (average: 7.23 ng/g dw). Blood meal contained the highest PFAA levels, and results revealed that some terrestrial-derived APFs might be present at levels on par with the marine-derived feed. Animal-derived APFs (mean 10.9 ng/g dw) possessed higher ∑PFAAs than plant-derived APFs (0.75 ng/g dw). Length-specific PFAA profiles were specified between terrestrial-origin and marine-origin feeds in addition to animal-derived and plant-derived feeds. Short-chain PFAAs (PFBA, PFBS and PFHxS) were primarily found in blood meal, meat meal, soybean meal and DDGS, while the long-chain counterparts dominated in feather meal. It is of great concern that feed exposure to emerging contaminants has not drawn enough attention.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Levels, spatial distribution and isomer profiles of perfluoroalkyl acids in soil, groundwater and tap water around a manufactory in China

Authors: Gao, Y; Liang, Y; Gao, K; Wang, Y; Wang, C; Fu, J; Wang, Y; Jiang, G; Jiang, Y (2019) Chemosphere 227:305-314. HERO ID: 5097911

[Less] In this study, 32 surface soil samples, 24 groundwater samples, and 6 tap water samples were collected . . . [More] In this study, 32 surface soil samples, 24 groundwater samples, and 6 tap water samples were collected around a perfluorosulfonates (PFSAs) manufactory in China to analyze the distributions of perfluoroalkyl acids (PFAAs) including linear and branched isomers. The total concentrations of PFAAs (∑PFAAs) ranged from 1.30 to 913 ng/g on a dry weight basis (dw), 31.4-15656 ng/L, and 11.8-59.7 ng/L in soil, groundwater and tap water samples respectively. Perfluorooctanesulfonate (PFOS) and perfluorobutanoic acid (PFBA) were the predominant PFAAs in the soil whereas PFBA was the predominant congener in groundwater. PFAA concentrations in the soil and groundwater decreased with increasing distance from the manufactory. Shorter-chain PFAAs showed higher proportions in groundwater than in soil samples and that shorter-chain PFAAs exhibited faster decreasing rates in soil samples, which may be due to the differences in the polarity and hydrophobicity of these molecules. For isomer profiles, n-PFHxS, n-PFOS, and n-PFOA were the main isomer in soil samples and groundwater samples. Direct exposure to PFOS and PFOA via the soil and tap water posed relatively low risk to the residents' health.