Health & Environmental Research Online (HERO)


PFBA (375-22-4)


798 References Were Found:

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Synthesis and properties of partially biodegradable fluorinated polyacrylate: Poly(L-lactide)-co-poly(hexafluorobutyl acrylate) copolymer

Authors: Huang, Yun; Pan, Y; Wang, W; Jiang, L; Dan, Yi (2019) HERO ID: 5098218


Archival Material
Archival Material

EPA Actions to Address PFAS

Author: U.S. EPA (2019) Available online at https://www.epa.gov/pfas/epa-actions-address-pfas. [Website] HERO ID: 5099058


Technical Report
Technical Report

Fourth National Report on Human Exposure to Environmental Chemicals, Updated Tables, January 2019, Volume 1

Author: CDC (2019) HERO ID: 5231431


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Protein-specific distribution patterns of perfluoroalkyl acids in egg yolk and albumen samples around a fluorochemical facility

Authors: Wang, F; Zhao, C; Gao, Y; Fu, J; Gao, K; Lv, K; Wang, K; Yue, H; Lan, X; Liang, Y; Wang, Y; Jiang, G (2019) Science of the Total Environment 650:2697-2704. HERO ID: 5080187

[Less] In this study, eggs from free-range and barn chickens in farms around a fluorochemical facility were . . . [More] In this study, eggs from free-range and barn chickens in farms around a fluorochemical facility were collected to assess the distribution profiles of perfluoroalkyl acids (PFAAs), including isomers of perfluorooctane sulfonate (PFOS), perfluorooctanoic acid (PFOA), and perfluorohexane sulfonate (PFHxS), in egg yolk and albumen. The results revealed that the concentrations of PFAAs in yolks were significantly higher than those in albumen. All 17 PFAAs examined could be detected in yolks, showing decreasing concentrations with increasing distance from the fluorochemical facility. The three predominant compounds in yolks were perfluorobutanoic acid (PFBA, mean concentration 81.4 ng/g ww), PFOS (28.0 ng/g ww), and PFOA (4.83 ng/g ww), and this result is consistent with the product structure of the facility. Moreover, n-PFOA, n-PFOS, and n-PFHxS were the dominant contaminants in yolk, with mean concentrations of 4.75, 25.7, and 4.29 ng/g ww, respectively. In albumen, PFBA was still the predominant PFAA congener (mean concentration = 3.93 ng/g ww), followed by PFOA. Docking analysis indicated that the PFAAs presented higher binding abilities with the low density lipoprotein, high density lipoprotein, and vitellin proteins in yolk than that with ovalbumin albumen proteins, which might be the main factor influencing the possible difference in distributions of PFAAs in yolk and albumen.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Perfluoroalkyl acids in drinking water of China in 2017: Distribution characteristics, influencing factors and potential risks

Authors: Li, Y; Li, J; Zhang, L; Huang, Z; Liu, Y; Wu, N; He, J; Zhang, Z; Zhang, Y; Niu, Z (2019) Environment International 123:87-95. HERO ID: 5080645

[Less] Perfluoroalkyl acids (PFAAs) are a group of emerging persistent organic pollutants (POPs), which have . . . [More] Perfluoroalkyl acids (PFAAs) are a group of emerging persistent organic pollutants (POPs), which have been ubiquitously detected in the environmental media. However, national scale investigations on their occurrence and distribution in drinking water are still insufficient. In this study, we detected the 17 priority PFAAs in drinking water from 79 cities of 31 provincial-level administrative regions throughout China, and investigated their occurrence and distribution. Additionally, we also analyzed the influencing factors on their profiles, such as the existence of industrial sources, socioeconomic factors (population density and GDP), and assessed levels of risk associated with contaminated drinking water. On the national scale, the sum concentrations of the 17 PFAAs (∑17PFAAs) in drinking water was in a range of 4.49-174.93 ng/L with a mean value of 35.13 ng/L. Among the 17 individual PFAAs, perfluorobutanoic acids (PFBA) was the most abundant individual PFAAs with the median concentration of 17.87 ng/L, followed by perfluorooctanoic acid (PFOA, 0.74 ng/L), perfluorononanoic acid (PFNA, 0.40 ng/L) and perfluorooctane sulfonic acid (PFOS, 0.25 ng/L). The geographic distribution characteristic of ∑17PFAAs in drinking water was in a descending order of Southwestern China (57.67 ng/L) > Eastern coastal China (32.85 ng/L) > Middle China (29.89 ng/L) > Northwestern China (28.49 ng/L) > Northeastern China (22.03 ng/L), and in general, the existence of the industrial sources could positively affect the contamination levels of PFAAs in drinking water. The pollution level of PFAAs in drinking water also varied among the three different city levels (medium-sized city > big city > town). In towns, the positive correlations were observed between the population density and the ∑17PFAAs (R2 = 0.45, p < 0.01), and the individual concentration of PFHxA, PFBS, and PFOA (p < 0.01). Moreover, besides PFAAs in Yunnan, Jiangsu, and Jiangxi, concentrations of related PFAAs in drinking water from 28 provinces were less than the suggested drinking water advisories. The relatively higher concentrations of PFAAs in Yunnan, Jiangsu, and Jiangxi suggest that further studies focusing on their sources and potential health risk to humans are needed.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Determination of 20 perfluoroalkyl substances in greenhouse vegetables with a modified one-step pretreatment approach coupled with ultra performance liquid chromatography tandem mass spectrometry(UPLC-MS-MS)

Authors: Zhou, Y; Lian, Y; Sun, X; Fu, L; Duan, S; Shang, C; Jia, X; Wu, Y; Wang, M (2019) HERO ID: 5098207

[Less] A new rapid modified one-step QuEChERS (quick, easy, cheap, effective, rugged, and safe) approach was . . . [More] A new rapid modified one-step QuEChERS (quick, easy, cheap, effective, rugged, and safe) approach was developed for the simultaneous determination of 20 perfluoroalkyl substances (PFASs) from samples of cucumber, lettuce, eggplant, tomato, and leek. Several parameters were optimized. Similar pretreatment approaches were employed for comparison; the results verified the satisfactory performance of this new method. The detection limits of this method for the selected matrices ranged from 0.003 to 0.034 μg kg-1, and the method was verified to be satisfactory in terms of precision, accuracy, and matrix effects. 35 greenhouse vegetable samples were determined. PFASs were detected in 26 samples, with perfluorooctanoic acid (PFOA) being detected most frequently and much higher levels of PFBA and PFPeA being found in some samples. The total PFAS concentrations ranged from not detectable to 0.683 μg kg-1. This method could be applied for large scale determination of vegetables to research the migration and accumulation trends of PFASs from the environment to crops in the future.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Identification of a novel advanced glycation end product derived from lactaldehyde

Authors: Fujimoto, S; Murakami, Y; Miyake, H; Hayase, F; Watanabe, H (2019) Bioscience, Biotechnology, and Biochemistry 1-10. HERO ID: 5098204

[Less] Advanced glycation end products (AGEs) are implicated in the development of diabetic complications via . . . [More] Advanced glycation end products (AGEs) are implicated in the development of diabetic complications via the receptor for AGEs (RAGE). We have reported that the 3-hydroxypyridinium (3HP)-containing AGEs derived from α-hydroxyaldehydes physically interact with RAGE and show cytotoxicity. Lactaldehyde (LA) is formed from a reaction between threonine and myeloperoxidase, but no LA-derived AGEs have been characterized. Here, we identify the structure and physiological effects of an AGE derived from LA. We isolated a novel 3HP derivative, 2-acetamido-6-(3-hydroxy-5-methyl-pyridin-1-ium-1-yl)hexanoate, named as N-acetyl-LAPL (lactaldehyde-derived pyridinium-type lysine adduct), from a mixture of LA with Nα-acetyl-L-lysine. LAPL was also detected in the LA-modified protein. LAPL elicited toxicity in PC12 neuronal cells, but the effect was suppressed by the soluble form of RAGE as a decoy receptor. Moreover, surface plasmon resonance-based analysis revealed that LAPL specifically binds to recombinant RAGE. These results indicate that LA generates an AGE containing the 3HP moiety and contributes to RAGE-dependent cytotoxicity. Abbreviations: AGEs: advanced glycation end products; RAGE: receptor for advanced glycation end products; 3HP: 3-hydroxypyridinium; LA: lactaldehyde; LAPL: lactaldehyde-derived pyridinium-type lysine adduct; BSA: bovine serum albumin; GLAP: glyceraldehyde-derived pyridinium; MPO: myeloperoxidase; HFBA: heptafluorobutyric acid; TFA: trifluoroacetic acid; HPLC: high performance liquid chromatography; LC-ESI-QTOF-MS: liquid chromatography-electrospray ionization-quadrupole time-of-flight-mass spectrometry; NMR: nuclear magnetic resonance; LA-BSA: lactaldehyde-modified bovine serum albumin; PBS: phosphate buffered saline, GST, glutathione S-transferase; SPR: surface plasmon resonance; OP-lysine: 2-ammonio-6-(3-oxidopyridinium-1-yl)hexanoate; GLO1: glyoxalase 1; MG, methylglyoxal.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Variation in microbial community structure in surface seawater from Pearl River Delta: Discerning the influencing factors

Authors: Chen, L; Tsui, MMP; Lam, JCW; Hu, C; Wang, Q; Zhou, B; Lam, PKS (2019) Science of the Total Environment 660:136-144. HERO ID: 5024203

[Less] Contamination of perfluoroalkyl acids (PFAAs) is ubiquitously detected in various environments. However, . . . [More] Contamination of perfluoroalkyl acids (PFAAs) is ubiquitously detected in various environments. However, their potential effects on microbial communities remain largely unknown. In this study, surface seawater of the Pearl River Delta (PRD) is sampled to measure PFAA concentrations and profile the structure of free-living microbial community. Total PFAAs concentrations range from 131 to 1563 pg L-1 in surface seawater. PFOS (16-470 pg L-1), PFOA (27-272 pg L-1), PFHpA (18-201 pg L-1) and PFBA (25-152 pg L-1) are the major homologues, indicating continued industrial application or release of PFOS and a gradual shift towards using shorter-chain PFAAs. Concentrations of PFAAs from this recent cruise are much lower than previous reports, which may be due to the effective management of PFAA usage around PRD region. In addition, the microbial community in PRD surface seawater is predominantly colonized by the Proteobacteria phylum (27.2 to 61.5%) and the Synechococcus genus (5.6 to 38.6%). The structure of the microbial communities varies among stations, mainly resulting from different abundances of Synechococcus, Prochlorococcus and Nitrosopumilus. Geochemical parameters (e.g., nutrients and salinity) and phytoplankton are significantly associated with the microbial community dynamics in surface seawater. In the interactive network of microbiota, a subset of bacteria (i.e., Fluviicola, Nitrosopumilus, Limnohabitans, Sediminibacterium, C39 and Polynucleobacter) shows significantly positive correlations with PFAAs (R > 0.6; P < 0.001). Overall, this study gives a timely monitoring of PFAA pollution around PRD area. Shift in environmental microbiota by geochemical factors and phytoplankton is also observed, which may affect biogeochemical cycling.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Perfluoroalkyl substances in groundwater and home-produced vegetables and eggs around a fluorochemical industrial park in China

Authors: Bao, J; Yu, WJ; Liu, Y; Wang, X; Jin, YH; Dong, GH (2019) Ecotoxicology and Environmental Safety 171:199-205. HERO ID: 5080600

[Less] High-level contaminations of perfluoroalkyl substances (PFASs) were determined in both surface water . . . [More] High-level contaminations of perfluoroalkyl substances (PFASs) were determined in both surface water and groundwater around a fluorochemical industrial park (FIP) in Fuxin, China, over the past few years. Yet little is known about whether groundwater PFAS contaminations in Fuxin could be introduced into home-produced vegetables and eggs in local residences via the application of groundwater for the irrigation or feeding purposes. In the present study, ten PFAS analytes were analyzed via high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) to investigate the extent of PFAS contaminations in the groundwater, soil, and home-produced vegetable and egg samples derived from Fuxin. As the predominant PFAS contaminants, perfluorobutane sulfonate (PFBS) and perfluorooctanoic acid (PFOA) were observed in groundwater beneath the Fuxin FIP with the maximum concentrations of 21.2 and 2.51 µg/L, respectively, which were 24-fold and 5-fold higher individually compared to those reported previously. Both of them were also higher than the updated health advisories for PFBS and PFOA in drinking water issued by the Minnesota Department of Health and the US Environmental Protection Agency. In addition, short-chain PFASs involving perfluorobutanoic acid (PFBA) and PFBS were found to be the major contaminants in both home-produced vegetables and eggs from the residential gardens around the FIP. Statistically significant relationships were determined between the levels of PFBA, PFOA, and PFBS in local groundwater and those observed in home-produced vegetables (p = 0.003, p = 0.025, and p < 0.001), suggesting potential entry of those PFAS contaminants into home-produced vegetables via irrigation with groundwater beneath the FIP.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Occurrence of perfluorinated compounds in agricultural environment, vegetables, and fruits in regions influenced by a fluorine-chemical industrial park in China

Authors: Li, P; Oyang, X; Zhao, Y; Tu, T; Tian, X; Li, L; Zhao, Y; Li, J; Xiao, Z (2019) Chemosphere 225:659-667. HERO ID: 5079816

[Less] The occurrence of perfluorinated compounds (PFCs) in vegetables and fruits, as well as agricultural . . . [More] The occurrence of perfluorinated compounds (PFCs) in vegetables and fruits, as well as agricultural environment, was investigated in the downstream regions of Changshu fluorine-chemical industrial park (CFCIP) in China. Twenty-one PFCs were analyzed in irrigation water, agricultural soil, typical vegetables, and fruits, with the maximum total PFC concentrations of 369.9 ng/L, 64.7 ng/g dw, 11.5 ng/g ww, and 10.5 ng/g ww, respectively. Short-chained perfluoroalkyl carboxylic acids (PFCAs) such as perfluorooctanoic acid (PFOA), perfluorobutanoic acid (PFBA), and perfluorohexanoic acid were the dominant PFCs in terms of their concentrations and detection frequency. PFCs in irrigation water and agricultural soils showed a decreasing trend with increasing distance from CFCIP, while this pattern was not observed in agricultural products. The predominant compounds varied in different vegetables and fruits. Simultaneous bioaccumulation of PFBA and PFOA was found in melons and solanaceous species and pears. Leafy vegetables and grapes exhibited high bioaccumulation of PFOA and PFBA, respectively. Health risk assessment by calculating estimated daily intake showed that no direct risk was caused by the consumption of vegetables and fruits for the residents in the investigated regions. However, the tolerable weekly intake of PFOA exceeded the established thresholds for the adult residents. A comprehensive health assessment of the dietary exposure of PFCs, including all exposure pathways, in fluorine-chemical industrial park-impacted regions is needed.