Health & Environmental Research Online (HERO)


PFPeA (2706-90-3)


192 References Were Found:

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Deriving environmental quality standards for perfluorooctanoic acid (PFOA) and related short chain perfluorinated alkyl acids

Authors: Valsecchi, S; Conti, D; Crebelli, R; Polesello, S; Rusconi, M; Mazzoni, M; Preziosi, E; Carere, M; Lucentini, L; Ferretti, E; Balzamo, S; Simeone, MG; Aste, F (2017) Journal of Hazardous Materials 323:84-98. HERO ID: 3748953

[Less] The evidence that in Northern Italy significant sources of perfluoroalkylacids (PFAA) are present induced . . . [More] The evidence that in Northern Italy significant sources of perfluoroalkylacids (PFAA) are present induced the Italian government to establish a Working Group on Environmental Quality Standard (EQS) for PFAA in order to include some of them in the list of national specific pollutants for surface water monitoring according to the Water Framework Directive (2000/60/EC). The list of substances included perfluorooctanoate (PFOA) and related short chain PFAA such as perfluorobutanoate (PFBA), perfluoropentanoate (PFPeA), perfluorohexanoate (PFHxA) and perfluorobutanesulfonate (PFBS), which is a substitute of perfluorooctanesulfonate. For each of them a dossier collects available data on regulation, physico-chemical properties, emission and sources, occurrence, acute and chronic toxicity on aquatic species and mammals, including humans. Quality standards (QS) were derived for the different protection objectives (pelagic and benthic communities, predators by secondary poisoning, human health via consumption of fishery products and water) according to the European guideline. The lowest QS is finally chosen as the relevant EQS. For PFOA a QS for biota was derived for protection from secondary poisoning and the corresponding QS for water was back-calculated, obtaining a freshwater EQS of 0.1μgL(-1). For PFBA, PFPeA, PFHxA and PFBS threshold limits proposed for drinking waters were adopted as EQS.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Perfluoroalkyl acids (PFAAs) in sediments from rivers of the Pearl River Delta, southern China

Authors: Liu, B; Zhang, H; Li, J; Dong, W; Xie, L (2017) Environmental Monitoring and Assessment 189:213. HERO ID: 3859703

[Less] Having been largely used in industrial and household products, perfluoroalkyl acids (PFAAs) appear in . . . [More] Having been largely used in industrial and household products, perfluoroalkyl acids (PFAAs) appear in environmental and biological systems with prevalence and persistence and have raised great concern in recent years. The present study is aimed at studying concentrations and composition profiles of 16 PFAAs in surface sediments collected from 51 sampling locations in 4 main rivers of the Pearl River Delta, one of the economy-developed areas in China. The total PFAA concentrations (∑ PFAAs) were determined in a wide range of 1.89-15.1 ng g(-1) dw (dry weight) with an average concentration to be 3.54 ng g(-1) dw. Higher ∑ PFAAs were observed in the downstream of Dongjiang River and the Pearl River, possibly due to the discharge of industrial wastewater. Perfluoropentanoic acid (PFPeA) and perfluorooctane sulfonate (PFOS) were the dominant PFAAs, accounting for 51 to 85% of ∑ PFAAs in 27% of the samples. High PFPeA concentrations in sediments of urban river were scarcely observed in previous studies worldwide. The sources of short-chain perfluoroalkyl carboxylic acids (PFCAs) were significantly different from those of other PFAAs. Preliminary hazard assessment proved negligible for PFOS, perfluorooctanoic acid (PFOA), PFPeA, and perfluorohexanoic acid (PFHxA) concentrations in sediments from rivers of the Pearl River Delta.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Highly efficient and stable Zr-doped nanocrystalline PbO2 electrode for mineralization of perfluorooctanoic acid in a sequential treatment system

Authors: Xu, Z; Yu, Y; Liu, H; Niu, J (2017) Science of the Total Environment 579:1600-1607. HERO ID: 3858263

[Less] Zr-doped nanocrystalline PbO2 (Zr-PbO2) film electrodes were prepared at different bath temperatures. . . . [More] Zr-doped nanocrystalline PbO2 (Zr-PbO2) film electrodes were prepared at different bath temperatures. The Zr-PbO2 electrode doped at 75°C (75-Zr-PbO2) featured high oxygen evolution overpotential, large effective area and good electrocatalytic performance. The oxygen evolution potential and the effective area of 75-Zr-PbO2 achieved 1.91V (vs. SCE) and 9.1cm(2), respectively. The removal efficiency and the defluorination ratio of PFOA reached 97.0% and 88.1% after 90min electrolysis. The primary mineralization products (i.e., F(-) and intermediates) and their change trends were determined. The 75-Zr-PbO2 electrode was introduced to sequentially treat the PFOA wastewater. In an 116h of 75-Zr-PbO2 electrocatalysis sequential process, the PFOA, PFHpA, PFHxA, PFPeA, PFBA, PFPrA, TFA, and TOC concentrations were reduced to below 30, 2.5, 1.3, 1.0, 0.5, 0.2, 0.1, and 9mgL(-1), respectively, demonstrating the promising application of the sequential treatment system for the treatment of PFOA wastewater.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Quantitation of levodopa and carbidopa in rat plasma by LC-MS/MS: The key role of ion-pairing reversed-phase chromatography

Authors: Chi, J; Ling, Y; Jenkins, R; Li, F (2017) Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences 1054:1-9. HERO ID: 3860312

[Less] A simple and selective bioanalytical method was developed for simultaneous determination of levodopa . . . [More] A simple and selective bioanalytical method was developed for simultaneous determination of levodopa and carbidopa in rat plasma by LC-MS/MS. Levodopa and carbidopa are small polar molecules, posing challenges in the development of selective and efficient chromatography conditions. Perfluoropentanoic acid (PFPA), a volatile ion-pairing agent, was utilized to enhance chromatographic characteristics of both compounds in the reversed-phase mechanism. The ion-pairing chromatography played an essential role in mitigating matrix effects and achieving adequate separation between interfering background peaks and those of the analytes of interest, especially for levodopa. A 96-well based, automated liquid-liquid extraction, via the use Hamilton NIMBUS liquid handlers, was developed. Butyl alcohol, when mixed with ethyl acetate, greatly increased the recovery of both levodopa and carbidopa. The addition of PFPA further enhanced recovery for both analytes. Sodium metabisulfite, an antioxidant, was used to stabilize levodopa and carbidopa in rat plasma. The method was validated in the ranges of 50-10,000ng/mL and 25-5000ng/mL for levodopa and carbidopa, respectively, using levodopa-d3 and carbidopa-d3 as internal standards. The validated method was successfully applied to analyze rat plasma samples from in-life studies.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Perfluoroalkyl acids in the water cycle from a freshwater river basin to coastal waters in eastern China

Authors: Zhu, X; Jin, L; Yang, J; Wu, J; Zhang, B; Zhang, X; Yu, N; Wei, S; Wu, J; Yu, H (2017) Chemosphere 168:390-398. HERO ID: 3860313

[Less] The distribution of perfluoroalkyl acids (PFAAs), one class of persistent organic pollutants, in groundwater, . . . [More] The distribution of perfluoroalkyl acids (PFAAs), one class of persistent organic pollutants, in groundwater, especially in confined aquifers remains poorly understood. In this study, we investigated the occurrence of 12 PFAAs through a water cycle from the Huai River Basin to the Yellow Sea, including confined aquifers, unconfined aquifers, rivers, and coastal waters. We found the ubiquity of PFAAs in all types of samples, including those from confined aquifers (2.7-6.8 ng/L). Perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) were the major PFAAs in all samples, accounting for an average of 49.1% (0.8-84.8%) and 33.3% (6.3-92.2%) of total PFAAs, respectively. Comparing the concentration of PFOA with that of PFOS, we found a higher concentration of PFOA in rivers and a higher concentration of PFOS in confined aquifers. Short-chain perfluoropentanoic acid accounted for an average of 10.3% (1.9-24.6%) of total PFAAs in rivers and coastal waters. Branched isomers of both PFOA and PFOS were detected in most samples (36/42 and 39/42, respectively). One-way analysis of variance indicated a significant difference in the profiles of PFAAs among the different types of water samples. Principal component analysis suggested that rainwater and recent uses of PFAAs could be the major sources of PFAAs in confined aquifers, while recent and current uses of PFAAs could be the major source of PFAAs in unconfined aquifers, rivers and coastal waters. The risk quotients of PFOA and PFOS in groundwater and rivers were 2-3 orders of magnitude lower than unity, indicating no immediate risks via drinking water consumption.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Poly(HEMA-co-HEMA-PFPA): Synthesis and preparation of stable micelles encapsulating imaging nanoparticles

Authors: Sundhoro, M; Park, J; Jayawardana, KW; Chen, X; Jayawardena, HSN; Yan, M (2017) Journal of Colloid and Interface Science 500:1-8. HERO ID: 3860379

[Less] We report the preparation of stable micelles from random copolymers of 2-hydroxyethyl methacrylate (HEMA) . . . [More] We report the preparation of stable micelles from random copolymers of 2-hydroxyethyl methacrylate (HEMA) and perfluorophenyl azide (PFPA)-derivatized HEMA (HEMA-PFPA). The copolymers were synthesized by RAFT polymerization at room temperature under mild conditions without affecting the azide functionality. Upon addition of water to the copolymer solution in DMSO, the random copolymers self-assembled into micelles even at the percentage of HEMA-PFPA as low as 4.5%. The size of the micelles can be controlled by the molecular weight and the concentration of the copolymer, and the percentage of HEMA-PFPA in the copolymer. In addition, iron oxide nanoparticles and quantum dots were successfully encapsulated into the micelles with high encapsulation efficiency (∼80%). These nanoparticles, which were hydrophobic and formed agglomerates in water, became fully dispersed after encapsulating into the micelles. The micelles were stable and the size remained unchanged for at least 6months.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

The use of carbon adsorbents for the removal of perfluoroalkyl acids from potable reuse systems

Authors: Inyang, M; Dickenson, ERV (2017) Chemosphere 184:168-175. HERO ID: 3858250

[Less] Bench- and pilot-scale sorption tests were used to probe the performance of several biochars at removing . . . [More] Bench- and pilot-scale sorption tests were used to probe the performance of several biochars at removing perfluoroalkyl acids (PFAA) from field waters, compared to granular activated carbon (GAC). Screening tests using organic matter-free water resulted in hardwood (HWC) (Kd = 41 L g(-1)) and pinewood (PWC) (Kd = 49 L g(-1)) biochars having the highest perfluorooctanoic acid (PFOA) removal performance that was comparable to bituminous coal GAC (Kd = 41 L g(-1)). PWC and HWC had a stronger affinity for PFOA sorbed in Lake Mead surface water (KF = 11 mg((1-n)) L(n) g(-1)) containing a lower (2 mg L(-1)) dissolved organic carbon (DOC) concentration than in a tertiary-filtered wastewater (KF = 8 mg((1-n)) L(n) g(-1)) with DOC of 4.9 mg L(-1). A pilot-scale study was performed using three parallel adsorbers (GAC, anthracite, and HWC biochar) treating the same tertiary-filtered wastewater. Compared to HWC, and anthracite, GAC was the most effective in mitigating perfluoropentanoic acid (PFPnA), perfluorohexanoic acid (PHxA), PFOA, perfluorooctane sulfonic acid (PFOS), and DOC (45-67% removed at 4354 bed volumes) followed by HWC, and then anthracite. Based on bench- and pilot-scale results, shorter-chain PFAA [perfluorobutanoic acid (PFBA), PFPnA, or PFHxA] were more difficult to remove with both biochar and GAC than the longer-chain, PFOS and PFOA.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Uptake and elimination kinetics of perfluoroalkyl substances in submerged and free-floating aquatic macrophytes: Results of mesocosm experiments with Echinodorus horemanii and Eichhornia crassipes

Authors: Pi, N; Ng, JZ; Kelly, BC (2017) Water Research 117:167-174. HERO ID: 3856456

[Less] Studies investigating the bioaccumulation behavior of perfluoroalkyl substances (PFASs) in aquatic macrophytes . . . [More] Studies investigating the bioaccumulation behavior of perfluoroalkyl substances (PFASs) in aquatic macrophytes are limited. The present study involved controlled mesocosm experiments to assess uptake and elimination rate constants (ku,ke), bioconcentration factors (BCFs) and translocation factors (TFs) of several perfluoroalkyl carboxylic acids (PFCAs) and perfluoroalkane sulfonic acids (PFSAs) in two aquatic plant species, including one submerged species (Echinodorus horemanii) and one free-floating species (Eichhornia crassipes). The results indicated all PFASs were readily accumulated in these aquatic macrophytes. ku and BCFs increased with increasing perfluoroalkyl chain length. For PFCAs and PFSAs with identical perfluoroalkyl chain length, the corresponding PFSA exhibited higher bioaccumulation potential. On a whole-plant basis, the bioaccumulation potential of PFASs in submerged and free-floating macrophytes were comparable, indicating sorption to plant biomass is similar in the different species. Conversely, when considering accumulation in foliage, BCFs in the free-floating macrophyte were substantially lower compared to submerged species, especially for longer-chain PFASs. Compounds with shorter perfluoroalkyl chain length (PFBS, PFPeA and PFHxA) exhibited preferential translocation to leaf tissue (TFs >1). BCFs exhibited a sigmoidal relationship with pefluoroalkyl chain length, membrane-water distribution coefficients (Dmw), protein-water distribution coefficients (Dpw) and organic-water partition coefficients (Koc). For these trends, maximum BCF values were exhibited by long-chain PFCAs, with a log Dmw, log Dpw and log Koc of 6.47, 5.72 and 5.04, respectively. These findings are useful for future design and implementation of phytoremediation systems, as well for future develop of mechanistic models for predicting the environmental fate and distribution of these contaminants of concern.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Perfluorinated alkyl substances in serum of the southern Chinese general population and potential impact on thyroid hormones

Authors: Li, Y; Cheng, Y; Xie, Z; Zeng, F (2017) Scientific Reports 7:43380. HERO ID: 3856460

[Less] In this study, eight perfluorinated alkyl substances (PFASs) and five thyroid hormones (TSH, FT4, FT3, . . . [More] In this study, eight perfluorinated alkyl substances (PFASs) and five thyroid hormones (TSH, FT4, FT3, TGAb, and TMAb) were determined in 202 human serum samples of the general population of Guangdong, Guangxi and Hainan provinces in southern China. Σ8PFASs concentrations ranged from 0.85 to 24.3 ng/mL with a mean value of 4.66 ng/mL. The PFASs composition profiles of human serum samples nearly make no difference at different locations. A significant increase was observed for ∑8PFASs, PFOS, and PFHxS concentrations with age (p < 0.01). Gender-related differences were found; PFOS, PFHxS, PFBS, and PFOA levels were higher in males (p < 0.05), and the mean concentration of ∑8PFASs was 1.5 times greater in males (6.02 ng/mL) than in females (4.15 ng/mL). PFOS and ∑8PFASs were significantly negatively correlated with FT3 and FT4 and positively correlated with TSH while PFPeA and PFHxA were significantly positively correlated with TGAb and TMAb in all the samples. The opposite associations between FT3, TSH and PFOS, PFOA and PFHxS levels in hypothyroidism and hyperthyroidism group indicate that the PFOS, PFOA and PFHxS enhance the negative feedback mechanisms of the thyroid gland.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Perfluorinated alkyl substances (PFASs) in northern Spain municipal solid waste landfill leachates

Authors: Fuertes, I; Gómez-Lavín, S; Elizalde, MP; Urtiaga, A (2017) Chemosphere 168:399-407. HERO ID: 3856464

[Less] Landfill leachates have been recognized as significant secondary sources of poly- and perfluoroalkyl . . . [More] Landfill leachates have been recognized as significant secondary sources of poly- and perfluoroalkyl substances (PFASs). This study presents data on the occurrence and concentration of 11 perfluoroalkyl carboxylates (PFCAs) and 5 perfluoroalkyl sulfonates (PFSAs) in leachates from 4 municipal solid waste landfill sites located across northern Spain. To the best of our knowledge, this is the first report of the presence of PFASs in Spanish landfill leachates. Two of the landfill sites applied on-site treatment using membrane bioreactors (MBR), and its effect on PFASs occurrence is also reported. Total PFASs (∑PFASs) in raw leachates reached 1378.9 ng/L, while in treated samples ∑PFASs was approximately two-fold (3162.3 ng/L). PFCAs accounted for the majority of the detected PFASs and perfluorooctanoic acid (PFOA) was the dominant compound in raw leachates (42.6%), followed by shorter chain PFHxA (30.1%), PFPeA and PFBA. The age of the sites might explain the PFASs pattern found in raw leachates as all of them were stabilized leachates. However, PFASs profile was different in treated samples where the most abundant compound was PFHxA (26.5%), followed by linear perfluorobutane sulfonate (L-PFBS) (18.7%) and PFOA (17.7%). The overall increase of the PFASs content as well as the change in the PFASs profile after the MBR treatment, could be explained by the possible degradation of PFASs precursors such as fluorotelomer alcohols or fluorotelomer sulfonates. Using the volume of leachates generated in the landfill sites, that served 1.8 million people, the discharge of 16 ∑PFASs contained in the landfill leachates was estimated as 1209 g/year.