Health & Environmental Research Online (HERO)


Dibutyl sebacate (109-43-3)


130 References Were Found:

Archival Material
Archival Material

ChemID plus advanced. Dibutyl adipate, RN: 105-99-7

Author: NLM (2019) HERO ID: 5077978


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

An aliphatic ester diisopropyl sebacate exhibited an adjuvant effect on fluorescein isothiocyanate-induced contact hypersensitivity mouse models

Authors: Kurohane, K; Kimura, A; Terasawa, R; Kobayashi, K; Suzuki, W; Matsuoka, T; Imai, Y (2018) Biological and Pharmaceutical Bulletin 41:147-150. HERO ID: 5043597

[Less] Alternative plasticizers have become more popular due to health concerns about phthalate esters. We . . . [More] Alternative plasticizers have become more popular due to health concerns about phthalate esters. We demonstrated that phthalate esters enhanced skin sensitization to fluorescein isothiocyanate (FITC) in mouse contact hypersensitivity models. Alternative plasticizers have not been well studied as to their effect on the immune system. We previously found that diisopropyl adipate (DIPA), an aliphatic dicarboxylic acid ester, enhanced skin sensitization to FITC. Sebacate esters are also widely used as alternative plasticizers. Here we tested diisopropyl sebacate (DIPS), which has the same alcohol with an aliphatic dicarboxylic acid of longer chain, using BALB/c mice. The results showed that DIPS facilitated skin sensitization to FITC and increased FITC-presenting dendritic cell trafficking from the skin to draining lymph nodes. Furthermore, DIPS activated transient receptor potential ankyrin 1 (TRPA1). The latter feature has been commonly observed for phthalate esters and DIPA, which have adjuvant effects. In summary, the adjuvant effect of a sebacate ester was demonstrated in a mouse model.

Data/Software
Data/ Software

OncoLogic - A computer system to evaluate the carcinogenic potential of chemicals. Version 8.0

Author: U.S. EPA (2018) U.S. Environmental Protection Agency. [Computer Program] HERO ID: 4825458


Journal Article
Journal Article

Effect of substitution of plasticizer dibutyl phthalate with dibutyl sebacate on Eudragit® RS30D drug release rate control

Authors: Chaudhary, RS; Patel, T; Kumar, JR; Chan, M (2018) Pharmaceutical Development and Technology 1-7. HERO ID: 4828873

[Less] In the current study, the influence of type of plasticizer used with Eudragit® RS 30D on the drug release . . . [More] In the current study, the influence of type of plasticizer used with Eudragit® RS 30D on the drug release was investigated in solid dosage form extrusion/spheronization, and film coating. The drug pellets were coated for controlling drug release with Eudragit® RS 30D containing dibutyl phthalate and compared with dibutyl sebacate as an alternative plasticizer. To study the influence of pH of the dissolution medium on the drug release profile, capsules are tested for drug release profile at pH 1.2, 4.4, and 6.3. Additionally, the aging effect on the curing of Eudragit® RS 30D is evaluated by exposing the capsules dosage form to room temperature (25 °C ± 2 °C/60% ± 5% RH) for time 0, 3, 6, and 9 months, accelerated temperature (40 °C ± 2 °C/75% ± 5% RH) for time 0, 3, and 6 months, and intermediate temperature (30 °C ± 2 °C/65% ± 5% RH) for time 0, 6, and 9 months. The replacement of dibutyl phthalate, with dibutyl sebacate for polymer coating system in similar concentration is comparable with respect to plasticization effect. The coalescence of the polymer particles is not changed and requires no additional processing parameter control or additional curing time.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

The Influence of Plasticisers on Response Characteristics of Anionic Surfactant Potentiometric Sensor

Authors: Karnas, M; Sakac, N; Jozanovic, M; Tsakiri, M; Kopriva, M; Andric, EK; Sak-Bosnar, M (2017) HERO ID: 4829015

[Less] Six different plasticisers, 2-nitrophenyl octyl ether (P1), bis(2-ethylhexyl) phthalate (P2), bis (2-ethylhexyl) . . . [More] Six different plasticisers, 2-nitrophenyl octyl ether (P1), bis(2-ethylhexyl) phthalate (P2), bis (2-ethylhexyl) sebacate (P3), 2-nitrophenyl phenyl ether (P4), dibutyl phthalate (P5) and dibutyl sebacate (P6), were incorporated into PVC-based surfactant sensors, and their influence on the determination of anionic surfactants (sodium laurylsulfate (SDS) and sodium dodecylbenzenesulfonate (DBS)) was investigated. Dimethyldioctadecylammonium-tetraphenylborate (DDA-TPB) was used as an ion-pair in the membrane. The sensors containing plasticisers P1-P5 exhibited a sub-Nernstian slope value ranging from -46.4 to -54.8 (mV/decade of activity), while P6 exhibited a super-Nernstian slope value of -66.3 (mV/decade of activity). All the obtained titration curves displayed well defined and sharp inflexion points. Due to the best analytical performance and its low price, the sensor containing dibutyl phthalate (P5) was selected for further investigation. It also provides fast dynamic response and the highest value of potential change at the end-point, allowing reliable end-point location even at low concentration levels of analyte. The linear response renge of the sensor was 6.1 x 10(-3) to 7.2 x 10(-7) M with the sub-Nernstian slope value of -53.1 +/- 0.6 (mV/decade of activity) and the lower detection limit of 3.9 x 10(-7) M. The commonly used compounds in product formulations did not interfere with the measurements. Anionic surfactant content was successfully determined in commercial dishwashing detergents.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Optical measurements from single levitated particles using a linear electrodynamic quadrupole trap

Authors: Hart, MB; Sivaprakasam, V; Eversole, JD; Johnson, LJ; Czege, J (2015) Applied Optics 54:F174-F181. HERO ID: 3363559

[Less] We have recently made advancements in a linear electrodynamic quadrupole (LEQ) device for capturing . . . [More] We have recently made advancements in a linear electrodynamic quadrupole (LEQ) device for capturing and levitating either single or multiple micro-particles that provides significant improvements in capture efficiency, reliability, and optical measurement access. We have used our LEQ to trap particles ranging from 30 to less than 0.5 μm in size and provide a controlled environment to study particle physical/chemical dependencies on temperature, relative humidity, and gas constituents. To demonstrate this approach, we present data and analysis of liquid-droplet evaporation rates for two materials: glycerol and dibutyl sebacate. Droplet size was monitored as a function of time by two independent optical methods: direct imaging and fixed-angle light scattering. This new approach provides a means to rapidly characterize a wide range of aerosol particle properties and a platform for development of new aerosol optical-diagnostic measurements.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Fabrication of hollow fiber microfiltration membrane from PVDF/DBP/DBS system via thermally induced phase separation process

Authors: Song, Z; Yang, Wei; Zhang, J; Li, Ye; Yuan, S (2015) HERO ID: 4829004

[Less] Polyvinylidene fluoride (PVDF) membranes were prepared via a thermally induced phase separation (TIPS) . . . [More] Polyvinylidene fluoride (PVDF) membranes were prepared via a thermally induced phase separation (TIPS) process using mixed diluent consisting of dibutyl phthalate (DBP) and dibutyl sebacate (DBS). The compatibility between PVDF and mixed diluent was predicted via the solubility parameter theory and verified by experimental results. The effects of mixed diluent composition on cloud point temperature, crystallization temperature, crystallinity, crystal phase and morphology of the membrane were investigated. As a result, as DBS mass fraction in mixed diluent increased, the cloud point temperature and the crystallinity increased, the crystal phase transformed from beta phase to alpha phase and the morphology of the membrane cross-section changed from spherulitic structures to a bicontinuous structure. PVDF hollow fiber membranes were prepared successfully with the PVDF/DBP/DBS system via the TIPS method. The coagulant composition had a significant influence on the water permeability. When the dimethylacetamide (DMAc) content in the coagulant was 60%, the water permeability reached 877 l/m(2).h,while the rejection rate to the particles with a size of 200-500 nm was above 95%.

Technical Report
Technical Report

Dibutyl adipate: short-term toxicity to aquatic invertebrates: 001 weight of evidence | experimental result

Author: ECHA (2014) HERO ID: 5077961


Technical Report
Technical Report

Dibutyl adipate: long-term toxicity to aquatic invertebrates: 001 key | experimental result

Author: ECHA (2014) HERO ID: 5077962


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

In vitro and in vivo evaluation of gliclazide push-pull osmotic pump coated with aqueous colloidal polymer dispersions

Authors: Tang, X; Tai, LY; Yang, XG; Chen, F; Xu, HM; Pan, WS (2013) Drug Development and Industrial Pharmacy. HERO ID: 1249977

[Less] The objective of present work was to design and evaluate gliclazide push-pull osmotic pump (PPOP) coated . . . [More] The objective of present work was to design and evaluate gliclazide push-pull osmotic pump (PPOP) coated with aqueous colloidal polymer dispersions-Eudragit(®) RL 30D and Eudragit(®) RS 30D. The influence of diacetin, diethyl phthalate (DEP), dibutyl sebacate (DBS) and triethyl citrate (TEC) on the free Eudragit(®) RL 30D and Eudragit(®) RS 30D films as plasticizers on drug release were studied. Among these four plasticizers, diacetin offered the smoothest surface of the cast films, and it displayed greatest water vapor transmission coefficient. Free RL and RS films with diacetin also exhibited greatest erosion compared with the other three plasticizers. On the other hand, TEC, DEP and DBS showed greater water absorption. When compared with CA-coated gliclazide PPOP, Eudragit-coated ones showed a f(2) factor of 71.7, indicating the similarity between the release profile of the two formulations. The prepared Eudragit-coated gliclazide PPOP showed typical Zero-order release characteristics, with R being 0.9953. In the in vivo evaluation, the mean relative oral bioavailability of Eudragit-coated PPOP compared to CA-coated ones was 106.9%, demonstrating good bioequivalence. Both of their in vitro-in vivo correlation (IVIVC) showed linear relationship, with R(2) being 0.9955 (Eudragit-coated PPOP) and 0.9987 (CA-coated PPOP), respectively. These results suggested that PPOP coated with Eudragit(®) RL 30D and RS 30D could overcome drawbacks of organic solution coating and promote the development of PPOP.