Health & Environmental Research Online (HERO)


Gluconates (527-07-1, 299-27-4, 526-95-4, 90-80-2, & 299-28-5)


574 References Were Found:

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Metabolomics analysis reveals potential mechanisms of tolerance to excess molybdenum in soybean seedlings

Authors: Xu, S; Hu, C; Hussain, S; Tan, Q; Wu, S; Sun, X (2018) Ecotoxicology and Environmental Safety 164:589-596. HERO ID: 4830850

[Less] Most plants exhibit strong tolerance to excess molybdenum (Mo). However, the metabolic profile and tolerance . . . [More] Most plants exhibit strong tolerance to excess molybdenum (Mo). However, the metabolic profile and tolerance mechanisms of plants in response to excess Mo remain unknown. We comprehensively analyzed changes in the metabolic profiles of leaves and roots in soybean (Glycine max L.) seedlings cultured under normal-Mo and excess-Mo conditions by using ultra performance liquid chromatography (UPLC) combined with MS/MS (mass spectrometry). There were 42 differential metabolites in the roots and 19 differential metabolites in the leaves in response to excess Mo stress. In roots, the organic acids, levels of gluconic acid, D-glucarate and citric acid increased by 107.63-, 4.42- and 2.87-folds after excess Mo exposure. Several hormones (salicylic acid, jasmonic acid) and lipids (PG, MG, DG etc) also increased significantly under excess Mo condition. Metabolites related to ascorbate-glutathione metabolism and flavonoid and isoflavone biosynthesis notably accumulated in roots. Only lipid metabolism and salicylic acid accumulation were induced in leaves under excess Mo stress. It is speculated that organic compounds such as 2-oxoarginine, L-nicotine, gluconic acid, D-glucurate, and citric acid played important roles to chelate Mo and reduce its toxicity. Signaling molecules (JA, SA, and some lipids) and non-enzyme antioxidants such as flavonoids/isoflavones act synergistically to detoxify ROS and contribute to Mo tolerance in soybean seedlings. More metabolic pathways were induced by Mo excess in roots than in leaves, suggesting that roots play more implant role in Mo tolerance.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Development of an HPLC/UV method for the evaluation of extractables and leachables in plastic: Application to a plastic-packaged calcium gluconate glucoheptonate solution

Authors: Legrand, P; Desdion, A; Boccadifuoco, G; Dufaÿ Wojcicki, A; Worsley, A; Boudy, V; Dufay, SG (2018) Journal of Pharmaceutical and Biomedical Analysis 155:298-305. HERO ID: 4837204

[Less] Calcium gluconate glucoheptonate (GGCa) is known to interact with glass containers, leading to the leaching . . . [More] Calcium gluconate glucoheptonate (GGCa) is known to interact with glass containers, leading to the leaching of aluminum from the glass into the solution at toxic level. Therefore, plastic containers seem to be a preferable packaging alternative. Nevertheless, plastics contain potentially toxic additives which could be released into the solution. In order to study content container interaction between GGCa and two plastic containers (polypropylene PP and polyethylene PE containers), an HPLC-PDA method was developed to separate, detect and quantify eleven additives commonly found in plastic materials, with good limit of detection and quantification. This method was then applied to evaluate the compatibility between GGCa and the two plastic containers. After 3 months of storage at 25 °C, none of the eleven additives were detected in GGCa solutions. The safety concern threshold (SCT) and of the analytical evaluation threshold (AET) were evaluated to discriminate the need to identify and qualify unknown peaks.

Technical Report
Technical Report

G06 - Ames summary data: gluono delta lactone

Author: NTP (2018) HERO ID: 4940109


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Nonenzymatic determination of glucose at near neutral pH values based on the use of nafion and platinum black coated microneedle electrode array

Authors: Chinnadayyala, SR; Park, I; Cho, S (2018) Microchimica Acta 185:250. HERO ID: 4946816

[Less] The authors report on a microneedle-based amperometric nonenzymatic glucose sensor for painless and . . . [More] The authors report on a microneedle-based amperometric nonenzymatic glucose sensor for painless and continuous monitoring of glucose. It consists of 3 × 5 sharp stainless steel microneedles micromachined from a stainless steel substrate. The microneedles are 600 and 100 μm in height and width, respectively. Nafion and platinum black were sequentially coated onto the tip of gold-coated microneedles and used for nonenzymatic (direct) sensing of glucose. Attractive features of the modified microneedle electrode include (a) a low working potential (+0.12 V vs. Ag/AgCl), (b) a linear response in the physiologically relevant range (1-40 mM), (c) a sensitivity as high as 175 μA mM-1 cm-2, (d) a 23 μM detection limit, and (e) a response time of 2 s. The sensor also exhibits good reproducibility and stability. The sensor is selective for glucose even in the presence of 10-fold higher concentrations of ascorbic acid, lactic acid, dopamine, uric acid, and acetaminophen. Graphical abstract Schematic representation of the fabrication sequence for a nonenzymatic electrochemical glucose sensor using Nafion and platinum black coated microneedle electrode array. The sensor is based on measuring the faradaic current at +0.12 V vs. Ag/AgCl by the direct electrochemical oxidation of glucose to gluconic acid on the surface of a Pt black sensing layer.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Dynamic corrosion behavior of superhydrophobic surfaces

Authors: Li, CQ; Zhu, MY; Ou, JF; Lu, YL; Wang, FJ; Li, W (2018) HERO ID: 4946804

[Less] For superhydrophobic surfaces immersed in water, a thin layer of air could be entrapped in the solid/liquid . . . [More] For superhydrophobic surfaces immersed in water, a thin layer of air could be entrapped in the solid/liquid interface. This air may hinder the diffusion of dissolved corrosive species (such as Cl- ions in water) to the metallic substrate and, consequently, protect the metal from corrosion. However, in the dynamic water, the relative motion between the solid and the liquid would labilize the entrapped air and, consequently, decrease the corrosion resistance. In this work, to clarify the role of water flow velocity in such corrosion behavior, a superhydrophobic surface on aluminum substrates coded as Al-HCl-H2O-BT-SA was prepared by sequential treatment with HCl, boiling water, bis-(-triethoxysilylpropyl)-tetrasulfide (KH-Si69, BT) and stearic acid (SA). The contrast samples coded as Al-HCl-BT-SA, Al-HCl-H2O-SA, and Al-HCl-SA were also prepared similarly by omitting the treatment in boiling-water, the BT passivation, and the treatment in boiling-water/passivation by BT, respectively. These samples were then immersed into an aqueous solution of NaCl with different flow velocity (0, 0.5, 1.0, 1.5, and 2.0 m s(-1)), and its dynamic corrosion behavior was investigated. The results showed that, as the flow velocity increased, the corrosion resistance of the Al-HCl-H2O-BT-SA sample indeed deteriorated. However, compared with the contrast samples of Al-HCl-BT-SA, Al-HCl-H2O-SA, and Al-HCl-SA, the deterioration in corrosion resistance for the Al-HCl-H2O-BT-SA sample was much lower, implying that the dynamic corrosion resistance of the superhydrophobic surfaces was closely related with the micro-structures and the organic passivated layers. The present study therefore provided a fundamental understanding for the applications of superhydrophobic samples to prevent the corrosion, especially, for various vessels in dynamic water.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

The effect of carrageenan on the acid-induced aggregation and gelation conditions of quinoa proteins

Authors: Montellano Duran, N; Galante, M; Spelzini, D; Boeris, V (2018) Food Research International 107:683-690. HERO ID: 4948549


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Metabolic Footprinting of Fermented Milk Consumption in Serum of Healthy Men

Authors: Pimentel, G; Burton, KJ; von Ah, U; Bütikofer, U; Pralong, FP; Vionnet, N; Portmann, R; Vergères, G (2018) Journal of Nutrition 148:851-860. HERO ID: 4948162

[Less] Background: Fermentation is a widely used method of natural food preservation that . . . [More] Background: Fermentation is a widely used method of natural food preservation that has consequences on the nutritional value of the transformed food. Fermented dairy products are increasingly investigated in view of their ability to exert health benefits beyond their nutritional qualities.

Objective: To explore the mechanisms underpinning the health benefits of fermented dairy intake, the present study followed the effects of milk fermentation, from changes in the product metabolome to consequences on the human serum metabolome after its ingestion.

Methods: A randomized crossover study design was conducted in 14 healthy men [mean age: 24.6 y; mean body mass index (in kg/m2): 21.8]. At the beginning of each test phase, serum samples were taken 6 h postprandially after the ingestion of 800 g of a nonfermented milk or a probiotic yogurt. During the 2-wk test phases, subjects consumed 400 g of the assigned test product daily (200 g, 2 times/d). Serum samples were taken from fasting participants at the end of each test phase. The serum metabolome was assessed through the use of LC-MS-based untargeted metabolomics.

Results: Postprandial serum metabolomes after milk or yogurt intake could be differentiated [orthogonal projections to latent structures discriminant analysis (OPLS-DA) Q2 = 0.74]. Yogurt intake was characterized by higher concentrations of 7 free amino acids (including proline, P = 0.03), reduced concentrations of 5 bile acids (including glycocholic acid, P = 0.04), and modulation of 4 indole derivative compounds (including indole lactic acid, P = 0.01). Fasting serum samples after 2 wk of daily intake of milk or yogurt could also be differentiated based on their metabolic profiles (OPLS-DA Q2 = 0.56) and were discussed in light of the postprandial results.

Conclusion: Metabolic pathways related to amino acids, indole derivatives, and bile acids were modulated in healthy men by the intake of yogurt. Further investigation to explore novel health effects of fermented dairy products is warranted.This trial was registered at clinicaltrials.gov as NCT02230345.

Technical Report
Technical Report

G06 - Ames summary data: Diisodecyl phthalate (NTP study number: 926720)

Author: NTP (2018) HERO ID: 6392473


Technical Report
Technical Report

G06 - Ames summary data: Diisodecyl phthalate (NTP study number: 899698)

Author: NTP (2018) HERO ID: 6392476


Technical Report
Technical Report

G06 - Ames summary data: Diisononyl phthalate (NTP study number: 026376)

Author: NTP (2018) HERO ID: 6392477