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Chloroprene




  • 1.
    Book/Book Chapter
    Book/Book
    Chapter
    ß-Chloroprene

    Author: ACGIH
    (1991)
    Minus Sign. Click to see only selected choices. TLV Recommendation There are marked disparities between the dose-response and reported effects from . . . Plus Sign. Click to expand choices. TLV Recommendation There are marked disparities between the dose-response and reported effects from studies reported by U.S. and Russian investigators of the toxicity and hazards posed by exposure to chloroprene. The weight of both human and animal evidence for the carcinogenicity of chloroprene and for teratogenic and reproductive ef¬fects has to be considered as very limited or inadequate. The TLV Committee recommends aTLV-TWA of 10 ppm with a skin notation, based on the conclusion by von Oettingen and co-workers*4) that chloroprene probably can be absorbed through the skin in amounts sufficient to elicit acute effects. This TLV will protect exposed workers against the risk of systemic health effects. The TLV of 10 ppm for chloroprene Is equivalent to the TLV for 1,3-butadiene, a nonchlorinated analog of chloroprene. At this time, no STEL is recommended until additional toxicological data and industrial hygiene experience become available to provide a better base for quantifying on a toxicological basis what the STELshould be. The reader is encouraged to review the section on Excursion Limits in the "Introduction to the Chemical Substances" of the current TLV/BEI Booklet for guidance and control of excursions above the TLV-TWA, even when the 8-hour TWA is within the recommended limits.
    Tagged With: Not Cited

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  • 2.
    The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
    Peer
    Reviewed
    Journal
    Article
    A review of the epidemiology of 1,3-butadiene and chloroprene

    Authors: Acquavella, JF; Leonard, RC
    (2001) Chemico-Biological Interactions 135-136:43-52. [Review]
    Minus Sign. Click to see only selected choices. Butadiene epidemiologic research has focused primarily on one cohort of workers in the North American . . . Plus Sign. Click to expand choices. Butadiene epidemiologic research has focused primarily on one cohort of workers in the North American styrene-butadiene rubber (SBR) industry and on the largest cohort of workers in the United States butadiene monomer industry. The most recent studies of these populations are characterized by carefully enumerated study populations, extremely long and high quality mortality follow-up, accurate job categorizations, detailed exposure assessments, and comprehensive statistical analyses. Leukemia was clearly associated with increasing estimated butadiene exposure in the SBR study, but not in the monomer industry study. This has lead to hypotheses about exposure differences between these two industries and the presence of co-factors or confounders in the SBR industry. Research presented at this symposium should shed some light on these hypotheses. The chloroprene epidemiologic literature, on the other hand, is in an early stage of development. The existing studies are limited by poor exposure characterization, lack of control of potential confounding factors, incompleteness in cohort enumeration, short follow-up periods, and small numbers of cancer cases. The state of the science for chloroprene would be advanced by arranging more comprehensive studies than those that have been conducted to date.
    Tagged With: Cited 2010 Final - Appendix A Only, Not Cited
  • 3.
    The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
    Peer
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    Journal
    Article
    [Changes in the content of glycogen and its fractions in the brain of rats upon chloroprene poisoning]

    Author: Agadzhanov, MI
    (1966)
    Tagged With: Not Cited

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  • 4.
    The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
    Peer
    Reviewed
    Journal
    Article
    [The relationship of oxidation and phosphorylation in the mitochondria in the brain of rats poisoned with chloroprene]

    Author: Agadzhanov, MI
    (1966)
    Tagged With: Not Cited

    Details
       
  • 5.
    The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
    Peer
    Reviewed
    Journal
    Article
    [Changes in the ultrastructure of liver parenchymal cells in the rat in chloroprene toxicosis]

    Authors: Allaverdyan, AG; Manukyan, IA
    (1972)
    Tagged With: Not Cited

    Details
       
  • 6.
    The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
    Peer
    Reviewed
    Journal
    Article
    [Alopecia in a factory making polychloroprene elastomers]

    Authors: Amblard, P; Faure, J; Martel, J; Fillon, JP; Garna, A
    (1974) Bulletin de la Societe Francaise de Dermatologie et de Syphiligraphie 81:114-115.
    Tagged With: Cited 2009 Draft, Not Cited

    Details
       
  • 7.
    Journal Article
    Journal
    Article
    Study of the ozonolysis rate constants' dependence from the degree of oxidation of C-60 fullerene and trans-1,4-polychloroprene

    Authors: Anachkov, MP; Cataldo, F; Deneva, MG; Rakovski, SK
    (2007)
    Minus Sign. Click to see only selected choices. The changes in the current values of the reaction rate constants during the C-60 fullerene and polychloroprene . . . Plus Sign. Click to expand choices. The changes in the current values of the reaction rate constants during the C-60 fullerene and polychloroprene ozonolysis in solution have been investigated. The reaction has been conducted in a bubble reactor and the respective k values were determined on the basis of continuous measurement of the ozone concentration in the gas phase at the reactor outlet, under conditions of constant values of the ozone concentration at the reactor inlet. An effect of decrease in the current values of the rate constant during the conversion of the respective double bonds has been observed. It has been determined that the decrease Of C-60 fullerene k values in the 0-70% region of conversions is about 56%. In the case of polychloroprene the reduction is 18% and 24% at degree of conversion of 70% and 90% correspondingly. The mechanism of these effects and their influence on the rate constants dependences on the degree of conversion of the respective sp(2) C-C bonds have been considered. A supposition about the dominant role of the chemical factors on reduction of the current k values of the C-60 fullerene and polychloroprene has been substantiated.
    Tagged With: Not Cited
  • 8.
    The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
    Peer
    Reviewed
    Journal
    Article
    Kinetic and mechanistic data needs for a human phsiologically based pharmacokinetic (PBPK) model for acrylamide

    Authors: Andersen, ME; Scimeca, J; Olin, SS
    (2005) Advances in Experimental Medicine and Biology 561:117-125.
    Minus Sign. Click to see only selected choices. A pharmacokinetic (PBPK) model has been developed for acrylamide (AMD) and its oxidative metabolite, . . . Plus Sign. Click to expand choices. A pharmacokinetic (PBPK) model has been developed for acrylamide (AMD) and its oxidative metabolite, glycidamide (GLY), in the rat based on available information. Despite gaps and limitations to the database, model parameters have been estimated to provide a relatively consistent description of the kinetics of acrylamide and glycidamide using a single set of values (with minor adjustments in some cases). Future kinetic and mechanistic studies will need to focus on the collection of key data for refining certain model parameters and for model validation, as well as for conducting studies that elucidate the mechanism of action. Development of a validated human AMD/GLY PBPK model capable of predicting target tissue doses at relevant dietary AMD exposures, in combination with expanding data on modes of action, should allow for a substantive improvement in the risk assessment of acrylamide in food.
    Tagged With: Cited 2010 Final
  • 9.
    The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
    Peer
    Reviewed
    Journal
    Article
    [Biochemical changes in animals in studies of the embryotropic effect of synthetic chloroprene rubber wastes]

    Author: Apoyan, KK
    (1970)
    Tagged With: Not Cited

    Details
       
  • 10.
    The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
    Peer
    Reviewed
    Journal
    Article
    Spectrophotometric determination of chloroprene in air

    Authors: Apoyan KKh; Abeshyan, MM; Gofmekler, VA; Mnatsakanyan, AV; Mutafyan, GA; Pogosyan, UG; Tarverdyan AKh
    (1970)
    Tagged With: Not Cited

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