Health & Environmental Research Online (HERO)


Naphthalene


215 References Were Found:

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

[Monitoring and clinical treatment of naphthalene poisoning]

Authors: Cheng, WW; Kong, XL; Li, JL (2016) Zhonghua Laodong Weisheng Zhiyebing Zazhi / Chinese Journal of Industrial Hygiene and Occupational Diseases 34:391-392. HERO ID: 3453274


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

[Clinical analysis of five cases of acute naphthalene poisoning]

Authors: Yi, FF; Hao, YG; Qu, JL (2016) Zhonghua Laodong Weisheng Zhiyebing Zazhi / Chinese Journal of Industrial Hygiene and Occupational Diseases 34:695. HERO ID: 3453040


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

[Effect of 1,4-naphthoquinone aged black carbon on reactive oxygen species and DNA strand breaks in human bronchial epithelial cells]

Authors: Zhang, WX; Shang, J; Gao, X; Luan, XG; Li, P; Wang, TJ; Hu, GP; Zhu, T; Jia, G (2015) Beijing Daxue Xuebao (Yixue Ban) 47:690-696. HERO ID: 3452854

[Less] OBJECTIVE: To study the effect of 1,4-naphthoquinone aged black carbon (BC/1,4-NQ) . . . [More] OBJECTIVE: To study the effect of 1,4-naphthoquinone aged black carbon (BC/1,4-NQ) on reactive oxygen species and DNA strand breaks in human bronchial epithelial cells (16HBE).

METHODS: In the study, 16HBE cells were exposed to BC/1,4-NQ, BC and 1,4-NQ at the concentrations of BC/1,4-NQ (10.0/0.2, 20.0/0.4, 40.0/0.8, 80.0/1.6, 160.0/3.2 mg/L), BC (10.0, 20.0, 40.0, 80.0, 160.0 mg/L), 1,4-NQ (0.2, 0.4, 0.8, 1.6, 3.2 mg/L) for 24, 48, and 72 h, respectively. Cytotoxicity was detected by cell count kit 8 (CCK-8) at the end point. Then the 16HBE cells were exposed to BC/1,4-NQ (20.0/0.4, 40.0/0.8, 80.0/1.6 mg/L), BC (20.0, 40.0, 80.0 mg/L), 1,4-NQ (0.4, 0.8, 1.6 mg/L) for 24 h. The reactive oxygen species (ROS) generation was determined via flow cytometry with DCFH-DA probe. Single cell gel electrophoresis (SCGE) assay was performed to evaluate genotoxicity by Olive tail moment (OTM) value.

RESULTS: Except for the concentration of 10.0/0.2 mg/L within the exposure time 24 h, the cell viabilities of BC/1,4-NQ were significantly lower than the control (P<0.05) within the exposure time 24-72 h, showing a dose-dependent cytotoxicity. Especially, BC/1,4-NQ showed greater cytotoxicity than BC single exposure, lower than 1,4-NQ at the concentration of BC/1,4-NQ≥80.0/1.6 mg/L. BC/1,4-NQ also showed greater ROS generation and OTM value than the control within the exposure time 24 h at each concentration (P<0.05). Especially, the ROS generation and OTM value of BC/1,4-NQ were greater than BC single exposure, lower than 1,4-NQ at the concentration of 80.0/1.6 mg/L (P<0.05).

CONCLUSION: BC/1,4-NQ can induce intracellular ROS generation, cytotoxicity and genotoxicity in 16HBE cells. And at high concentration, the intracellular ROS level, cytotoxicity and genotoxicity induced by BC/1,4-NQ were greater than those by BC single exposure, but lower than those by 1,4-NQ.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Considering Mutagenicity and Genotoxicity in the Cancer Mode-of-Action for Naphthalene, Styrene and Ethylbenzene

Authors: Keshava, N; Woodall, G; Keshava, C; Reinhart, P (2013) HERO ID: 2711743


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Experimental Study to Evaluate Protective Effects of Naproxen and Celecoxib on Naphthalene induced Cataract in Albino Rats

Authors: Khadka, A; Brashier, DBS; Sharma, AK (2013) HERO ID: 2711744


Technical Report
Technical Report

Submission of Toxicity Data in Support of the Registration Review of Naphthalene. Transmittal of 1 Study

Author: Rechochem, I (2012) (MRID 48792700). HERO ID: 3056824


Technical Report
Technical Report

Naphthalene: 4 Week Oral Gavage Immunotoxicity Study in the Female CD 1 Mouse. Project Number: MCW0027. Unpublished study prepared by Huntingdon Life Sciences, Ltd. 143p

Author: Chambers, P (2012) (MRID 48792701). HERO ID: 3056825


The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

H-1 NMR metabolomics of earthworm responses to sub-lethal PAH exposure

Authors: Brown, SAE; Simpson, AJ; Simpson, MJ (2009) HERO ID: 1487686

[Less] Metabolic responses of earthworm exposure to the polycyclic aromatic hydrocarbons (PAHs) naphthalene, . . . [More] Metabolic responses of earthworm exposure to the polycyclic aromatic hydrocarbons (PAHs) naphthalene, phenanthrene and pyrene in contact tests were measured using H-1 nuclear magnetic resonance (NMR). Novel metabolites were not detected but principal component analysis (PCA) showed that earthworms exposed to 10, 50 and 100 mu g cm(-2) naphthalene, phenanthrene and pyrene differed from unexposed (control) earthworms. Partial least-squares-discriminant analysis (PLS-DA) showed that earthworms had statistically significant responses to PAH exposure, except for 10 mu g cm(-2) naphthalene and 50 mu g cm(-2) pyrene. Leucine, valine, alanine, lysine and maltose were identified as potential response indicators of PAH exposure, but whether the concentration of these metabolites increased or decreased was PAH- and concentration-dependent. These initial findings reveal the potential of metabolomics for monitoring earthworm responses to sub-lethal PAH exposure and highlight the role of metabolomics as a future tool in ecotoxicology.

The "refereed" or "peer review" status of a journal comes from the Ulrichsweb Global Serials Directory (http://ulrichsweb.serialssolutions.com/), as supplied by the publisher. The term refers to the system of critical evaluation of manuscripts/articles by professional colleagues or peers. The content of refereed publications is sanctioned, vetted, or otherwise approved by a peer-review or editorial board. The peer-review and evaluation system is utilized to protect, maintain, and raise the quality of scholarly material published in serials. Publications subject to the referee process are assumed, then, to contain higher quality content than those that are not.
Peer Reviewed Journal Article

Importance of microsomal epoxide hydrolase (mEH) in toxicity, metabolism and formation of covalent protein adducts from the volatile air pollutant, naphthalene (NA): Comparison of mEH null and wild type (WT) mice

Authors: Krawiec, DM; Sutherland, K; Morin, D; Thornton, J; Buckpitt, A; Van Winkle, L (2008) FASEB Journal 22. HERO ID: 1493906

[Less] Human exposure to NA is due to combustion of both environmental and man-made materials. Toxicity of . . . [More] Human exposure to NA is due to combustion of both environmental and man-made materials. Toxicity of NA is P450-dependent, occurring in murine, but not rat, airways. However, the extent to which specific metabolic pathways (to epoxides, quinones and diol epoxides) contribute to cytotoxicity and the formation of covalent protein adducts is unknown. Upon inhalation exposure to NA (4h at 5–20 ppm) male mEH null animals had increased cytotoxicity in the bronchioles, but decreased susceptibility in the trachea and lobar bronchus as compared to WT mice, despite having a normal pattern of P450-containing CC10 positive Clara cells. Formation rates of NA metabolites (conjugates plus diol) in the trachea were lower in EH null animals, but equivalent in the airways compared to WT. As expected, rates of diol formation were undetected/low in mEH null animals. Protein adducts detected after ip administration of NA were 2–4 fold higher in airway epithelium than elsewhere in the lung, and EH null animals showed significantly higher levels compared to WT. Bound liver adducts showed no differences between mEH and WT animals. These studies suggest that metabolites (1,2-quinone, diol epoxide) arising via the diol pathway are not critical to NA toxicity or formation of covalent adducts in distal airway epithelium. This work also suggests that there are compensatory changes associated with disruption of mEH.

Book/Book Chapter
Book/ Chapter

Population screening-level risk assessment of nasal tumors due to naphthalene exposure

Authors: Magee, B; Chappel, M; Haines, K; Longoni, G; Livio, S (2008) In ConSoil 2008 : proceedings of the 10th international UFZ-Deltares/TNO conference on soil-water systems in cooperation with Provincia di milano (pp. 344-351). Leipzig, Germany: UFZ. HERO ID: 1489482