A new griseofulvin derivative from a soft coral-derived fungus Eupenicillium sp. SCSIO41208
Authors: Li, Y; Tan, Y; Liu, J; Zhou, X; Zeng, S; Dong, J; Liu, Y; Yang, B
Natural Product Research 1-5.
HERO ID: 5092895
A new griseofulvin derivative, eupenigriseofulvin (1), together with six known compounds, griseofulvin . . .
A new griseofulvin derivative, eupenigriseofulvin (1), together with six known compounds, griseofulvin (2), dechlorogriseofluvin (3), dechloroisogriseofulvin (4), trichopyrone (5), 2-(4-hydroxyphenyl)-ethanol (6), and 1-phenylethane-1,2-diol (7), were isolated from the EtOAc extract of Eupenicillium sp. SCSIO41208. The structures of these compounds were elucidated by spectroscopic methods including NMR and mass spectrometry. The absolute configuration of 1 was determined on the basis of electronic circular dichroism (ECD) data analysis.