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Citation
Tags
HERO ID
1025317
Reference Type
Journal Article
Title
Mutual interaction between nutritional status and chronic arsenic toxicity due to groundwater contamination in an area of Terai, lowland Nepal
Author(s)
Maharjan, M; Watanabe, C; Ahmad, SA; Umezaki, M; Ohtsuka, R
Year
2007
Is Peer Reviewed?
Yes
Journal
Journal of Epidemiology and Community Health
ISSN:
0143-005X
EISSN:
1470-2738
Volume
61
Issue
5
Page Numbers
389-394
Language
English
PMID
17435204
DOI
10.1136/jech.2005.045062
Web of Science Id
WOS:000245685800007
Abstract
OBJECTIVE:
To reveal the inter-relationship between nutritional status and arsenic toxicity.
DESIGN:
Cross-sectional study.
SETTING:
A survey in an area of lowland Nepal, where a high prevalence of both skin manifestation and malnutrition was observed. Daily arsenic intake was estimated by measuring the arsenic concentration and daily consumption of the drinking water.
PARTICIPANTS:
Adult villagers (248 men and 291 women). About half were classified as "underweight" (body mass index <18.5), indicating poor nutritional status.
MAIN RESULTS:
Arsenic intake was negatively correlated with body mass index and substantially increased the prevalence of underweight individuals, among whom the prevalence of skin manifestations was 1.65-fold higher than normal weight individuals. When exposure level was considered, the prevalence of skin symptoms was consistently higher in the underweight than in the normal group. Although enhanced susceptibility in men was apparent by the increased prevalence of cutaneous symptoms, no sex difference was observed in the prevalence of underweight individuals related with exposure to arsenic.
CONCLUSIONS:
The present data suggested that exposure to arsenic is associated with an increased prevalence of underweight, a serious health problem in developing countries, which in turn is associated with increased skin manifestation of arsenic poisoning.
Tags
•
Arsenic Hazard ID
1. Initial Lit Search
PubMed
WOS
ToxNet
4. Considered through Oct 2015
8. Hazard through Oct 2015
Epi Hazard ID
Not Relevant
Susceptibility Category
Nutritional Deficiencies (includes socioeconomic status & BMI)
•
Arsenic (Inorganic)
1. Literature
PubMed
Toxline, TSCATS, & DART
Web of Science
3. Hazard ID Screening
Potentially relevant epidemiology studies
5. Susceptibility Screening
Relevant
Human
Cited in Volume 2a
Cited in Volume 2b
•
Arsenic Susceptibility
4. Susceptibility and Lifestages
Nutritional deficiencies (includes socioeconomic status and BMI)
5. Health Effect
Skin Diseases
1. Susceptibility Literature Screening
Keyword Search
Life Stages Citation Mapping
5%-10%
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