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Citation
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HERO ID
1070379
Reference Type
Journal Article
Title
Comparative transcriptome analysis of transporters, phytohormone and lipid metabolism pathways in response to arsenic stress in rice (Oryza sativa)
Author(s)
Yu, L-J; Luo, Y-F; Liao, B; Xie, L-J; Chen, L; Xiao, S; Li, J-T; Hu, S-N; Shu, W-S
Year
2012
Is Peer Reviewed?
1
Journal
New Phytologist
ISSN:
0028-646X
EISSN:
1469-8137
Volume
195
Issue
1
Page Numbers
97-112
Language
English
PMID
22537016
DOI
10.1111/j.1469-8137.2012.04154.x
Web of Science Id
WOS:000304448500014
URL
http://doi.wiley.com/10.1111/j.1469-8137.2012.04154.x
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Abstract
• Arsenic (As) contamination of rice (Oryza sativa) is a worldwide concern and elucidating the molecular mechanisms of As accumulation in rice may provide promising solutions to the problem. Previous studies using microarray techniques to investigate transcriptional regulation of plant responses to As stress have identified numerous differentially expressed genes. However, little is known about the metabolic and regulatory network remodelings, or their interactions with microRNA (miRNA) in plants upon As(III) exposure. • We used Illumina sequencing to acquire global transcriptome alterations and miRNA regulation in rice under As(III) treatments of varying lengths of time and dosages. • We found that the response of roots was more distinct when the dosage was varied, whereas that of shoots was more distinct when the treatment time was varied. In particular, the genes involved in heavy metal transportation, jasmonate (JA) biosynthesis and signaling, and lipid metabolism were closely related to responses of rice under As(III) stress. Furthermore, we discovered 36 new As(III)-responsive miRNAs, 14 of which were likely involved in regulating gene expression in transportation, signaling, and metabolism. • Our findings highlight the significance of JA signaling and lipid metabolism in response to As(III) stress and their regulation by miRNA, which provides a foundation for subsequent functional research.
Keywords
Arsenic; heavy metal transporter; jasmonate signaling; lipid metabolism; mRNA and microRNA sequencing; Oryza sativa
Tags
•
Arsenic Hazard ID
1. Initial Lit Search
PubMed
WOS
ToxNet
WOS
Considered New
2. Lit Search Updates through Oct 2015
WOS
Considered
4. Considered through Oct 2015
6. Cluster Filter through Oct 2015
7. Other Studies through Oct 2015
Ecology
iAs MOA Literature Categorization
Epigenetic Mechanisms
•
Arsenic (Inorganic)
1. Literature
PubMed
Toxline, TSCATS, & DART
Web of Science
Lit search updates through Oct 2015
3. Hazard ID Screening
Other potentially supporting studies
4. Adverse Outcome Pathways/Networks Screening
Excluded/Not relevant
Title/Abstract screening
•
Arsenic MOA
1. MOA Literature Screening
MOA Cluster
3. Excluded
Other not relevant
Dragon Screened
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