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Citation
Tags
HERO ID
11260
Reference Type
Journal Article
Title
Transplacental passage of dichloromethane and carbon monoxide
Author(s)
Anders, MW; Sunram, JM
Year
1982
Is Peer Reviewed?
1
Journal
Toxicology Letters
ISSN:
0378-4274
EISSN:
1879-3169
Report Number
ETICBACK/28372
Book Title
Toxicol. Lett.
Volume
12
Issue
4
Page Numbers
231-234
Language
English
PMID
7135421
DOI
10.1016/0378-4274(82)90245-4
Web of Science Id
WOS:A1982PG18700002
URL
http://
://WOS:A1982PG18700002
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Abstract
Maternal blood dichloromethane concentrations were higher than fetal blood dichloromethane concentrations and maternal and fetal blood carbon monoxide concentrations were the same in pregnant rats exposed to 500 ppm of dichloromethane. Fetal blood carbon monoxide concentrations were higher than maternal blood carbon monoxide concentrations in pregnant rats exposed to 20 ppm of carbon monoxide. These results show that maternal exposure to dichloromethane is accompanied by fetal exposure to both dichloromethane and carbon monoxide.
Tags
IRIS
•
DCM (Dichloromethane) (Final, 2011)
•
Formaldehyde
Reproductive and Developmental Effects
Screened
Title/abstract
Not formaldehyde
Retroactive RIS import
2015
FA DevRepro 072115
Not FA-Exposure Criteria
Not FA-Exposure Criteria
OPPT REs
•
OPPT_Methylene Chloride_F. Human Health
Total – title/abstract screening
On topic
Peer review
Primary source
Cited in IRIS document or IRIS HERO page
On topic - additional tags for titles/abstracts
ADME
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