Exploration of the composition and sources of urban fine particulate matter associated with same-day cardiovascular health effects in Dearborn, Michigan | Health & Environmental Research Online (HERO)

Health & Environmental Research Online (HERO)

Print Feedback Export to File

This record has one attached file:

Citation
Tags

HERO ID

2520278

Reference Type

Journal Article

Title

Exploration of the composition and sources of urban fine particulate matter associated with same-day cardiovascular health effects in Dearborn, Michigan

Author(s)

Morishita, M; Bard, RL; Kaciroti, N; Fitzner, CA; Dvonch, T; Harkema, JR; Rajagopalan, S; Brook, RD

Year

2015

Is Peer Reviewed?

Journal

Journal of Exposure Science & Environmental Epidemiology
ISSN: 1559-0631
EISSN: 1559-064X

Volume

Issue

Page Numbers

145-152

Language

English

PMID

24866265

DOI

10.1038/jes.2014.35

Web of Science Id

WOS:000349741600003

Relationship(s)

is supplemented by 3859198 - Supplementary material

Abstract

The objective was to explore associations of chemical components and source factors of ambient fine particulate matter (aerodynamic diameter ≤2.5 μm; PM2.5) with cardiovascular (CV) changes following same-day exposure to ambient PM2.5. Twenty-five healthy adults living in rural Michigan were exposed to ambient air in an urban/industrial community for 4 to 5 h daily for five consecutive days. CV health outcomes were measured 1-2 h post exposure. Contributing emission sources were identified via positive matrix factorization. We examined associations between PM2.5 mass, composition and source factors, and same-day changes in CV outcomes using mixed-model analyses. PM2.5 mass (10.8±6.8 μg/m(3)), even at low ambient levels, was significantly associated with increased heart rate (HR). Trace elements as well as secondary aerosol, diesel/urban dust and iron/steel manufacturing factors potentially explained the HR changes. However, trace element analysis demonstrated additional associations with other CV responses including changes in blood pressure (BP), arterial compliance, autonomic balance and trends toward reductions in endothelial function. Two factors were related to BP changes (diesel/urban dust, motor vehicle) and trends toward impaired endothelial function (diesel/urban dust). This study indicates composition of PM2.5 and its sources may contribute to CV health effects independently of PM2.5 mass.Journal of Exposure Science and Environmental Epidemiology advance online publication, 28 May 2014; doi:10.1038/jes.2014.35.

Keywords

PM2.5; Dearborn; cardiovascular effects; receptor modeling