Jump to main content
US EPA
United States Environmental Protection Agency
Search
Search
Main menu
Environmental Topics
Laws & Regulations
About EPA
Health & Environmental Research Online (HERO)
Contact Us
Print
Feedback
Export to File
Search:
This record has one attached file:
Add More Files
Attach File(s):
Display Name for File*:
Save
Citation
Tags
HERO ID
2718068
Reference Type
Journal Article
Title
Analysis of PAEs in semen of infertile men
Author(s)
Wang, SY; Wang, Y; Xie, FQ; Li, YX; Wan, XL; Ma, WW; Wang, DC; Wu, YH
Year
2015
Is Peer Reviewed?
Yes
Journal
International Journal of Occupational and Environmental Health
ISSN:
1077-3525
EISSN:
2049-3967
Volume
21
Issue
1
Page Numbers
40-48
Language
English
PMID
25384258
DOI
10.1179/2049396714Y.0000000088
Web of Science Id
WOS:000349143700006
Abstract
Objectives: Phthalates are environmental chemicals with reproductive toxicity and estrogenic effects in animals. They are of increasing concern to human health. Aim: To determine whether phthalate levels in semen were associated with infertility. Methods: Using semen samples from 107 infertile and 94 fertile men, the presence and quantity of five phthalate esters were measured using high-performance liquid chromatography (HPLC). Using data collected from questionnaires and clinical examinations, the correlation between phthalate exposure and semen quality was analyzed. Results: The cumulative levels of the measured phthalate esters were significantly higher in the infertility group compared to the control group (P<0·05). Concentrations of the five phthalate esters in men varied by age with older men showing higher cumulative levels. Conclusions: The presence of phthalates may contribute to male infertility in our study population.
Keywords
Male infertility; Semen; Phthalates; High-performance liquid chromatography
Tags
IRIS
•
Dibutyl Phthalate (DBP)
Database Searches
LitSearch Jul 2016 - Jan 2017
Considered new
WoS
•
Phthalates – Targeted Search for Epidemiological Studies
Source – all searches
Pubmed
WOS
Included
DEHP
DBP
BBP
DEP
Source – Dec 2014 Update (Private)
Pubmed
Source – Mar 2015 Update (Private)
Pubmed
WOS
Source – Dec 2015 Update (Private)
WOS
Source - Jun 2016 Update (Private)
WOS
Source - Dec 2016 Update (Private)
Pubmed
Home
Learn about HERO
Using HERO
Search HERO
Projects in HERO
Risk Assessment
Transparency & Integrity