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2849943 
Journal Article 
The carbomethylation of arylacrylamides leading to 3-ethyl-3-substituted indolin-2-one by cascade radical addition/cyclization 
Dai, Q; Yu, J; Jiang, Y; Guo, S; Yang, H; Cheng, J 
2014 
Yes 
Chemical Communications
ISSN: 1359-7345
EISSN: 1364-548X 
50 
29 
3865-3867 
English 
24589915 
An FeCl2-promoted carbomethylation of arylacrylamides by di-tert-butyl peroxide (DTBP) is achieved, leading to 3-ethyl-3-substituted indolin-2-one in high yield. The reaction tolerates a series of functional groups, such as cyano, nitro, ethyloxy carbonyl, bromo, chloro, and trifluoromethyl groups. The radical methylation and arylation of the alkenyl group are involved in this reaction.