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2857047 
Journal Article 
Review 
Neurotoxicity of toluene 
Win-Shwe, T-T; Fujimaki, H 
2010 
1 
Toxicology Letters
ISSN: 0378-4274
EISSN: 1879-3169 
198 
2 
93-99 
English 
20599484 
Chemical susceptibility is triggered by a large range of chemicals present both indoors and outdoors including pesticides, cleaning products, perfumes, scented products and cigarette smoke. Health risk after chemical exposure depends on age, sex, genetic factors, socioeconomic status, nutritional status, and environmental factors. Toluene is one of volatile organic chemicals that causes different sensitivity in individuals. Although neurotoxic and immunotoxic effects of toluene have been studied extensively, the underlying mechanism remains obscure. This review highlights the possible neuroimmune factors influencing toluene sensitivity and neurotoxicity in a mouse model.