Jump to main content
US EPA
United States Environmental Protection Agency
Search
Search
Main menu
Environmental Topics
Laws & Regulations
About EPA
Health & Environmental Research Online (HERO)
Contact Us
Print
Feedback
Export to File
Search:
This record has one attached file:
Add More Files
Attach File(s):
Display Name for File*:
Save
Citation
Tags
HERO ID
3035884
Reference Type
Journal Article
Title
Acute haemolytic anaemia and myolysis due to G6PD deficiency
Author(s)
Mangat, C; Inoue, S; Saah, E; Sharman, M
Year
2014
Is Peer Reviewed?
1
Journal
BMJ Case Reports
EISSN:
1757-790X
Volume
2014
Language
English
PMID
25234071
DOI
10.1136/bcr-2014-203631
Abstract
A 2-year-old African-American male patient with sickle cell trait developed cough, red coloured urine, pallor and fatigue. The patient was hospitalised. Diagnostic workup showed that he was glucose 6 phosphate dehydrogenase (G6PD) deficient in erythrocytes. He also had chest X-ray findings of pneumonia. His urine examination showed the presence of haemoglobin and myoglobin. On repeated questioning it was found that he had a moth ball in his mouth a few days prior to this medical episode. This case illustrates a rarely described complication of myolysis in G6PD deficient persons on exposure to a strong oxidant. A review of the literature showed that most people with G6PD deficiency tolerate exercise well without untoward effect in muscles. However, assay of myoglobin in urine has not been routinely performed in these patients during acute haemolytic episode, and thus it is uncertain how frequent myoglobulinaemia occurs in a similar stress situation.
Tags
IRIS
•
Naphthalene
Database Searches - Nov 2015 (private)
New Nov 2015 (private)
Database Searches
PubMed
Combined data set
Data set for title/abstract screening
Data set for full text review
Excluded – PECO criteria not met (full-text)
Supplemental material
Case reports/Case series
Mechanistic
Mechanisms of hemolysis
Other
•
Naphthalene (2021 Evidence mapping publication)
Database Searches - Nov 2015 (private)
New Nov 2015 (private)
Database Searches
PubMed
Combined data set
Data set for title/abstract screening
Data set for full text review
Excluded – PECO criteria not met (full-text)
Supplemental material
Case reports/Case series
Mechanistic
Mechanisms of hemolysis
Home
Learn about HERO
Using HERO
Search HERO
Projects in HERO
Risk Assessment
Transparency & Integrity