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HERO ID
3216490
Reference Type
Journal Article
Title
Advanced interatrial block predicts clinical recurrence of atrial fibrillation after catheter ablation
Author(s)
Wu, JT; Long, DY; Dong, JZ; Wang, SL; Fan, XW; Yang, HT; Duan, HY; Yan, LJ; Qian, P; Yang, CK
Year
2015
Is Peer Reviewed?
Yes
Journal
Journal of Cardiology
ISSN:
0914-5087
Language
English
PMID
26611936
DOI
10.1016/j.jjcc.2015.10.015
Abstract
BACKGROUND:
It has been demonstrated that advanced interatrial block (IAB) is associated with an increased risk of atrial fibrillation (AF); however, the impact of advanced IAB on recurrence of paroxysmal AF after catheter ablation is not clear.
METHODS:
204 consecutive patients with paroxysmal AF who underwent index circumferential pulmonary vein (PV) isolation were prospectively enrolled. In all patients, a resting electrocardiogram in sinus rhythm was evaluated for the presence of advanced IAB, defined as a P-wave duration >120ms and biphasic (±) morphology in the inferior leads. Advanced IAB was detected in 20.1% of patients. AF recurrence was defined as the occurrence of confirmed atrial tachyarrhythmia lasting more than 30s beyond 3 months after the catheter ablation in the absence of any antiarrhythmic treatment.
RESULTS:
During the mean follow-up period of 13.9±6.2 months (range, 3-27 months), 62 patients (30.4%) developed recurrence of AF. The recurrence rate was higher in patients with advanced IAB than those without advanced IAB (46.3% vs. 26.4%, p=0.006). Cox regression analysis with adjustment for age, P-wave duration, CHADS2 score, and PV isolation identified advanced IAB (hazard ratio, 2.111; 95% confidence interval, 1.034-4.308; p=0.040) and left atrial diameter (hazard ratio, 1.051; 95% confidence interval, 1.004-1.100; p=0.034) as two independent predictors of recurrence of AF.
CONCLUSIONS:
Patients with advanced IAB were at an increased risk of AF recurrence after catheter ablation.
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