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Citation
Tags
HERO ID
3350260
Reference Type
Journal Article
Subtype
Review
Title
Influence of Lipophilicity on the Toxicity of Bisphenol A and Phthalates to Aquatic Organisms
Author(s)
Mathieu-Denoncourt, J; Wallace, SJ; de Solla, SR; Langlois, VS
Year
2016
Is Peer Reviewed?
Yes
Journal
Bulletin of Environmental Contamination and Toxicology
ISSN:
0007-4861
EISSN:
1432-0800
Publisher
SPRINGER
Location
NEW YORK
Volume
97
Issue
1
Page Numbers
4-10
Language
English
PMID
27169527
DOI
10.1007/s00128-016-1812-9
Web of Science Id
WOS:000378779300003
Abstract
Bisphenol A (BPA) and phthalates are among the most popular plasticizers used today and have been reported ubiquitously in surface water, ground water, and sediment. For aquatic organisms, BPA was the most toxic (96 h LC50s) to aquatic invertebrates (0.96-2.70 mg/L) and less toxic to fish (6.8-17.9 mg/L). The toxicity of BPA to amphibians differed among developmental stages, with embryos having an LC50 of 4.6-6.8 mg/L and juveniles 0.50-1.4 mg/L. The toxicity of phthalates is affected by aromatic ring substitution, alkyl chain length, and metabolism. The toxicity (96 h LC50s) of phthalates was similar to aquatic invertebrates (0.46-377 mg/L) and fish (0.48-121 mg/L). In general, the toxicity of phthalates appears to be highest around a log KOW of 6, which corresponds to the highest potential for bioconcentration and bioaccumulation. In conclusion, the lipophilicity of BPA and phthalates influence their toxicity to aquatic species.
Tags
IRIS
•
BBP (Butyl benzyl phthalate)
Literature Search
Literature Search: July 2016 - January 2017
WOS
Excluded: No Primary Data on Health Effects
Ecosystem effects
•
Dibutyl Phthalate (DBP)
Database Searches
Litsearch Jan 2016 - July 2016
Pubmed
Excluded: No Primary Data on Health Effects
Ecosystem effects
•
Diethyl phthalate (DEP)
Database searches
Jan 2017 update
Considered new
Web of Science
Jan 2020 update
Web of Science
Excluded: No Primary Data on Health Effects
Ecosystem effects
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