Jump to main content
US EPA
United States Environmental Protection Agency
Search
Search
Main menu
Environmental Topics
Laws & Regulations
About EPA
Health & Environmental Research Online (HERO)
Contact Us
Print
Feedback
Export to File
Search:
This record has one attached file:
Add More Files
Attach File(s):
Display Name for File*:
Save
Citation
Tags
HERO ID
3350478
Reference Type
Journal Article
Title
Dataset of liver proteins changed in eu- and hypothyroid female rats upon in vivo exposure to hexabromocyclododecane (HBCD)
Author(s)
Miller, I; Serchi, T; Cambier, S; Diepenbroek, C; Renaut, J; van den Berg, JH; Kwadijk, C; Gutleb, AC; Rijntjes, E; Murk, AJ
Year
2016
Is Peer Reviewed?
Yes
Volume
7
Page Numbers
386-392
Language
English
PMID
26977443
DOI
10.1016/j.dib.2016.02.047
Abstract
Female Wistar rats with different thyroid status (eu-, hypothyroid) were exposed to 0, 3 or 30 mg/kg body weight of the flame retardant HBCD for 7 days. Changes in protein patterns obtained by 2D-DIGE were evaluated, and different animal groups compared taking into account their exposure and thyroid status. Proteins significantly altered in abundance in any of these comparisons were identified by mass spectrometry. These data, together with hormone data of the animals, are discussed in "Hexa-bromocyclododecane (HBCD) induced changes in the liver proteome of eu- and hypothyroid female rats" (Miller et al., 2016) [1].
Tags
IRIS
•
Hexabromocyclododecane (HBCD)
New 7/2016 (private)
Database Searches
Pubmed
Other Sources of Supplementary Health Effects Data
Acute/short-term animal studies
OPPT REs
•
OPPT_Cyclic Aliphatic Bromine Cluster (HBCD)_F. Human Health
Total – title/abstract screening
On topic
Peer review
Primary source
Cited in IRIS document or IRIS HERO page
On topic - additional tags for titles/abstracts
Animal hazard ID
MOA
Home
Learn about HERO
Using HERO
Search HERO
Projects in HERO
Risk Assessment
Transparency & Integrity