US EPA

3455008 

Journal Article 

Supplemental Data 

Exposure to phthalates in house dust and associated allergies in children aged 6-12 years 

Ait Bamai, Y; Araki, A; Kawai, T; Tsuboi, T; Saito, I; Yoshioka, E; Cong, S; Kishi, R 

2016 

1 

Environment International
ISSN: 0160-4120
EISSN: 1873-6750 

Elsevier 

96 

Elsevier 

16-23 

English 

27588698 

10.1016/j.envint.2016.08.025 

WOS:000386933300003 

https://linkinghub.elsevier.com/retrieve/pii/S0160412016303233
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Phthalates are widely used as plasticizers in household products. Several studies have reported an association between phthalate exposure and an increased risk of allergies. The present study estimated phthalate exposure in children aged 6-12years and assessed potential correlations with allergies. House dust samples were collected from floors and multi-surface objects >35cm above the floor. Urine samples were collected from the first morning void of the day. Daily phthalate intake (DIdust and DI) was estimated using both house dust and urinary metabolite concentrations. Exposure to di-2-ethylhexyl phthalate (DEHP) in floor dust was associated with parental-reported rhino-conjunctivitis. After stratification by gender, this trend was found to only occur in boys. Furthermore, urinary mono-isobutyl phthalate was inversely associated with parental-reported wheeze in boys. DIdust of benzyl butyl phthalate (BBzP) and DEHP were significantly correlated with DI_BBzP and DI_DEHP, respectively. These correlations were stronger with floor than with multi-surface dust. Our results suggest that, among Japanese children, house dust from low surfaces, such as living room floors, might play a meaningful role in the indoor environmental exposure pathway for BBzP and DEHP. 

Allergy; Daily intake; House dust; Phthalates; Urinary metabolites