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Citation
Tags
HERO ID
3469538
Reference Type
Journal Article
Subtype
Review
Title
The effects of phthalates in the cardiovascular and reproductive systems: A review
Author(s)
Mariana, M; Feiteiro, J; Verde, I; Cairrao, E
Year
2016
Is Peer Reviewed?
1
Journal
Environment International
ISSN:
0160-4120
EISSN:
1873-6750
Publisher
Elsevier Ltd
Location
OXFORD
Volume
94
Page Numbers
758-776
Language
English
PMID
27424259
DOI
10.1016/j.envint.2016.07.004
Web of Science Id
WOS:000382339000085
URL
http://
://WOS:000382339000085
Exit
Abstract
Every year millions of tons of plastic are produced around the world and humans are increasingly exposed to them. This constant exposure to plastics has raised some concerns against human health, particularly when it comes to phthalates. These compounds have endocrine-disrupting properties, as they have the ability to bind molecular targets in the body and interfere with hormonal function and quantity. The main use of phthalates is to give flexibility to polyvinyl chloride (PVC) polymers. Phthalates are found in a variety of industrial and consumer products, and as they are not covalently bound to the plastic, phthalates contaminate the environment from which human exposure occurs. Studies in human and animal populations suggest a correlation between phthalate exposure and adverse health outcomes, particularly at the reproductive and cardiovascular systems, however there is much less information about the phthalate toxicity of the later. Thus, the main purpose of this review is to present the studies relating the effects already stated of phthalates on the cardiovascular and reproductive systems, and also present the link between these two systems.
Keywords
Cardiotoxicity; Endocrine-disrupting compounds; Human health; Phthalates; Plastics; Reproductive toxicity
Tags
IRIS
•
BBP (Butyl benzyl phthalate)
Additional Search Strategies
March 2017 Search strategy results
Secondary Literature
Reviews/editorials
•
Dibutyl Phthalate (DBP)
Database Searches
LitSearch Jul 2016 - Jan 2017
Considered new
WoS
•
Diethyl phthalate (DEP)
Additional Strategies
March 2017 Search strategy results
Secondary Literature
Reviews and Editorials
•
Diisononyl Phthalate (DINP)
Additional Search Strategies
March 2017 Search strategy results
Secondary Literature
Reviews/editorials
•
Phthalates – Targeted Search for Epidemiological Studies
Source – all searches
Pubmed
WOS
Excluded
Source - Dec 2016 Update (Private)
Pubmed
WOS
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