US EPA

3491055 

Journal Article 

Synthesis of molecularly imprinted polymers by atom transfer radical polymerization for the solid-phase extraction of phthalate esters in edible oil 

Human Exposure Laboratory :: HEL 

2017 

Yes 

Journal of Separation Science
ISSN: 1615-9306
EISSN: 1615-9314 

WILEY-V C H VERLAG GMBH 

WEINHEIM 

40 

6 

1327-1333 

English 

28058766 

10.1002/jssc.201601108 

WOS:000397830200012 

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85012894483&doi=10.1002%2fjssc.201601108&partnerID=40&md5=4e40d2ad1a05b62c2ae9d8fe002608a8
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Novel molecularly imprinted polymers of phthalate esters were prepared by atom transfer radical polymerization using methyl methacrylate as functional monomer, cyclohexanone as solvent, cuprous chloride as catalyst, 1-chlorine-1-ethyl benzene as initiator and 2,2-bipyridyl as cross-linker in the mixture of methanol and water (1:1, v/v). The effect of reaction conditions such as monomer ratio and template on the adsorption properties was investigated. The optimum condition was obtained by an orthogonal experiment. The obtained polymers were characterized using scanning electron microscopy. The binding property was studied with both static and dynamic methods. Results showed that the polymers exhibited excellent recognition capacity and outstanding selectivity for ten phthalate esters. Factors affecting the extraction efficiency of the molecularly imprinted solid-phase extraction were systematically investigated. An analytical method based on the molecularly imprinted coupled with gas chromatography and flame ionization detection was successfully developed for the simultaneous determination of ten phthalate esters from edible oil. The method detection limits were 0.10-0.25 μg/mL, and the recoveries of spiked samples were 82.5-101.4% with relative standard deviations of 1.24-5.37% (n = 6). This article is protected by copyright. All rights reserved. 

atom transfer radical polymerization; edible oils; molecularly imprinted polymers; phthalate esters