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Citation
Tags
HERO ID
3859201
Reference Type
Journal Article
Title
Assessing solvent derivatization and carbon dioxide supercritical fluid simultaneous extraction/derivatization of cyprodinil
Author(s)
Aguilera, A; Valverde, A; Valverde-Monterreal, A; Garcia-Fuentes, L; Boulaid, M
Year
2014
Is Peer Reviewed?
Yes
Journal
Journal of Environmental Science and Health, Part B: Pesticides, Food Contaminants, and Agricultural Wastes
ISSN:
0360-1234
EISSN:
1532-4109
Publisher
Taylor and Francis Inc.
Volume
49
Issue
8
Page Numbers
541-549
Language
English
PMID
24901957
DOI
10.1080/03601234.2014.911553
Web of Science Id
WOS:000337963100001
Abstract
Derivatization of cyprodinil with different reagents and solvents has been evaluated to improve the GC/MS characterization of this fungicide. After assessing some preliminary acylation and silylation reactions, derivatization with anhydrous heptafluorobutyric anhydride (HFBA) was selected as the best derivatization option for cyprodinil. The HFBA-cyprodinil derivative was clearly identified and characterized by GC/MS (ion-trap). The spectrum of the HFBA derivative of cyprodinil was characterized by the base peak, 252 m/z ion, and two other ions with relative abundances of 5% (224 m/z ion) and 4% (420 m/z molecular ion). Conversion rates in the range of 83-92% were obtained when 0.1-1 μg cyprodinil were derivatized in vial without solvent at 25ºC temperature for 120 min, with 5 μL HFBA and 5 μL pyridine. Simultaneous extraction-derivatization of cyprodinil in supercritical carbon dioxide was only achieved when no modifier was present, but conversion/recovery rates obtained in the replicate experiments carried out with 15 mL supercritical carbon dioxide at 50°C and 200 atm (n = 5), 300 atm (n = 7), and 400 atm (n = 5) were no reproducible (RSD > 50%) and ranged between 10% and 45% (related to the signal obtained for derivatization in vial).
Keywords
cyprodinil; Derivatization; GC/MS; SFE
Tags
PFAS
•
Additional PFAS (formerly XAgency)
•
Expanded PFAS SEM (formerly PFAS 430)
Litsearch: September 2019
PubMed
Not prioritized for screening
Heptafluorobutanoic anhydride
Perfluorobutanoic anhydride
•
^Per- and Polyfluoroalkyl Substances (PFAS)
PFBA (375-22-4)
Literature Search
Pubmed
•
PFBA
Literature Search
Pubmed
Screening Results
Excluded/Not on Topic
Protocol References
Scopus: April 2021
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