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3860069 
Journal Article 
Potential exposure routes and accumulation kinetics for poly- and perfluorinated alkyl compounds for a freshwater amphipod: Gammarus spp. (Crustacea) 
Bertin, D; Labadie, P; Ferrari, BJ; Sapin, A; Garric, J; Geffard, O; Budzinski, H; Babut, M 
2016 
Yes 
Chemosphere
ISSN: 0045-6535
EISSN: 1879-1298 
Elsevier 
155 
Elsevier 
380-387 
English 
Gammarids were exposed to sediments from a deposition site located on the Rhône River (France) downstream of a fluoropolymer manufacturing plant. Gammarids accumulated to various extents four long-chain perfluoroalkyl carboxylic acids (PFCAs) from C9 to C13, one sulfonate, perfluorooctane sulfonate (PFOS) and three of its precursors (the perflurooctane sulfonamide (FOSA), the N-methyl perfluorooctane sulfonamidoacetic acid (MeFOSAA), the N-ethyl perfluorooctane sulfonamidoacetic acid (EtFOSAA) and the 6:2 fluorotelomer sulfonic acid (6:2 FTSA). Whatever the compound, the steady state was not achieved after a 3-week exposure; elimination was almost complete after a 3-week depuration period for perfluorononanoic acid (PFNA), PFOS, the three precursors and the 6:2FTSA. However, this was not the case for long-chain PFCAs, whose elimination rates decreased with increasing chain length. PFAS accumulation in gammarids occurred via the trophic and respiratory pathways, in proportions varying with the carbon chain length and the terminal moiety. 
Perfluorinated compounds; Sediment; Gammarus spp.; Exposure route; Uptake rate; Clearance; BSAF 
PFAS
• FtS 6:2
     Literature Search
          Pubmed
          WOS
• ^Per- and Polyfluoroalkyl Substances (PFAS)
     PFOA (335-67-1) and PFOS (1763-23-1)
          Literature Search – Adverse outcome pathway (2015-present)
               Pubmed
               WOS
     PFNA (375-95-1)
          Literature Search
               Pubmed
               WOS
     PFOSA (754-91-6)
          Literature Search
               WOS
     FtS 6:2 (27619-97-2)
          Literature Search
               Pubmed
               WOS
• PFBA
     Protocol References
• PFNA
     PFNA Literature Search pre-2019
          Pubmed
          WOS
     Literature Search
          Pubmed
          WOS
     Screening Results
          Excluded/Not on Topic
• PFOA (335-67-1) and PFOS (1763-23-1)
     Literature Search – Adverse outcome pathway (2015-present)
          Pubmed
          WOS
     Screening Results
          Excluded/Not on Topic
     Literature Search Update (2013-2019)
          PubMed
          WOS
• PFOSA
     Literature Search
          Pubmed
          WOS
     Screening Results
          Excluded/Not on Topic