SYNTHESIS AND REACTIVITY OF SOME 1,2,4-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES
Baloniak, S; Katrusiak, A
| HERO ID | 4075193 |
|---|---|
| In Press | No |
| Year | 1994 |
| Title | SYNTHESIS AND REACTIVITY OF SOME 1,2,4-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES |
| Authors | Baloniak, S; Katrusiak, A |
| Journal | Polish Journal of Chemistry |
| Volume | 68 |
| Issue | 4 |
| Page Numbers | 683-691 |
| Abstract | The triazolo[4,3-b]pyridazine derivatives were obtained in the reaction of 3-chloro-6-hydrazinopyridazine with acetic acid and ethyl chloroformate. Acting on 6-chloro-3-methyl-1,2,4-triazolo[4,3-b]pyridazine with phosphorus pentachloride, a methyl group in position 3 has unexpectedly been exchanged by chlorine. The mechanism of fusing the triazole ring to the pyridazine system has been studied by the reaction of 3-chloro-6-hydrazinopyridazine with formaldehyde, acetaldehyde, and treatment the resulting Schiff bases by bromine in acetic acid with sodium acetate added. |
| Wosid | WOS:A1994NE92200005 |
| Url | <Go to ISI>://WOS:A1994NE92200005 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Keyword | 1,2,4-TRIAZOLO[4,3-B]PYRIDAZINES; NUCLEOPHILIC SUBSTITUTION; CYCLIZATION MECHANISM |