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HERO ID
4728433
Reference Type
Journal Article
Title
Simultaneous determination of 11 phthalate esters in bottled beverages by graphene oxide coated hollow fiber membrane extraction coupled with supercritical fluid chromatography
Author(s)
Lou, C; Guo, D; Zhang, K; Wu, C; Zhang, P; Zhu, Y
Year
2018
Is Peer Reviewed?
Yes
Journal
Analytica Chimica Acta
ISSN:
0003-2670
EISSN:
1873-4324
Publisher
ELSEVIER SCIENCE BV
Location
AMSTERDAM
Volume
1007
Page Numbers
71-79
Language
English
PMID
29405990
DOI
10.1016/j.aca.2017.12.018
Web of Science Id
WOS:000423843500009
Abstract
Phthalate esters (PAEs) are a group of serious environmental pollutants, which lead to carcinogenicity or tumorigenicity in human body. In this study, a rapid, sensitive and green method by graphene oxide coated hollow fiber membrane extraction (GO-HFME) coupled with supercritical fluid chromatography (SFC) was proposed for the determination of 11 phthalate esters in bottled beverages. Graphene oxide (GO) was prepared and coated onto a porous hollow fiber membrane (HFM) to reinforce the efficiency of membrane extraction. The modified hollow fiber membrane was employed for the extraction of phthalate esters from bottled beverages prior to the determination by the supercritical fluid chromatography with UV detection. To achieve the maximum extraction efficiency, several parameters were investigated including GO concentration, extraction time, desorption solution and desorption time. SFC variables including stationary phase, modifier composition and percentage, column temperature, flow rate and backpressure were studied to improve the separation conditions. Under these optimized conditions, all the studied 11 phthalate esters were well separated and simultaneously determined in 7 min by SFC. The performance of the developed method was evaluated. Good linearity was observed (R ≥ 0.999) in the range of 0.02-10.0 μg/mL with limit of detection (LOD, S/N = 3) ranging from 1.5 to 3.0 ng/mL. Recoveries of all the PAEs for the spiked samples were between 92.1% and 99.3% with satisfactory relative standard deviations (RSD) less than 5.9%. The proposed method is time-saving, green, simple and robust, which will be an alternative way to the analysis of PAEs in real samples.
Tags
IRIS
•
Phthalates – Targeted Search for Epidemiological Studies
Source - August 2018 Update
Pubmed
WOS
Toxline
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