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5024208 
Journal Article 
Monthly Variations in Perfluorinated Compound Concentrations in Groundwater 
Steele, M; Griffith, C; Duran, C 
2018 
Toxics
EISSN: 2305-6304 
MDPI 
BASEL 
n/a 
English 
Large-scale manufacturing of poly- and perfluorinated compounds in the second half of the 20th century has led to their ubiquity in the environment, and their unique structure has made them persistent contaminants. A recent drinking water advisory level issued by the United States Environmental Protection Agency lowered the advisory level concentration of perfluorooctanesulfonic acid (PFOS) and perfluorooctanoic acid (PFOA) from 200 nanograms per liter and 400 nanograms per liter, respectively, to 70 nanograms per liter separately or combined. Small temporal variations in PFOS and PFOA concentrations could be the difference between meeting or exceeding the recommended limit. In this study, newly sampled data from a contaminated military site in Alaska and historical data from former Pease Air Force Base were collected. Data were evaluated to determine if monthly variations within PFOS and PFOA existed. No statistically significant temporal trend was observed in the Alaska data, while the results from Pease, although statistically significant, showed the spread of observed contaminant concentrations around the fitted line is broad (as indicated by the low R² values), indicating that collection date has little value in predicting contaminant concentrations. Though not currently the subject of a US EPA health advisory, data on perfluorobutanesulfonic acid (PFBS), perfluorohexane sulfonic acid (PFHxS), perfluoroheptanoic acid (PFHpA), and perfluorononanoic acid (PFNA) were collected for each site and their average concentrations evaluated. 
PFAS; PFOS; PFOA; perfluorooctane sulfonate; perfluorooctanoic acid 
PFAS
• Additional PFAS (formerly XAgency)
• Expanded PFAS SEM (formerly PFAS 430)
     Litsearch: September 2019
          PubMed
     Not prioritized for screening
     Perfluorooctane
• PFAS 150
     Literature Search Update December 2020
          PubMed
          WOS
     Literature Search August 2019
          PubMed
          Web of Science
     Not prioritized for screening
     Ammonium perfluorooctanoate
     Perfluorinated compounds
     Perfluorobutanesulfonic acid
     Perfluorobutanesulfonyl fluoride
     Perfluoroheptanoic acid
     Perfluorohexanesulfonic acid
     Perfluorononanoic acid
     Perfluorooctane
     Perfluorooctanesulfonic acid
     Perfluorooctanoic acid
• PFBS
     Search
          PubMed
     Lit Search Update: May 2019
          PubMed
     Scopus: April 2021
• PFHpA
     Literature Search Update 2017-2019
          PubMed
• PFHxS
     Database searches
          Pubmed
          Scopus
     Supplemental
          TiAb
          Exposure assessment or characterization (no health outcome)
          Manufacture, engineering, use, treatment, remediation, or laboratory methods
     Literature Search Update April 2023
          Supplemental
               Exposure assessment or characterization (no health outcome)
• PFNA
     Literature Search
          Pubmed
     PFNA May 2019 Update
          Pubmed
     Title and Abstract Screening
          Tagged as Supplemental
               Environmental occurance
               Environmental fate
               Other PFAS
• PFOA (335-67-1) and PFOS (1763-23-1)
     Literature Search Update (2013-2019)
          PubMed