Jump to main content
US EPA
United States Environmental Protection Agency
Search
Search
Main menu
Environmental Topics
Laws & Regulations
About EPA
Health & Environmental Research Online (HERO)
Contact Us
Print
Feedback
Export to File
Search:
This record has multiple attached files:
Add More Files
Attach File(s):
Display Name for File*:
Save
Citation
Tags
HERO ID
5083561
Reference Type
Journal Article
Title
Sensitive determination of perfluoroalkane sulfonamides in water and urine samples by multiple monolithic fiber solid-phase microextraction and liquid chromatography tandem mass spectrometry
Author(s)
Huang, YM; Lu, M; Li, HY; Bai, MD; Huang, XJ
Year
2019
Is Peer Reviewed?
Yes
Journal
Talanta
ISSN:
0039-9140
EISSN:
1873-3573
Volume
192
Page Numbers
24-31
Language
English
PMID
30348384
DOI
10.1016/j.talanta.2018.09.004
Web of Science Id
WOS:000449443900004
Relationship(s)
is supplemented by
11388679
: Supplementary material
Abstract
To extract perfluoroalkane sulfonamides (PFASAs) in water and urine samples effectively, a new adsorbent based on poly (1H,1H,2H,2H-nonafluorohexyl acrylate/vinyboronic anhydride pyridine complex-co-ethylenedimethacrylate) monolith (FBE) was synthesized and used as the extraction phase of multiple monolithic fiber solid-phase microextraction (MMF-SPME). Because there are abundant fluorinated (F-) alkyl chains and boron atoms in the adsorbent, the FBE/MMF-SPME displays satisfactory extraction performance for PFASAs by means of fluorophilic and B-N coordination interactions. Under the most favorable conditions, the FBE/MMF-SPME was combined with HPLC-MS/MS for the sensitive monitoring of ultra-trace PFASAs in environmental water and human urine samples. The limits of detection and limits of quantification achieved for target analytes were in the range of 0.13-1.45 ng/L and 0.44-4.80 ng/L, respectively. The developed FBE/MMF-SPME-HPLC-MS/MS method was successfully applied to quantify the level of PFASAs in water and human urine samples, and ultra-trace target PFASAs were detected in the real samples. The recoveries at different fortified concentrations ranged from 80.3% to 119% with RSD in the range of 0.9-11%. Compared with reported methods, the proposed method exhibits some merits such as high sensitivity, good method precision, low consumption of sample and environmental friendliness.
Keywords
perfluoroalkane sulfonamides; solid-phase microextraction; fluorophilicity; boronate affinity; water; urine
Tags
PFAS
•
Additional PFAS (formerly XAgency)
•
PFOA (335-67-1) and PFOS (1763-23-1)
Literature Search Update (2013-2019)
WOS
Home
Learn about HERO
Using HERO
Search HERO
Projects in HERO
Risk Assessment
Transparency & Integrity